Publikationen - Institut für Radiopharmazeutische Krebsforschung

1323 Publikationen

2024

Developing blood-brain barrier arterial spin labelling as a non-invasive early biomarker of Alzheimer’s disease (DEBBIE-AD): a prospective observational multicohort study protocol

Padrela, B.; Mahroo, A.; Tee, M.; Sneve, M. H.; Moyaert, P.; et al. (43 authors)

Highlight selection of radiochemistry and radiopharmacy developments by editorial board

Toyohara, J.; Vugts, D.; Kiß, O.; Todde, S.; Li, X.-G.; et al. (24 authors)

Reproducibility of Arterial Spin Labeling Cerebral Blood Flow image processing: A Report of The ISMRM Open Science Initiative for Perfusion Imaging and the ASL MRI Challenge

Paschoal, A. M.; Woods, J. G.; Pinto, J.; Bron, E. E.; Petr, J.; et al. (26 authors)

Value of [18F] FDG PET/CT parameters of the primary tumor in assessing overall survival in NSCLC patients with cN1-cN3 lymph nodes involvement

Cegla, P.; Hofheinz, F.; Czepczyński, R.; Witkowska, K.; van den Hoff, J.; et al. (8 authors)

  • Open Access Logo Reports of Practical Oncology and Radiotherapy 29(2024)1, 97-102
    DOI: 10.5603/rpor.99360

RevCAR-expressing immune effector cells for targeting of Fn14-positive glioblastoma

Abdelfatah Saleh Hassan, H. A.; Mitwasi, N.; Rodrigues Loureiro, L. R.; Kegler, A.; Elizabeth González Soto, K.; et al. (11 authors)

The crystal structure of (2-diphenylphosphanylphenyl) 2-[7-(dimethylamino)-2-oxochromen-4-yl]acetate, C31H26NO4P

Mamat, C.; Köckerling, M.

Improved automated one-pot two-step radiosynthesis of (S)-[18F]FETrp, a radiotracer for PET imaging of indoleamine 2,3-dioxygenase 1 (IDO1)

Maisonial-Besset, A.; Kryza, D.; Kopka, K.; Levesque, S.; Moreau, E.; et al. (7 authors)

Impact of Viscosity on Human Hepatoma Spheroids in Soft Core-Shell Microcapsules

Peng, X.; Janićijević, Ž.; Lemm, S.; Hauser, S.; Knobel, M.; et al. (8 authors)

Bone marrow-derived mesenchymal stromal cells obstruct AML-targeting CD8+ clonal effector and CAR T cell function while promoting a senescence-associated phenotype

Towers, R.; Trombello, L.; Fusenig, M.; Tunger, A.; Baumann, A.-L.; et al. (16 authors)

Alpha-emitting Radionuclides: Current Status and Future Perspectives

Miederer, M.; Benešová-Schäfer, M.; Mamat, C.; Kästner, D.; Pretze, M.; et al. (11 authors)

Design and Development of Transient Sensing Devices for Healthcare Applications

Janićijević, Ž.; Huang, T.; Sandoval Bojorquez, D. I.; Tonmoy, T. H.; Pané, S.; et al. (7 authors)

[¹⁸F]Fluspidine – a PET tracer for imaging of σ1 receptors in the central nervous system

Ludwig, F.-A.; Laurini, E.; Schmidt, J.; Pricl, S.; Deuther-Conrad, W.; et al. (6 authors)

Production of medical radionuclides in the Center for Radiopharmaceutical Tumor Research – a status report

Kreller, M.; Walther, M.; Brühlmann, S. A.; Knieß, T.; Kopka, K.

Portable Droplet-Based Real-Time Monitoring of Pancreatic α-Amylase in Postoperative Patients

Zhao, X.; Kolbinger, F. R.; Distler, M.; Weitz, J.; Makarov, D.; et al. (7 authors)

Production of the PET radionuclide 61Cu via the 62Ni(p,2n)61Cu Nuclear Reaction

Brühlmann, S. A.; Walther, M.; Kopka, K.; Kreller, M.

Preclinical evaluation of an ¹⁸F-labeled Nε-acryloyllysine piperazide for covalent targeting of transglutaminase 2

Wodtke, R.; Laube, M.; Hauser, S.; Meister, S.; Ludwig, F.-A.; et al. (9 authors)

Chelator Impact: Investigating the Pharmacokinetic Behavior of Copper-64 Labeled PD-L1 Radioligands

Krutzek, F.; Donat, C.; Stadlbauer, S.

Position Paper to facilitate patient access to radiopharmaceuticals - considerations for a suitable pharmaceutical regulatory framework

Korde, A.; Patt, M.; Selivanova, S.; Scott, A.; Hesselmann, R.; et al. (15 authors)

The Past, Present, and Future of the Brain Imaging Data Structure (BIDS)

Poldrack, R. A.; Markiewicz, C. J.; Appelhoff, S.; Ashar, Y. K.; Auer, T.; et al. (112 authors)

Longitudinal cerebral perfusion in presymptomatic genetic frontotemporal dementia: GENFI results

Pasternak, M.; Mirza, S.; Luciw, N.; Mutsaerts, H.; Petr, J.; et al. (42 authors)

Improving susceptibility of neuroendocrine tumors to radionuclide therapies: personalized approaches towards complementary treatments

Richter, S.; Steenblock, C.; Lemm, S.; Ziegler, C. G.; Bechmann, N.; et al. (8 authors)

Effect of physical exercise on brain perfusion in chemotherapy-treated breast cancer patients: a randomized controlled trial (PAM study)

Koevoets, E. W.; Petr, J.; Monninkhof, E. M.; Geerlings, M. I.; Witlox, L.; et al. (15 authors)

  • Open Access Logo Journal of Magnetic Resonance Imaging 59(2024)5, 1667-1680
    Online First (2023) DOI: 10.1002/jmri.28967

Brain tumor imaging without gadolinium-based contrast agents: Feasible or Fantasy?

Wamelink, I. J. H. G.; Azizova, A.; Booth, T. C.; Mutsaerts, H. J. M. M.; Ogunleye, A.; et al. (9 authors)

ASL lexicon and reporting recommendations: A consensus report from the ISMRM Open Science Initiative for Perfusion Imaging (OSIPI)

Suzuki, Y.; Clement, P.; Dai, W.; Dolui, S.; Fernández-Seara, M.; et al. (11 authors)

  • Open Access Logo Magnetic Resonance in Medicine 91(2024), 1743-1760
    Online First (2023) DOI: 10.1002/mrm.29815

Shell engineering in soft alginate-based capsules for culturing liver spheroids

Peng, X.; Janićijević, Ž.; Lemm, S.; Laube, M.; Pietzsch, J.; et al. (7 authors)

The Open Science Initiative for Perfusion Imaging (OSIPI): ASL Pipeline inventory

Fan, H.; Mutsaerts, H. J. M. M.; Anazodo, U.; Arteaga, D.; Baas, K. P. A.; et al. (17 authors)

  • Open Access Logo Magnetic Resonance in Medicine 91(2024), 1787-1802
    Online First (2023) DOI: 10.1002/mrm.29869

Preparation of HOPO-containing lariate ethers based on the diaza-18-crown-6 scaffold

Paßler, F.; Belke, L.; Reissig, F.; Kopka, K.; Mamat, C.

2023

Combining Cisplatin with Different Radiation Qualities—Interpretation of Cytotoxic Effects In Vitro by Isobolographic Analysis

Runge, R.; Reissig, F.; Herzog, N.; Oehme, L.; Brogsitter, C.; et al. (6 authors)

Molecular imaging of bacterial outer membrane vesicles based on bacterial surface display

Szöllősi, D.; Hajdrik, P.; Tordai, H.; Horváth, I.; Veres, D. S.; et al. (25 authors)

Selecting active matter according to motility in an acoustofluidic setup: Self-propelled particles and sperm cells

Misko, V. R.; Baraban, L.; Makarov, D.; Huang, T.; Gelin, P.; et al. (10 authors)

Extended-gate field-effect transistor chemo- and biosensors: State of the art and perspectives

Janićijević, Ž.; Nguyen Le, T. A.; Baraban, L.

Preparation of 18F-Labeled Tracers Targeting Fibroblast Activation Protein via Sulfur [18F]Fluoride Exchange Reaction

Craig, A.; Kogler, J.; Laube, M.; Ullrich, M.; Donat, C.; et al. (8 authors)

The revision of the pharmaceutical legislation – it is time to act for nuclear medicine in Europe

Patt, M.; Decristoforo, C.; de Martini, A.; Koole, M.; Oyen, W.; et al. (6 authors)

Targeting colorectal cancer cells using AND-gated Adaptor RevCAR T-cells

González Soto, K. E.; Rodrigues Loureiro, L. R.; Bartsch, T.; Arndt, C.; Kegler, A.; et al. (16 authors)

Methods gold standard in clinic millifluidics multiplexed extended gate field-effect transistor biosensor with gold nanoantennae as signal amplifiers

Janićijević, Ž.; Nguyen Le, T. A.; Alsadig, A.; Cela, I.; Zilenaite, R.; et al. (9 authors)

Immunotheranostic target modules for imaging and navigation of UniCAR T-cells to strike FAP-expressing cells and the tumor microenvironment

Rodrigues Loureiro, L. R.; Hoffmann, L.; Neuber, C.; Rupp, L.; Arndt, C.; et al. (12 authors)

Bacterial filamentation mediates cross-protection against β-lactam antibiotics in droplet microreactors

Zhao, X.; Ruelens, P.; Farr, A. D.; de Visser, J. A. G. M.; Baraban, L.

