Hybridised production of technetium-99m and technetium-101 with fluorine-18 on a low-energy biomedical cyclotron
Hybridised production of technetium-99m and technetium-101 with fluorine-18 on a low-energy biomedical cyclotron
Johnstone, E. V.; Mayordomo, N.; Mausolf, E. J.
Abstract
New modes of production and supply of short-lived radioisotopes using accelerators
are becoming attractive alternatives to the use of nuclear reactors. In this study, the
use of a compact accelerator neutron source (CANS) was implemented to explore the
production of 99mTc and 101Tc. Irradiations were performed with neutrons generated
from a 16.5 MeV cyclotron utilising the 18O(p, n)18F reaction during routine 18F[FDG]
production in a commercial radiopharmacy. Natural molybdenum targets in metal form
were employed for the production of Tc isotopes of interest via (n, ) reactions on 98Mo
and 100Mo. The production of 99mTc and 101Tc under these conditions is considered
and discussed.
Keywords: Tc-99m; Tc-101; F-18; CANS; Compact accelerator neutron source
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EPJ Techniques and Instrumentation 10(2023)1, 1
DOI: 10.1140/epjti/s40485-023-00089-2
Permalink: https://www.hzdr.de/publications/Publ-35398