Dosimetric system for quantitative cell irradiation experiments with laser-accelerated protons
Dosimetric system for quantitative cell irradiation experiments with laser-accelerated protons
Richter, C.; Karsch, L.; Dammene, Y.; Metzkes, J.; Schramm, U.; Sobiella, M.; Schürer, M.; Weber, A.; Zeil, K.; Pawelke, J.
Abstract
An Integrated DOsimetry and Cell Irradiation System (IDOCIS) with laser-accelerated proton beams was developed, characterized, calibrated and successfully used for systematic in vitro experiments. Due to the broad exponentially shaped energy spectrum, the low energy range of the protons (< 20 MeV) and the high pulse dose, the absolute dosimetry for this beam quality is challenging. Therefore, a dedicated Faraday cup is used as an energy and dose rate independent absolute dosimeter that has been calibrated consistently with three independent methods. A transmission ionization chamber providing online relative dose information is cross-calibrated against the Faraday cup. Providing both online and absolute dose information the IDOCIS allows for quantitative dosimetric and radiobiological studies at current low-energy laser-accelerated proton beams. Finally, first dosimetric characterizations of a laser-accelerated proton beam with the IDOCIS are presented.
Keywords: laser particle acceleration; proton; dosimetry; faraday cup; radiochromic films
Beteiligte Forschungsanlagen
- Strahlungsquelle ELBE DOI: 10.17815/jlsrf-2-58
Verknüpfte Publikationen
- DOI: 10.17815/jlsrf-2-58 is cited by this (Id 15148) publication
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Physics in Medicine and Biology 56(2011)6, 1529-1543
DOI: 10.1088/0031-9155/56/6/002
Cited 46 times in Scopus
Permalink: https://www.hzdr.de/publications/Publ-15148