Combination of tumor asphericity and an extracellular matrix-related prognostic gene signature in non-small cell lung cancer patients

Zschaeck, S.; Klinger, B.; van den Hoff, J.; Cegla, P.; Apostolova, I.; et al. (13 authors)

Exploring the Potential of Nanogels: From Drug Carriers to Radiopharmaceutical Agents

Kubeil, M.; Suzuki, Y.; Casulli, M. A.; Kamal, R.; Hashimoto, T.; et al. (8 authors)

Bispidine Chelators for Radiopharmaceutical Applications with Lanthanide, Actinide and Main Group Metal Ions

Kopp, I.; Cieslik, P.; Anger, K.; Josephy, T.; Neupert, L.; et al. (15 authors)

Exploring Hydrophilic PD-L1 Radiotracers Utilizing Phosphonic Acids: Insights Into Unforeseen Pharmacokinetics

Krutzek, F.; Donat, C.; Stadlbauer, S.

Development of a Highly Specific 18F-labeled Radioligand for Imaging of Sigma-2 Receptor in Brain Tumor

Wang, T.; Wang, J.; Chen, L.; Zhang, X.; Mou, T.; et al. (11 authors)

Asphericity derived from [18F]FDG PET as a new prognostic parameter in cervical cancer patients

Cegla, P.; Hofheinz, F.; Burchardt, E.; Czepczyński, R.; Kubiak, A.; et al. (10 authors)

18F-FDG PET/CT-derived total lesion glycolysis predicts abscess formation in patients with surgically confirmed infective endocarditis: Results of a retrospective study at a tertiary center

Maria Sag, S. J.; Menhart, K.; Hitzenbichler, F.; Schmid, C.; Hofheinz, F.; et al. (10 authors)

Radiomics predictive modeling from dual-time-point FDG PET Ki parametric maps: application to chemotherapy response in lymphoma

Samimi, R.; Shiri, I.; Ahmadyar, Y.; van den Hoff, J.; Kamali-Asl, A.; et al. (9 authors)

Design, Synthesis, and Biological Evaluation of Small Molecule Based Radioligands with Improved Pharmacokinetic Properties for Imaging of Programmed Death Ligand 1

Krutzek, F.; Donat, C.; Ullrich, M.; Stadlbauer, S.

Radiosynthesis and biological evaluation of [¹⁸F]AG-120 for PET imaging of the mutant isocitrate dehydrogenase 1 in gliomas

Lai, T. H.; Wenzel, B.; Dukic-Stefanovic, S.; Teodoro, R.; Arnaud, L.; et al. (14 authors)

Equilibrium Thermodynamics of Macropa Complexes with Selected Metal Isotopes of Radiopharmaceutical Interest

Blei, M. K.; Waurick, L.; Reissig, F.; Kopka, K.; Stumpf, T.; et al. (8 authors)

Lysyl oxidases as targets for cancer therapy and diagnostic imaging

Löser, R.; Kuchar, M.; Wodtke, R.; Neuber, C.; Belter, B.; et al. (8 authors)

MRI-based parameter inference for cerebral perfusion modelling in health and ischaemic stroke

Jósza, T.; Petr, J.; Payne, S. J.; Mutsaerts, H.-J.

A novel ACE2 decoy for both neutralization of SARS-CoV-2 variants and killing of infected cells

Kegler, A.; Drewitz, L.; Arndt, C.; Daglar, C.; Rodrigues Loureiro, L. R.; et al. (27 authors)

Synthesis and In Vitro Biological Evaluation of p-Carborane-based Di-tert-butylphenol Analogs

Braun, S.; Jelača, S.; Laube, M.; George, S.; Hofmann, B.; et al. (11 authors)

FLT3-directed UniCAR T-cell therapy of Acute Myeloid Leukaemia

Peschke, J.; Bergmann, R.; Mehnert, M.; González Soto, K. E.; Rodrigues Loureiro, L. R.; et al. (16 authors)

Design and Biological Evaluation of Small-Molecule PET-Tracers for Imaging of Programmed Death Ligand 1

Krutzek, F.; Donat, C.; Ullrich, M.; Zarschler, K.; Ludik, M.-C.; et al. (9 authors)

Development of the High-Affinity Carborane-Based Cannabinoid Receptor Type 2 PET Ligand [18F]LUZ5-d8

Ueberham, L.; Gündel, D.; Kellert, M.; Deuther-Conrad, W.; Ludwig, F.-A.; et al. (11 authors)

Radiofluorination of an anionic, azide-functionalized teroligomer by copper-catalyzed azide-alkyne cycloaddition

Wenzel, B.; Schmid, M.; Teodoro, R.; Moldovan, R.-P.; Lai, T. H.; et al. (11 authors)

Preclinical Characterization of the 177Lu-Labeled Prostate Stem Cell Antigen (PSCA)-Specific Monoclonal Antibody 7F5

Striese, F.; Neuber, C.; Gräßel, S.; Arndt, C.; Ullrich, M.; et al. (13 authors)

Multivalent adaptor proteins specifically target NK cells carrying a universal chimeric antigen receptor to ErbB2 (HER2)-expressing cancers

Pfeifer Serrahima, J.; Zhang, C.; Oberoi, P.; Bodden, M.; Röder, J.; et al. (13 authors)

Carborane-based Tebufelone Analogs and their Biological Evaluation In Vitro

Braun, S.; Paskas, S.; Laube, M.; George, S.; Hofmann, B.; et al. (11 authors)

Specific and safe targeting of glioblastoma using switchable and logic-gated RevCAR T cells

Abdelfatah Saleh Hassan, H. A.; Mitwasi, N.; Ullrich, M.; Kubeil, M.; Toussaint, M.; et al. (17 authors)

Isonimesulide and its carborane analogues as isoform-selective COX inhibitors and antitumor agents

Useini, L.; Komazec, T.; Laube, M.; Lönnecke, P.; Schädlich, J.; et al. (9 authors)

Comparative saturation binding analysis of ⁶⁴Cu-labeled somatostatin analogs using cell homogenates and intact cells

Ullrich, M.; Brandt, F.; Löser, R.; Pietzsch, J.; Wodtke, R.

Immunotargeting of Cancer Stem Cells.

Köseer, A. S.; Di Gaetano, S.; Arndt, C.; Bachmann, M.; Dubrovska, A.

High-Throughput Gel Microbeads as Incubators for Bacterial Competition Study

Nguyen Le, T. A.; Zhao, X.; Bachmann, M.; Ruelens, P.; de Visser, J. A. G. M.; et al. (6 authors)

Metastatic pheochromocytoma and paraganglioma: somatostatin receptor 2 expression, genetics and therapeutic responses

Fischer, A.; Kloos, S.; Maccio, U.; Friemel, J.; Remde, H.; et al. (33 authors)

Highlight selection of radiochemistry and radiopharmacy developments by editorial board

Kiß, O.; Scott, P.; Behe, M.; Penuelas, I.; Passchier, J.; et al. (21 authors)

Impedimetric Nanobiosensor for the Detection of SARS-CoV-2 Antigens and Antibodies

Sandoval Bojorquez, D. I.; Janićijević, Ž.; Palestina Romero, B.; Oliveros Mata, E. S.; Laube, M.; et al. (14 authors)

Strahlenschutzmaßnahmen bei der Anwendung von PET-Nukliden in der Krebsforschung

Wendler, M.; Kowe, S.

  • Strahlenschutz-Praxis 2(2023), 27-29
    ISSN: 0947-434 X

Genetic, vascular, and amyloid determinants of cerebral blood flow in a preclinical population

Padrela, B. E.; Lorenzini, L.; Collij, L. E.; Vállez García, D.; Coomans, E.; et al. (17 authors)

Imaging blood-brain barrier dysfunction: A state-of-the-art review from a clinical perspective

Moyaert, P.; Padrela, B.; Morgan, C.; Petr, J.; Versijpt, J.; et al. (15 authors)

Advanced MR Techniques for preoperative Glioma Characterization - Part 2

Hangel, G.; Schmitz-Abecassis, B.; Sollmann, N.; Pinto, J.; Arzanforoosh, F.; et al. (41 authors)

Advanced MR Techniques for preoperative Glioma Characterization - Part 1

Hirschler, L.; Sollmann, N.; Schmitz-Abecassis, B.; Pinto, J.; Arzanforoosh, F.; et al. (41 authors)

Nemacol is a Small Molecule Inhibitor of C. elegans Vesicular Acetylcholine Transporter with Anthelmintic Potential

Harrington, S.; Pyche, J.; Andrew, R. B.; Spalholz, T.; Ryan, K. T.; et al. (15 authors)

Synthesis of [18F]FMISO, a hypoxia-specific imaging probe for PET, an overview from a radiochemist’s perspective

Knieß, T.; Zessin, J.; Mäding, P.; Kuchar, M.; Kiß, O.; et al. (6 authors)

Cyclotron-based Production of 67Cu for Radionuclide Theranostics Via the 70Zn(p,α)67Cu Reaction

Brühlmann, S. A.; Walther, M.; Kreller, M.; Reissig, F.; Pietzsch, H.-J.; et al. (7 authors)

Solid-Phase Parallel Synthesis of Dual Histone Deacetylase-Cyclooxygenase Inhibitors

Bachmann, L. M.; Hanl, M.; Feller, F.; Sinatra, L.; Schöler, A.; et al. (8 authors)

Efforts towards PET-activatable red-shifted silicon rhodamines and silicon pyronine dyes

Kramer, C. S.; Kanagasundaram, T.; Matthias, J.; Kopka, K.

A convolutional neural network with self-attention for fully automated metabolic tumor volume delineation of head and neck cancer in [18F]FDG PET/CT

Nikulin, P.; Zschaeck, S.; Maus, J.; Cegla, P.; Lombardo, E.; et al. (20 authors)

Carborane Analogues of Fenoprofen Exhibit Improved Antitumor Activity

Useini, L.; Mojić, M.; Laube, M.; Lönnecke, P.; Mijatović, S. S.; et al. (8 authors)

The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2

Heerwig, A.; Kick, A.; Sommerfeld, P.; Eimermacher, S.; Hartung, F.; et al. (13 authors)

Effect of ISA and chloride on the uptake of niobium(V) by hardened cement paste and C-S-H phases: quantitative description and mechanistic understanding

Jo, Y.; Çevirim-Papaioannou, N.; Franke, K.; Fuss, M.; Pedersen, M.; et al. (9 authors)

In vitro Cytostatic Effect on Tumor Cells by Carborane-based Dual Cyclooxygenase-2 and 5-Lipoxygenase Inhibitors

Braun, S.; Paskas, S.; Laube, M.; George, S.; Hofmann, B.; et al. (11 authors)

Microdialysis reveals anti-inflammatory effects of sulfated glycosaminoglycanes in the early phase of bone healing

Schulze, S.; Neuber, C.; Möller, S.; Pietzsch, J.; Schaser, K.-D.; et al. (6 authors)

Interaction of Catalyst Nanoparticles and Pollutant Molecules in Photocatalytic Wastewater Treatment: Novel Characterization via Dynamic Surface Properties

Javadi, A.; Nourizade, M.; Rahmani, M.; Eckert, K.

Imaging of Gαq proteins in mouse and human organs and tissues

Voss, J. H.; Al-Hroub, H.; Gedschold, R.; Dietrich, J.; Gaffal, E.; et al. (13 authors)

Copper-free click bioconjugation of technetium-99m complexes using strained cyclononyne derivatives

Schlesinger, M.; Jentschel, C.; Pietzsch, H.-J.; Kopka, K.; Mamat, C.

DGN-Handlungsempfehlung (S1-Leitlinie) PSMA-Liganden-PET/CT in der Diagnostik des Prostatakarzinoms Stand: 01/2022 AWMF-Registernummer: 031-055

Afshar-Oromieh, A.; Eiber, M.; Fendler, W.; Schmidt, M.; Rahbar, K.; et al. (18 authors)

Selective a3b4 nicotinic acetylcholine receptor ligand as a potential tracer for drug addiction

Kanasuwan, A.; Deuther-Conrad, W.; Sarasamkan, J.; Chotipanich, C.; Vajragupta, O.; et al. (6 authors)

Current state and Guidance on Arterial Spin Labeling Perfusion MRI in Clinical Neuroimaging

Lindner, T.; Bolar, D. S.; Achten, E.; Barkhof, F.; Bastos-Leite, A. J.; et al. (26 authors)

Improved protocol for the radiosynthesis of [18F]FTC-146: A potent and selective sigma-1 receptor radioligand

Sadeghzadeh, M.; Wenzel, B.; Nikodemus, J.; Florea, A.; Hertel, F.; et al. (9 authors)

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 66(2023)3, 116-125
    DOI: 10.1002/jlcr.4018

Longitudinal and multimodal radiomics models for head-and-neck cancer outcome prediction

Starke, S.; Zwanenburg, A.; Leger, K.; Zöphel, K.; Kotzerke, J.; et al. (9 authors)

A self-assembled dynamic extracellular matrix-like hydrogel system with multi-scale structures for cell bioengineering applications

Xu, Y.; Rothe, R.; Voigt, D.; Sayed, A.; Huang, C.; et al. (13 authors)

Enzymological characterization of ⁶⁴Cu-labeled neprilysin substrates and their application for modulating the renal clearance of targeted radiopharmaceuticals

Brandt, F.; Ullrich, M.; Wodtke, J.; Kopka, K.; Bachmann, M.; et al. (9 authors)

Dipeptide-derived alkynes as potent and selective irreversible inhibitors of cysteine cathepsins

Behring, L.; Ruiz-Gomez, G.; Trapp, C.; Morales, M.; Wodtke, R.; et al. (10 authors)

Epigenetic drugs in somatostatin type 2 receptor radionuclide theranostics and radiation transcriptomics in mouse pheochromocytoma models

Ullrich, M.; Richter, S.; Liers, J.; Drukewitz, S.; Friedemann, M.; et al. (10 authors)

Synthesis, Structure–Activity Relationships, Radiofluorination, and Biological Evaluation of [18F]RM365, a Novel Radioligand for Imaging the Human Cannabinoid Receptor Type 2 (CB2R) in the Brain with PET

Teodoro, R.; Gündel, D.; Deuther-Conrad, W.; Toussaint, M.; Wenzel, B.; et al. (9 authors)

Anti-cancer prodrug cyclophosphamide exerts thrombogenic effects on human venous endothelial cells independent of CYP450 activation – relevance to thrombosis

Krüger-Genge, A.; Köhler, S.; Laube, M.; Haileka, V.; Lemm, S.; et al. (12 authors)

The value of arterial spin labelling perfusion MRI in brain age prediction

Dijsselhof, M.; Barboure, M.; Stritt, M.; Nordhøy, W.; Wink, A. M.; et al. (11 authors)

Calix[4]crowns with perfluoroalkylsulfonylcarboxamide functions: a complexation approach for heavy group 2 metal ions

Reissig, F.; Bauer, D.; Al-Ameed, K.; Luber, S.; Köckerling, M.; et al. (8 authors)

  • Open Access Logo Inorganic Chemistry Frontiers 10(2023), 370-382
    Online First (2022) DOI: 10.1039/d2qi01637k

Palbociclib impairs the proliferative capacity of activated T cells while retaining their cytotoxic efficacy

Arndt, C.; Tunger, A.; Wehner, R.; Rothe, R.; Kourtellari, E.; et al. (16 authors)

Reproducibility of 3T APT-CEST in healthy volunteers and brain glioma patients

Wamelink, I. J. H. G.; Kuijer, J. P. A.; Padrela, B. E.; Zhang, Y.; Barkhof, F.; et al. (9 authors)

  • Open Access Logo Journal of Magnetic Resonance Imaging 57(2023)1, 206-215
    Online First (2022) DOI: 10.1002/jmri.28239

Significance of pulmonary endothelial injury and the role of cyclooxygenase-2 and prostanoid signaling

Nickl, R.; Hauser, S.; Pietzsch, J.; Richter, T.

2022

Clinical Significance of Tumor-Infiltrating Conventional and Plasmacytoid Dendritic Cells in Pancreatic Ductal Adenocarcinoma

Plesca, I.; Benešová, I.; Beer, C.; Sommer, U.; Müller, L.; et al. (15 authors)

Interfacial dynamics of adsorption layers as support of biomedical research and diagnostics

Santini, E.; Nepita, I.; Bykov, A. G.; Ravera, F.; Liggieri, L.; et al. (9 authors)

Pickering foams and parameters influencing their characteristics

Amani, P.; Miller, R.; Javadi, A.; Firouzi, M.

Unfolded Lipase at Interfaces Studied via Interfacial Dilational Rheology: The Impact of Urea

Dowlati, S.; Javadi, A.; Miller, R.; Eckert, K.; Kraume, M.

Synthesis and preclinical evaluation of rhenium and technetium-99m “4 + 1” mixed-ligand complexes bearing quinazoline derivatives as potential EGFR imaging agents

Kiritsis, C.; Shegani, A.; Makrypidi, K.; Roupa, I.; Lazopoulos, A.; et al. (12 authors)

Induction of pulmonary HLA-G expression by SARS-CoV-2 infection

Seliger, B.; Jasinski-Bergner, S.; Masssa, C.; Müller, A.; Biehl, K.; et al. (12 authors)

Towards personalized medicine: one chelator for imaging and therapy with lutetium-177 and actinium-225

Cieslik, P.; Kubeil, M.; Zarschler, K.; Ullrich, M.; Brandt, F.; et al. (12 authors)

Refined Chelator Spacer Moieties Ameliorate the Pharmacokinetics of PSMA-617.

Dos, S. J.; Schäfer, M.; Bauder-Wüst, U.; Beijer, B.; Eder, M.; et al. (14 authors)

Highlight selection of radiochemistry and radiopharmacy developments by editorial board.

Toyohara, J.; Al-Qahtani, M.; Huang, Y.; Cazzola, E.; Todde, S.; et al. (21 authors)

Case report: Incidentally discovered case of pheochromocytoma as a cause of long COVID-19 syndrome

Ziegler, C. G.; Riediger, C.; Gruber, M.; Kunath, C.; Ullrich, M.; et al. (11 authors)

The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents

Keuler, T.; Lemke, C.; Elsinghorst, P. W.; Iriepa, I.; Chioua, M.; et al. (14 authors)

A fluorescence anisotropy assay with guanine nucleotides provides access to functional analysis of Gαi1 proteins

Penanian, A.; Sommerfeld, P.; Kasprzyk, R.; Kühl, T.; Binbay, A.; et al. (14 authors)

Efficient Production of the PET radionuclide 133La for Theranostic Purposes in Targeted Alpha Therapy using the 134Ba(p,2n)133La Reaction

Brühlmann, S. A.; Kreller, M.; Pietzsch, H.-J.; Kopka, K.; Mamat, C.; et al. (7 authors)

Exploring nitric oxide (NO)- releasing celecoxib derivatives as modulators of radioresponse in pheochromocytoma cells

Brandt, F.; Ullrich, M.; Seifert, V.; Haase-Kohn, C.; Richter, S.; et al. (8 authors)

Radiosynthesis and preclinical evaluation of an 18F-labeled tri-azolopyridopyrazine-based inhibitor for neuroimaging of the phosphodiesterase 2A (PDE2A)

Wenzel, B.; Fritzsche, S. R.; Toussaint, M.; Briel, D.; Kopka, K.; et al. (8 authors)

Development of Radiotracers for Imaging of the PD-1/PD-L1 Axis

Krutzek, F.; Kopka, K.; Stadlbauer, S.

Development of a neurotensin-derived 68Ga-labeled PET ligand with high in vivo stability for imaging of NTS1 receptor-expressing tumors

Schindler, L.; Moosbauer, J.; Schmidt, D.; Spruss, T.; Grätz, L.; et al. (13 authors)

Fluorination of silyl prosthetic groups by fluorine mediated silyl ether linker cleavage: a concept study with conditions applicable in radiofluorination

Kramer, C. S.; Greiner, L.; Kopka, K.; Schäfer, M.

Electrokinetic Janus micromotors moving on topographically flat chemical patterns

Huang, T.; Misko, V.; Caspari, A.; Synytska, A.; Ibarlucea, B.; et al. (10 authors)

Cyclam with a phosphinate-bis(phosphonate) pendant arm is a bone-targeting carrier of copper radionuclides

Pazderová, L.; Benešová, M.; Havlíčková, J.; Vojtíčková, M.; Kotek, J.; et al. (15 authors)

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Nanochips assisted peptide screening for clinical development of CAR-T cell immunotherapy

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Long-term excessive dietary phosphate increases arterial blood pressure, activates the renin-angiotensin-aldosterone system, and stimulates sympathetic tone in mice

Latic, N.; Peitzsch, M.; Zupcic, A.; Pietzsch, J.; Erben, R. G.

Impact of sulfated hyaluronan on bone metabolism in diabetic Charcot neuroarthropathy and degenerative arthritis

Schulze, S.; Neuber, C.; Möller, S.; Hempel, U.; Hofbauer, L. C.; et al. (8 authors)

Combining Radiation- with Immunotherapy in Prostate Cancer: Influence of Radiation on T cells

Lindner, D.; Arndt, C.; Loureiro, L. R.; Feldmann, A.; Kegler, A.; et al. (11 authors)

Modulating the pharmacokinetic profile of Actinium-225-labeled macropa-derived radioconjugates by dual targeting of PSMA and albumin

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The Open-Access European Prevention of Alzheimer’s Dementia (EPAD) MRI dataset and processing workflow

Lorenzini, L.; Ingala, S.; Wink, A. M.; Kuijer, J. P. A.; Wottschel, V.; et al. (30 authors)

1-(4-Fluorobenzoyl)-9H-carbazole

Laube, M.; König, J.; Köckerling, M.; Knieß, T.

PET Imaging of Cholinergic Neurotransmission in Neurodegenerative Disorders

Tiepolt, S.; Meyer, P. M.; Patt, M.; Deuther-Conrad, W.; Hesse, S.; et al. (7 authors)

Recent technical developments in ASL: A Review of the State of the Art

Hernandez-Garcia, L.; Aramendia, V.; Dai, W.; Bolar, D.; Fernández-Seara, M. A.; et al. (21 authors)

Correlation Between Quantitative PSMA PET Parameters and Clinical Risk Factors in Non-Metastatic Primary Prostate Cancer Patients

Zschaeck, S.; Andela, S. B.; Amthauer, H.; Furth, C.; Rogasch, J. M.; et al. (8 authors)

Switching on Cytotoxicity of Water-Soluble Diiron Organometallics by UV Irradiation

Biancalana, L.; Kubeil, M.; Schoch, S.; Zacchini, S.; Marchetti, F.

Real-Time Monitoring of Blood Parameters in the Intensive Care Unit: State-of-the-Art and Perspectives

Bockholt, R.; Paschke, S.; Heubner, L.; Ibarlucea, B.; Laupp, A.; et al. (13 authors)

Novel radioiodinated and radiofluorinated analogues of FT-2102 for SPECT or PET imaging of mIDH1 mutant tumours

Weber, V.; Arnaud, L.; Dukic-Stefanovic, S.; Wenzel, B.; Roux, V.; et al. (12 authors)

A Beginner’s Guide to Arterial Spin Labeling (ASL) Image Processing

Clement, P.; Petr, J.; Dijsselhof, M. B.; Padrela, B.; Pasternak, M.; et al. (14 authors)

Investigation of Tumor Cells and Receptor-Ligand Simulation Models for the Development of PET Imaging Probes Targeting PSMA and GRPR and a Possible Crosstalk between the Two Receptors

Liolios, C.; Patsis, C.; Lambrinidis, G.; Tzortzini, E.; Roscher, M.; et al. (8 authors)

Investigation of radiotracer metabolic stability in vitro with CYP-overexpressing hepatoma cell lines

Lemm, S.; Köhler, S.; Wodtke, R.; Jung, F.; Küpper, J.-H.; et al. (7 authors)

Local control after locally ablative, image-guided radiotherapy of oligometastases identified by Gallium-68-PSMA-Positron Emission Tomography in castration-sensitive prostate cancer patients (OLI-P)

Hölscher, T.; Baumann, M.; Kotzerke, J.; Zöphel, K.; Paulsen, F.; et al. (13 authors)

Targeting CD10 on B-Cell Leukemia Using the Universal CAR T-Cell Platform (UniCAR)

Mitwasi, N.; Arndt, C.; Loureiro, L. R.; Kegler, A.; Fasslrinner, F.; et al. (11 authors)

Radiopharmazie des vergangenen Jahrzehnts

Steinbach, J.; Kopka, K.

Atherosclerotic risk is associated with cerebral perfusion – a cross-sectional study using arterial spin labelling MRI

Hafdi, M.; Mutsaerts, H. J.; Petr, J.; Richard, E.; van Dalen, J. W.

Introducing micro physiological systems to evaluate new radiopharmaceuticals: First attempts with radiolabeled cetuximab

Sihver, W.; Nitt-Weber, A.-K.; Behrens, S.; Ullrich, M.; Pietzsch, H.-J.; et al. (8 authors)

Development and functional characterization of a versatile radio-/immunotheranostic tool for prostate cancer management

Arndt, C.; Bergmann, R.; Striese, F.; Merkel, K.; Máthé, D.; et al. (21 authors)

Validation of CD98hc as a therapeutic target for a combination of radiation and immunotherapies in head and neck squamous cell carcinoma

Köseer, A. S.; Loureiro, L. R.; Jureczek, J.; Mitwasi, N.; González Soto, K. E.; et al. (14 authors)

Personalized drug testing in human pheochromocytoma/paraganglioma primary cultures

Wang, K.; Schütze, I.; Gulde, S.; Bechmann, N.; Richter, S.; et al. (38 authors)

Application of a fluorescence anisotropy-based assay to quantify transglutaminase 2 activity in cell lysates

Hauser, S.; Sommerfeld, P.; Wodtke, J.; Hauser, C.; Schlitterlau, P.; et al. (9 authors)

Synthesis and characterization of the two enantiomers of a chiral sigma-1 receptor radioligand: (S)-(+)- and (R)-(-)-[18F]FBFP

Wang, T.; Zhang, Y.; Zhang, X.; Chen, L.; Zheng, M.-Q.; et al. (10 authors)

Carboranyl analogues of mefenamic acid and their biological evaluation

Useini, L.; Mojic, M.; Laube, M.; Lönnecke, P.; Dahme, J.; et al. (10 authors)

Dual-Labelling Strategies for Nuclear and Fluorescence Molecular Imaging: Current Status and Future Perspectives

Kubeil, M.; Santana Martinez, I. I.; Bachmann, M.; Kopka, K.; Tuck L., K.; et al. (6 authors)

A New Class of PSMA-617-Based Hybrid Molecules for Preoperative Imaging and Intraoperative Fluorescence Navigation of Prostate Cancer

Eder, A.; Matthias, J.; Schäfer, M.; Schmidt, J.; Steinacker, N.; et al. (11 authors)

Comparison of Image Quality and Spatial Resolution Between 18F, 68Ga and 64Cu Phantom Measurements Using a Digital Biograph Vision PET/CT

Braune, A.; Oehme, L.; Freudenberg, R.; Hofheinz, F.; van den Hoff, J.; et al. (7 authors)

Influences on PET Quantification and Interpretation

Rogasch, J.; Hofheinz, F.; van Heek, L.; Voltin, C.; Boellaard, R.; et al. (6 authors)

Enhanced survival of high-risk medulloblastoma-bearing mice after multimodal treatment with radiotherapy, decitabine, and abacavir

Gringmuth, M.; Walther, J.; Greiser, S.; Toussaint, M.; Schwalm, B.; et al. (9 authors)

Multisite Dopamine Sensing with Femtomolar Resolution Using a CMOS Enabled Aptasensor Chip

Baraban, L.; Seichepine, F.; Sessi, V.; Ibarlucea, B.; Klinghammer, S.; et al. (13 authors)

Strained Ammonium Precursors for Radiofluorinations

Reissig, F.; Mamat, C.

Beyond Active Colloids: From Functional Materials to Microscale Robotics

Simmchen, J.; Baraban, L.; Wang, W.

Amphiphilic Anionic Oligomer-Stabilized Calcium Phosphate Nanoparticles with Prospects in siRNA Delivery via Convection-Enhanced Delivery

Mitrach, F.; Schmid, M.; Toussaint, M.; Dukic-Stefanovic, S.; Deuther-Conrad, W.; et al. (12 authors)

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Bernardes, E.; Caravan, P.; van Dam, M.; Deuther-Conrad, W.; Ellis, B.; et al. (23 authors)

A pharmacokinetic and metabolism study of the TRPC6 inhibitor SH045 in mice by LC-MS/MS

Chai, X.-N.; Ludwig, F.-A.; Müglitz, A.; Gong, Y.; Schaefer, M.; et al. (7 authors)

Characterization of protein corona formation on nanoparticles via the analysis of dynamic interfacial properties: Bovine serum albumin - silica particle interaction

Shourni, S.; Javadi, A.; Hosseinpour, N.; Bahramian, A.; Raoufi, M.

Experimental techniques to study protein–surfactant interactions: New insights into competitive adsorptions via drop subphase and Interface exchange

Javadi, A.; Dowlati, S.; Shourni, S.; Miller, R.; Kraume, M.; et al. (7 authors)

Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [¹⁸F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain

Clauß, O.; Schäker-Hübner, L.; Wenzel, B.; Toussaint, M.; Deuther-Conrad, W.; et al. (13 authors)

11C-Methionine Uptake in the Lactating Human Breast

Michler, E.; Hilliger, S.; Kopka, K.; Kotzerke, J.

EANM Position on the In-House Preparation of Radiopharmaceuticals

Hendrikse, H.; Kiß, O.; Kunikowska, J.; Wadsak, W.; Decristoforo, C.; et al. (6 authors)

Structure-Based Design, Optimization and Development of [18F]LU13, a novel radioligand for CB2R Imaging in the Brain with PET

Gündel, D.; Deuther-Conrad, W.; Ueberham, L.; Kaur, S.; Otikova, E.; et al. (14 authors)

A self-assembled matrix system for cell-bioengineering applications in different dimensions, scales, and geometries

Xu, Y.; Patino Gaillez, M.; Zheng, K.; Voigt, D.; Cui, M.; et al. (16 authors)

ASL-BIDS, the brain imaging data structure extension for arterial spin labeling

Clement, P.; Castellaro, M.; Okell, T. W.; Thomas, D. L.; Vandemaele, P.; et al. (21 authors)

Arterial Spin-Labeling Parameters and Their Associations with Risk Factors, Cerebral Small-Vessel Disease, and Etiologic Subtypes of Cognitive Impairment and Dementia

Gyanwali, B.; Seng Tan, C.; Petr, J.; Tirado Escobosa, L. L.; Vrooman, H.; et al. (8 authors)

Association of arterial spin labeling parameters with cognitive decline, vascular events and mortality in a memory-clinic sample

Gyanwali, B.; Mutsaerts, H. J. M. M.; Seng Tan, C.; Rajab Kaweilh, O.; Petr, J.; et al. (7 authors)

Cerebral perfusion and the risk for cognitive decline and dementia in community dwelling older people

Abdulrahman, H.; Hafdi, M.; Mutsaerts, H. J. M. M.; Nederveen, A. J.; Petr, J.; et al. (8 authors)

A convenient route to new (radio)fluorinated and (radio)iodinated cyclic tyrosine analogues.

Noelia Chao, M.; Chezal, J.-M.; Debiton, E.; Canitrot, D.; Witkowski, T.; et al. (12 authors)

The role of transglutaminase 2 in the radioresistance of melanoma cells

Aepler, J.; Wodtke, J.; Wodtke, R.; Haase-Kohn, C.; Löser, R.; et al. (7 authors)

Therapeutic Potential of Nitric Oxide releasing Selective Estrogen Receptor Modulators (NO-SERMs) in Malignant Melanoma

Bechmann, N.; Calsina, B.; Richter, S.; Pietzsch, J.

Bis(amido)bis(oxinate)diamine ligands for theranostic radiometals

Southcott, L.; Whetter, J. N.; Wharton, L.; Patrick, B. O.; Zarschler, K.; et al. (9 authors)

EANM Guideline on Quality Risk Management for radiopharmaceuticals

Gillings, N.; Hjelstuen, O.; Behe, M.; Decristoforo, C.; Elsinga, P.; et al. (15 authors)

Cyclotrons operated for Nuclear Medicine and Radiopharmacy in the German speaking D-A-CH countries: An update on current status and trends

Zippel, C.; Ermert, J.; Patt, M.; Gildehaus, F. J.; Ross, T. L.; et al. (12 authors)

Automated radiosynthesis of the adenosine A2A receptor-targeting radiotracer [18F]FLUDA

Lai, T. H.; Wenzel, B.; Moldovan, R.-P.; Brust, P.; Kopka, K.; et al. (6 authors)

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 65(2022), 162-166
    DOI: 10.1002/jlcr.3970

Quantitation of the A2A adenosine receptor density in the striatum of mice and pigs with [18F]FLUDA by positron emission tomography

Gündel, D.; Toussaint, M.; Lai, T. H.; Deuther-Conrad, W.; Cumming, P.; et al. (10 authors)

Non-invasive assessment of locally overexpressed human adenosine 2A receptors in the heart of transgenic mice

Gündel, D.; Lai, T. H.; Dukic-Stefanovic, S.; Teodoro, R.; Deuther-Conrad, W.; et al. (13 authors)

“Clickable” albumin binders for modulating the tumor uptake of targeted radiopharmaceuticals

Brandt, F.; Ullrich, M.; Laube, M.; Kopka, K.; Bachmann, M.; et al. (10 authors)

Towards Optimized Bioavailability of 99mTc‑Labeled Barbiturates for Non‑invasive Imaging of Matrix Metalloproteinase Activity

Honold, L.; Austrup, M.; Faust, A.; Konken, C.; Schwegmann, K.; et al. (11 authors)

A systematic review on the use of quantitative imaging to detect cancer therapy adverse effects in normal-appearing brain tissue

Petr, J.; Hogeboom, L.; Nikulin, P.; Wiegers, E.; Schroyen, G.; et al. (20 authors)

  • Open Access Logo Magnetic Resonance Materials in Physics, Biology and Medicine 35(2022), 163-186
    Online First (2021) DOI: 10.1007/s10334-021-00985-2

Tumor irradiation in mice with a laser-accelerated proton beam

Kroll, F.; Brack, F.-E.; Bernert, C.; Bock, S.; Bodenstein, E.; et al. (31 authors)

Role of TRPC6 in Kidney Damage after Acute Ischemic Kidney Injury

Zheng, Z.; Tsvetkov, D.; Bartolomaeus, T.; Erdogan, C.; Krügel, U.; et al. (15 authors)

Discovery and development of brain-penetrant 18F-labeled radioligands for neuroimaging of the sigma-2 receptors

Zhang, Y.; Wang, T.; Zhang, X.; Deuther-Conrad, W.; Fu, H.; et al. (10 authors)

Cisplatin - A more Efficient Drug in Combination with Radionuclides?

Reissig, F.; Runge, R.; Naumann, A.; Kotzerke, J.

Overestimation of grey matter atrophy in glioblastoma patients following radio(chemo)therapy

Gommlich, A.; Raschke, F.; Petr, J.; Seidlitz, A.; Jentsch, C.; et al. (12 authors)

  • Open Access Logo Magnetic Resonance Materials in Physics, Biology and Medicine 35(2022), 145-152
    Online First (2021) DOI: 10.1007/s10334-021-00922-3

Preparation of calix[4]arenes for chelation of selected divalent cations

Blumberg, M.; Al-Ameed, K.; Eiselt, E.; Luber, S.; Mamat, C.

Cerebral blood flow of the frontal lobe in untreated children with trigonocephaly vs healthy controls: an arterial spin labeling study

de Planque, C. A.; Petr, J.; Gaillard, L.; Mutsaerts, H. J.; van Veelen, M. L. C.; et al. (8 authors)

CRISPR/Cas9 mediated knockout of cyclooxygenase-2 gene inhibits invasiveness in A2058 melanoma cells

Haase-Kohn, C.; Laube, M.; Donat, C.; Belter, B.; Pietzsch, J.

2021

Enzymatic Hydrolysis of Triglycerides at the Water–Oil Interface Studied via Interfacial Rheology Analysis of Lipase Adsorption Layers

Javadi, A.; Dowlati, S.; Shourni, S.; Rusli, S.; Eckert, K.; et al. (7 authors)

CTAB-Silica nanoparticle complexes - dynamic surface tension measurements and modeling

Javadi, A.; Jafarlou, A.; Eckert, K.; Miller, R.

Prognostic Value of Pretherapeutic Primary Tumour MTV from [18F]FDG PET in Radically Treated Cervical Cancer Patients

Cegla, P.; Hofheinz, F.; CholewińSki, W.; Czepczynski, R.; Kubiak, A.; et al. (9 authors)

Rapid Detection of SARS-CoV-2 Antigens and Antibodies Using OFET Biosensors Based on a Soft and Stretchable Semiconducting Polymer

Ditte, K.; Nguyen Le, T. A.; Ditzer, O.; Isabel Sandoval Bojorquez, D.; Chae, S.; et al. (8 authors)

Molecular Response to Combined Molecular- and External Radiotherapy in Head and Neck Squamous Cell Carcinoma (HNSCC).

Rassamegevanon, T.; Feindt, L.; Koi, L.; Müller, J.; Freudenberg, R.; et al. (16 authors)

Rational Linker Design to Accelerate Excretion and Reduce Background Uptake of Peptidomimetic PSMA-Targeting Hybrid Molecules.

Eder, A.; Schäfer, M.; Schmidt, J.; Bauder-Wüst, U.; Roscher, M.; et al. (9 authors)

Leptin counteracts hypothermia in hypothyroidism through its pyrexic effects and by stabilizing serum thyroid hormone levels

Weiner, J.; Roth, L.; Kranz, M.; Brust, P.; Boelen, A.; et al. (13 authors)

Radiolabeled Silicon-Rhodamines as Bimodal PET/SPECT-NIR Imaging Agents

Kanagasundaram, T.; Laube, M.; Wodtke, J.; Kramer, S. C.; Stadlbauer, S.; et al. (7 authors)

A Small Step, a Giant Leap: Somatic Hypermutation of a Single Amino Acid Leads to Anti-La Autoreactivity

Bartsch, T.; Arndt, C.; Loureiro, L. R.; Kegler, A.; Puentes-Cala, E.; et al. (10 authors)

Chelators for treatment of iron and copper overload: Shift from low-molecular-weight compounds to polymers

Hruby, M.; Santana Martinez, I. I.; Stephan, H.; Pouckova, P.; Benes, J.; et al. (6 authors)

Intraindividual comparison of [68Ga]-Ga-PSMA-11 and [18F]-F-PSMA-1007 in prostate cancer patients: a retrospective single-center analysis.

Hoberück, S.; Löck, S.; Borkowetz, A.; Sommer, U.; Winzer, R.; et al. (12 authors)

Solid-phase synthesis of selectively mono-fluorobenz(o)ylated polyamines as a basis for for the Development of 18F-Labeled Radiotracers

Wodtke, R.; Pietzsch, J.; Löser, R.

Targeting acute myeloid leukemia using the RevCAR platform: a programmable, switchable and combinatorial strategy

Kittel-Boselli, E.; González Soto, K. E.; Loureiro, L. R.; Hoffmann, A.; Bergmann, R.; et al. (16 authors)

[nat/89Zr][Zr(pypa)]: Thermodynamically Stable and Kinetically Inert Binary Nonadentate Complex for Radiopharmaceutical Applications

Southcott, L.; Li, L.; Brian, P.; Stephan, H.; de Guadalupe Jaraquemeda-Pelaez, M.; et al. (6 authors)

Strategic Evaluation of the Traceless Staudinger Ligation for Radiolabeling with the Tricarbonyl Core

Mamat, C.; Jentschel, C.; Köckerling, M.; Steinbach, J.

Highlight selection of radiochemistry and radiopharmacy developments by editorial board

Alves, F.; Antunes, I.; Cazzola, E.; Cleeren, F.; Cornelissen, B.; et al. (21 authors)

And yet it moves: Oxidation of the Nuclear Autoantigen La/SS-B is the Driving Force for Nucleo-Cytoplasmic Shuttling

Berndt, N.; Bippes, C. C.; Michalk, I.; Bartsch, T.; Arndt, C.; et al. (20 authors)

Radiolabeled PSMA inhibitors

Neels, O.; Kopka, K.; Liolios, C.; Afshar-Oromieh, A.

Pharmacokinetic studies of [⁶⁸Ga]Ga‑PSMA‑11 in patients with biochemical recurrence of prostate cancer: detection, differences in temporal distribution and kinetic modelling by tissue type

Strauss, D. S.; Sachpekidis, C.; Kopka, K.; Pan, L.; Haberkorn, U.; et al. (6 authors)

Final Results of the Prospective Biomarker Trial PETra: [11C]-MET-Accumulation in Postoperative PET/MRI Predicts Outcome after Radiochemotherapy in Glioblastoma

Seidlitz, A.; Beuthien-Baumann, B.; Löck, S.; Jentsch, C.; Platzek, I.; et al. (16 authors)

An In Situ Activity Assay for Lysyl Oxidases

Wang, H.; Poe, A.; Pak, L.; Jandu, S.; Nandakumar, K.; et al. (8 authors)

Aktuelle Entwicklungen aus den Radiopharmazeutischen Wissenschaften für theranostische Anwendungen - Editorial

Mamat, C.; Kopka, K.

Epileptogenic zone detection in MRI negative epilepsy using adaptive thresholding of arterial spin labeling data

Gajdoš, M.; Říha, P.; Kojan, M.; Doležalová, I.; Mutsaerts, H. J. M. M.; et al. (7 authors)

H2pyhox - Octadentate Bis(pyridyloxine)

Southcott, L.; Wang, X.; Choudhary, N.; Wharton, L.; Patrick, B.; et al. (11 authors)

Coexistence of fluorescent Escherichia coli strains in millifluidic droplet reactors

Zhao, X.; Illing, R.; Ruelens, P.; Bachmann, M.; Cuniberti, G.; et al. (7 authors)

Pathophysiological Changes in the Enteric Nervous System of Rotenone-Exposed Mice as Early Radiological Markers for Parkinson's Disease

Schaffernicht, G.; Shang, Q.; Stievenard, A.; Bötzel, K.; Dening, Y.; et al. (16 authors)

Modulation of γ-secretase activity by a carborane-based flurbiprofen analogue

Saretz, S.; Basset, G.; Useini, L.; Laube, M.; Pietzsch, J.; et al. (10 authors)

Development of [18F]LU14 for PET Imaging of Cannabinoid Receptor Type 2 in the Brain

Teodoro, R.; Gündel, D.; Ueberham, L.; Toussaint, M.; Bormans, G.; et al. (8 authors)

Development of fluorinated and methoxylated benzothiazole derivatives as highly potent and selective cannabinoid CB2 receptor ligands

Aly, M. W.; Ludwig, F.-A.; Deuther-Conrad, W.; Brust, P.; Abadi, A. H.; et al. (7 authors)

Synthesis of novel fluorinated xanthine derivatives with high adenosine A2B receptor binding affinity

Lindemann, M.; Dukic-Stefanovic, S.; Hinz, S.; Deuther-Conrad, W.; Teodoro, R.; et al. (10 authors)

Design, radiosynthesis and preliminary biological evaluation in mice of a brain-penetrant 18F-labelled σ2 receptor ligand

Moldovan, R.-P.; Gündel, D.; Teodoro, R.; Ludwig, F.-A.; Fischer, S.; et al. (10 authors)

Aktuelle radiopharmazeutische Entwicklungen für die theranostische Anwendung

Neels, O.; Kratochwil, C.; Patt, M.

Predicting the Risk of Metastases by PSMA-PET/CT—Evaluation of 335 Men with Treatment-Naïve Prostate Carcinoma.

Koerber, S.; Boesch, J.; Kratochwil, C.; Schlampp, I.; Ristau, J.; et al. (16 authors)

Conductive hydrogels with dynamic reversible networks for biomedical applications

Xu, Y.; Patino Gaillez, M.; Rothe, R.; Hauser, S.; Voigt, D.; et al. (7 authors)

Two Be or Not Two Be: The Nuclear Autoantigen La/SS-B Is able to form Dimers and Oligomers in a Redox Dependent Manner

Berndt, N.; Bippes, C. C.; Michalk, I.; Bachmann, D.; Bachmann, J.; et al. (21 authors)

Dissolution-based uptake of CeO2 nanoparticles by fresh water shrimp – A dual-radiolabelling study of the fate of anthropogenic cerium in water organisms

Schymura, S.; Rybkin, I.; Uygan, S. S. S.; Drev, S.; Podlipec, R.; et al. (10 authors)

Impact of surface charge on the motion of light-activated Janus micromotors

Huang, T.; Ibarlucea, B.; Caspari, A.; Synytska, A.; Cuniberti, G.; et al. (7 authors)

Development and Validation of a GMP-Compliant High-Pressure Liquid Chromatography Method for the Determination of the Chemical and Radiochemical Purity of [18F]PSMA-1007, a PET Tracer for the Imaging of Prostate Cancer

Katzschmann, I.; Marx, H.; Kopka, K.; Hennrich, U.

Synthesis and application of a thiol-reactive HBED-type chelator for development of easy-toproduce Ga-radiopharmaceutical kits and imaging probes

Klika, K.; Da, P. C.; Kopka, K.; Smith, G.; Makarem, A.

Development of an 18F-labelled irreversible inhibitor of transglutaminase 2 as radiometric tool for quantitative expression profiling in cells and tissues

Wodtke, R.; Wodtke, J.; Hauser, S.; Laube, M.; Bauer, D.; et al. (11 authors)

Highlight selection of radiochemistry and radiopharmacy developments by editorial board

Aime, S.; Al-Qahtani, M.; Behe, M.; Bormans, G.; Carlucci, G.; et al. (23 authors)

Towards Targeted Alpha Therapy with Actinium 225: Chelators for Mild Condition Radiolabeling and Targeting PSMA – a Proof of Concept Study

Reissig, F.; Bauer, D.; Zarschler, K.; Novy, Z.; Bendova, K.; et al. (9 authors)

Using perfusion contrast for spatial normalization of ASL MRI images in a pediatric craniosynostosis population

de Planque, C. A.; Mutsaerts, H. J. M. M.; Keil, V. C. W.; Erler, N. S.; Dremmen, M. H. G.; et al. (7 authors)

Cytoplasmic localization of prostate-specific membrane antigen inhibitors may confer advantages for targeted cancer therapies.

Matthias, J.; Engelhardt, J.; Schäfer, M.; Bauder-Wüst, U.; Meyer, P.; et al. (10 authors)

Emerging radionuclides in a regulatory framework for medicinal products – how do they fit?

Decristoforo, C.; Neels, O.; Patt, M.

Challenges on cyclic nucleotide phosphodiesterases imaging with positron emission tomography: Novel radioligands and (pre-)clinical insights since 2016

Schröder, S.; Scheunemann, M.; Wenzel, B.; Brust, P.

Convergent Synthesis of Diversified Reversible Network Leads to Liquid Metal-Containing Conductive Hydrogel Adhesives

Xu, Y.; Rothe, R.; Voigt, D.; Hauser, S.; Cui, M.; et al. (11 authors)

Radiotherapy enhances uptake and efficacy of 90Y-cetuximab: A preclinical trial

Dietrich, A.; Andreeff, M.; Koi, L.; Bergmann, R.; Schubert, M.; et al. (15 authors)

The Impact of Barium Isotopes in Radiopharmacy and Nuclear Medicine – from Past to Presence

Reissig, F.; Kopka, K.; Mamat, C.

Highlight selection of radiochemistry and radiopharmacy developments by editorial board (January-June 2020).

Al-Qahtani, M.; Behe, M.; Bormans, G.; Carlucci, G.; Dasilva, J.; et al. (19 authors)

Die Bedeutung des Elementes Barium in der Nuklearmedizin

Reissig, F.; Kopka, K.; Mamat, C.

Validation of an LC-MS/MS method to quantify the new TRPC6 inhibitor SH045 (larixyl N-methylcarbamate) and its application in an exploratory pharmacokinetic study in mice

Chai, X.-N.; Ludwig, F.-A.; Müglitz, A.; Schaefer, M.; Yin, H.-Y.; et al. (8 authors)

Development of a ghrelin receptor inverse agonist for positron emission tomography

Bergmann, R.; Chollet, C.; Els-Heindl, S.; Ullrich, M.; Berndt, N.; et al. (9 authors)

From research to clinical practice: a European neuroradiological survey on quantitative advanced MRI implementation

Manfrini, E.; Smits, M.; Thust, S.; Geiger, S.; Bendella, Z.; et al. (8 authors)

The PSMA-11-derived hybrid molecule PSMA-914 specifically identifies prostate cancer by preoperative PET/CT and intraoperative fluorescence imaging

Eder, A.; Omrane, M.; Stadlbauer, S.; Roscher, M.; Khoder, W.; et al. (11 authors)

Men who stare at bone: multimodal monitoring of bone healing

Schulze, S.; Rothe, R.; Neuber, C.; Hauser, S.; Ullrich, M.; et al. (7 authors)

T Cell Mediated Conversion of a Non-anti-La Reactive B cell to an Autoreactive anti-La B Cell by Somatic Hypermutation

Bachmann, M.; Bartsch, T.; Bippes, C. C.; Bachmann, D.; Puentes-Cala, E.; et al. (20 authors)

Preclinical evaluation of [18F]FACH in healthy mice and piglets: An 18F-labeled ligand for imaging of monocarboxylate transporters with PET

Gündel, D.; Sadeghzadeh, M.; Deuther-Conrad, W.; Wenzel, B.; Cumming, P.; et al. (13 authors)

  • Open Access Logo International Journal of Molecular Sciences 22(2021)4, 1645
    DOI: 10.3390/ijms22041645
    ISSN: 1422-0067

Metal ion size profoundly affects H3glyox chelate chemistry

Choudhary, N.; Barett, K.; Kubeil, M.; Radchenko, V.; Engle, J.; et al. (8 authors)

Synthesis and biological evaluation of a novel 18F-labeled radiotracer for PET imaging of the adenosine A2A receptor

Lai, T. H.; Toussaint, M.; Teodoro, R.; Dukic-Stefanovic, S.; Kranz, M.; et al. (8 authors)

Development of 18F-labeled radiotracers for PET imaging of the adenosine A2A receptor: Synthesis, radiolabeling and preliminary biological evaluation

Lai, T. H.; Schröder, S.; Toussaint, M.; Dukic-Stefanovic, S.; Kranz, M.; et al. (11 authors)

Improved in vivo PET imaging of the adenosine A2A receptor in the brain using [18F]FLUDA, a deuterated radiotracer with high metabolic stability

Lai, T. H.; Toussaint, M.; Teodoro, R.; Dukic-Stefanovic, S.; Gündel, D.; et al. (14 authors)

In vitro and in vivo evaluation of fluorinated indanone derivatives as potential positron emission tomography agents for the imaging of monoamine oxidase B in the brain

Dukic-Stefanovic, S.; Lai, T. H.; Toussaint, M.; Clauß, O.; Jevtić, I. I.; et al. (13 authors)

HIF2alpha-associated pseudohypoxia promotes radioresistance in pheochromocytoma: insights from 3D models

Seifert, V.; Richter, S.; Bechmann, N.; Bachmann, M.; Ziegler, C. G.; et al. (7 authors)

High denticity oxinate-linearbackbone chelating ligand for diagnostic radiometal ions [111In]In3+ and [89Zr]Zr4+

Southcott, L.; Wang, X.; Wharton, L.; Yang, H.; Radchenko, V.; et al. (9 authors)

Development of the First Potential Nonpeptidic Positron Emission Tomography Tracer for the Imaging of CCR2 Receptors

Wagner, S.; De, M. G. F.; Silva, D.; Ortiz, Z. N.; Zweemer, A.; et al. (14 authors)

Screening Arrays of Laminin Peptides on Modified Cellulose for Promotion of Adhesion of Primary Endothelial and Neural Precursor Cells

Wetzel, R.; Hauser, S.; Lin, W.; Berg, P.; Werner, C.; et al. (8 authors)

On the consensus nomenclature rules for radiopharmaceutical chemistry – reconsideration of radiochemical conversion

Herth, M.; Ametamey, S.; Antuganov, D.; Bauman, A.; Berndt, M.; et al. (26 authors)

Response of endothelial cells to gelatin-based hydrogels

Krüger-Genge, A.; Hauser, S.; Neffe, A. T.; Liu, Y.; Lendlein, A.; et al. (7 authors)

Immunocompatibility and non-thrombogenicity of gelatin-based hydrogels

Krüger-Genge, A.; Tondera, C.; Hauser, S.; Braune, S.; Görs, J.; et al. (11 authors)

  • Open Access Logo Clinical Hemorheology and Microcirculation 77(2021), 335-350
    DOI: 10.3233/CH-201028

Radiolabelled Cyclic Bisarylmercury: High Chemical and in vivo Stability for Theranostics

Gilpin, I. M.; Ullrich, M.; Wünsche, T.; Zarschler, K.; Lebeda, O.; et al. (8 authors)

Guideline on current good radiopharmacy practice (cGRPP) for the small-scale preparation of radiopharmaceuticals

Gillings, N.; Hjelstuen, O.; Ballinger, J.; Béhé, M.; Decristoforo, C.; et al. (15 authors)

Polyoxometalates in Extraction and Sorption Processes

Jelinek, L.; Mištová, E.; Kubeil, M.; Stephan, H.

Effects of Acquisition Parameter Modifications and Field Strength on the Reproducibility of Brain Perfusion Measurements Using Arterial Spin-Labeling

Baas, K.; Petr, J.; Kuijer, J.; Nederveen, A.; Mutsaerts, H.-J.; et al. (6 authors)

  • American Journal of Neuroradiology 42(2021)1, 109-115
    Online First (2020) DOI: 10.3174/ajnr.A6856

GliMR: Cross-border collaborations to promote advanced MRI biomarkers in glioma

Clement, P.; Borovecki, F.; Emblem, K. E.; Figueiredo, P.; Hirschler, L.; et al. (14 authors)

A convolutional neural network for fully automated blood SUV determination to facilitate SUR computation in oncological FDG-PET

Nikulin, P.; Hofheinz, F.; Maus, J.; Li, Y.; Bütof, R.; et al. (11 authors)

  • Open Access Logo European Journal of Nuclear Medicine and Molecular Imaging 48(2021), 995-1004
    Online First (2020) DOI: 10.1007/s00259-020-04991-9

Studies on the affinity of 6-[(: N -(cyclo)aminoalkyl)oxy]-4 H -chromen-4-ones for sigma 1/2 receptors

Deuther-Conrad, W.; Diez-Iriepa, D.; Iriepa, I.; López-Muñoz, F.; Martínez-Grau, A. M.; et al. (7 authors)

Antihypertensive use differentially associated with lower cerebral blood flow in older people with hypertension

van Dalen, J. W.; Mutsaerts, H. J.; Petr, J.; Caan, M. W.; Moll Van Charante, E. P.; et al. (9 authors)

Clinical outcome of PSMA-guided radiotherapy for patients with oligorecurrent prostate cancer

Koerber, S. A.; Sprute, K.; Kratochwil, C.; Winter, E.; Haefner, M. F.; et al. (18 authors)

Dose dependent cerebellar atrophy in glioma patients after radio(chemo)therapy

Raschke, F.; Seidlitz, A.; Wesemann, T.; Löck, S.; Jentsch, C.; et al. (14 authors)

Sigma-1 and dopamine D2/D3 receptor occupancy of pridopidine in healthy volunteers and patients with Huntington disease: a [18F] fluspidine and [18F] fallypride PET study

Grachev, I.; Meyer, P.; Becker, G.; Bronzel, M.; Marsteller, D.; et al. (24 authors)

  • Open Access Logo European Journal of Nuclear Medicine and Molecular Imaging 48(2021), 1103-1115
    Online First (2020) DOI: 10.1007/s00259-020-05030-3

A modular, injectable, non-covalently assembled hydrogel system features widescale tunable degradability for controlled release and tissue integration

Rothe, R.; Xu, Y.; Kuriakose Thomas, A.; Meister, S.; Zhang, Y.; et al. (7 authors)

Highly sensitive silicon nanowire biosensor devices for the investigation of UniCAR platform in immunotherapy

Nguyen Le, T. A.; Sandoval Bojorquez, D. I.; Arnau, P. R.; Bergoi, I.; Feldmann, A.; et al. (8 authors)

The effects of intracranial stenosis on cerebral perfusion and cognitive performance

Hilal, S.; Mutsaerts, H. J. M. M.; Ferro, D. A.; Petr, J.; Kuijf, H.; et al. (7 authors)

(+)-[18F]Flubatine as a novel α4β2 nicotinic acetylcholine receptor PET ligand – Results of the first-in-human brain imaging application in patients with β-amyloid PET-confirmed Alzheimer’s disease and healthy controls

Tiepolt, S.; Becker, G.-A.; Wilke, S.; Cecchin, D.; Rullmann, M.; et al. (21 authors)

  • Open Access Logo European Journal of Nuclear Medicine and Molecular Imaging 48(2021), 731-746
    Online First (2020) DOI: 10.1007/s00259-020-05029-w

Hemodynamic impairments within individual watershed areas in asymptomatic carotid artery stenosis by multimodal MRI

Kaczmarz, S.; Goettler, J.; Petr, J.; Hansen, M. B.; Mouridsen, K.; et al. (8 authors)

2020

Preparation of 5‑[131I]iodotubercidin for the detection of adenosine kinase

Bier, D.; Holschbah, M.; Wedekind, F.; Sihver, W.; Drewes, B.; et al. (9 authors)

Telemedicine pre and post COVID-19: Lessons for commercialization based on previous use cases

Ferenczi, G. L.; Mahmood, A.; Bergmann, R.

  • Open Access Logo Journal of the International Society for Telemedicine and eHealth 8(2020), e8
    DOI: 10.29086/JISfTeH.8.e8

Suppression of Metastatic Melanoma Growth in Lung by Modulated Electro-Hyperthermia Monitored by a Minimally Invasive Heat Stress Testing Approach in Mice

Thomas, M. J.; Major, E.; Benedek, A.; Horvath, I.; Mathe, D.; et al. (9 authors)

Nanosensor-Based Real-Time Monitoring of Stress Biomarkers in Human Saliva Using a Portable Measurement System

Klinghammer, S.; Voitsekhivska, T.; Licciardello, N.; Kim, K.; Baek, C.-K.; et al. (10 authors)

PET measured hypoxia and MRI parameters in re-irradiated head and neck squamous cell carcinomas: findings of a prospective pilot study

Rogasch, J.; Beck, M.; Stromberger, C.; Hofheinz, F.; Ghadjar, P.; et al. (12 authors)

68Ga, 44Sc and 177Lu-labeled AAZTA5-PSMA-617: synthesis, radiolabeling, stability and cell binding compared to DOTA-PSMA-617 analogues

Sinnes, J.; Bauder-Wüst, U.; Schäfer, M.; Moon, E.; Kopka, K.; et al. (6 authors)

Comparative Studies of Light-Responsive Swimmers: Janus Nanorods versus Spherical Particles

Eichler-Volf, A.; Huang, T.; Vazquez Luna, F.; Alsaadawi, Y.; Stierle, S.; et al. (9 authors)

KRAS mutation effects on the 2-[18F]FDG PET uptake of colorectal adenocarcinoma metastases in the liver

Popovic, M.; Talarico, O.; van den Hoff, J.; Kunin, H.; Zhang, Z.; et al. (11 authors)

Short-duration dynamic FDG PET imaging: Optimization and clinical application

Samimi, R.; Kamali-Asl, A.; Geramifar, P.; van den Hoff, J.; Rahmim, A.

Asphericity of tumor FDG uptake in non-small cell lung cancer: Reproducibility and implications for harmonization in multicenter studies

Rogasch, J.; Furth, C.; Bluemel, S.; Radojewski, P.; Amthauer, H.; et al. (6 authors)

A FDG-PET radiomics signature detects esophageal squamous cell carcinoma patients who do not benefit from chemoradiation

Li, Y.; Beck, M.; Päßler, T.; Lili, C.; Wu, H.; et al. (17 authors)

Nanocytometer for smart analysis of peripheral blood and acute myeloid leukemia: a pilot study

Schütt, J.; Sandoval Bojorquez, D. I.; Avitabile, E.; Oliveros Mata, E. S.; Milyukov, G.; et al. (17 authors)

The pyrazolo[3,4-d]pyrimidine-based kinase inhibitor NVP-BHG712: Effects of regioisomers on tumor growth, perfusion, and hypoxia in EphB4-positive A375 melanoma xenografts

Neuber, C.; Tröster, A.; Löser, R.; Belter, B.; Schwalbe, H.; et al. (6 authors)

Electrochemical detection of ascorbic acid in artificial sweat using a flexible alginate/CuO-modified electrode

Ibarlucea, B.; Pérez, R. A.; Belyaev, D.; Baraban, L.; Cuniberti, G.

Development of PSMA-1007 - Related Series of 18F-Labeled Glu-ureido type PSMA inhibitors.

Cardinale, J.; Roscher, M.; Schaefer, M.; Geerlings, M.; Benešová, M.; et al. (13 authors)

Three-dimensional cell culture systems in radiopharmaceutical cancer research

Doctor, A.; Seifert, V.; Ullrich, M.; Hauser, S.; Pietzsch, J.

Prognostic value of baseline [18F]-fluorodeoxyglucose positron emission tomography parameters MTV, TLG and asphericity in an international multicenter cohort of nasopharyngeal carcinoma patients

Zschaeck, S.; Li, Y.; Lin, Q.; Beck, M.; Amthauer, H.; et al. (16 authors)

Applying tissue slice culture in cancer research—insights from preclinical proton radiotherapy

Suckert, T.; Rassamegevanon, T.; Müller, J.; Dietrich, A.; Graja, A.; et al. (10 authors)

In silico finding of key interaction mediated α3β4 and α7 nicotinic acetylcholine receptor ligand selectivity of quinuclidine-triazole chemotype

Arunrungvichian, K.; Chongruchiroj, S.; Sarasamkan, J.; Schüürmann, G.; Brust, P.; et al. (6 authors)

Live-cell Imaging with Aspergillus Fumigatus-specific fluorescent Siderophore Conjugates

Pfister, J.; Lichius, A.; Summer, D.; Haas, H.; Kanagasundaram, T.; et al. (7 authors)

HIF2α supports pro-metastatic behavior in pheochromocytomas/paragangliomas

Bechmann, N.; Moskopp, M. L.; Ullrich, M.; Calsina, B.; Wallace, P. W.; et al. (23 authors)

Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity

Gnad, T.; Navarro, G.; Lahesmaa, M.; Reverte-Salisa, L.; Copperi, F.; et al. (31 authors)

Rapidly Switchable Universal CAR-T Cells for Treatment of CD123-Positive Leukemia

Loff, S.; Dietrich, J.; Meyer, J.-E.; Riewaldt, J.; Spehr, J.; et al. (14 authors)

Development and In Vivo Application of a Water-Soluble Anticancer Copper Ionophore System Using a Temperature-Sensitive Liposome Formulation

Gaál, A.; Garay, T. M.; Horváth, I.; Máthé, D.; Szöllösi, D.; et al. (15 authors)

Inverse Solidification Induced by Active Janus Particles

Huang, T.; Misko, V. R.; Gobeil, S.; Wang, X.; Nori, F.; et al. (10 authors)

Intrinsic plasticity of silicon nanowire neurotransistors for dynamic memory and learning functions

Baek, E.; Ranjan Das, N.; Vittorio Cannistraci, C.; Rim, T.; Cañón Bermúdez, G. S.; et al. (14 authors)

Nanosensors-Assisted Quantitative Analysis of Biochemical Processes in Droplets

Belyaev, D.; Schütt, J.; Ibarlucea, B.; Rim, T.; Baraban, L.; et al. (6 authors)

Synthesis, characterization and evaluation of 68Ga labelled monomeric and dimeric quinazoline derivatives of the HBED-CC chelator targeting the epidermal growth factor receptor

Liolios, C.; Shegani, A.; Roupa, I.; Kiritsis, C.; Makarem, A.; et al. (11 authors)

Versatile chimeric antigen receptor platform for controllable and combinatorial T cell therapy

Feldmann, A.; Hoffmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; et al. (13 authors)

Combined tumor plus nontumor interim FDG‐PET parameters are prognostic for response to chemoradiation in squamous cell esophageal cancer

Zschaeck, S.; Li, Y.; Bütof, R.; Lili, C.; Hua, W.; et al. (15 authors)

Reconstructed spatial resolution and contrast recovery with Bayesian penalized likelihood reconstruction (Q.Clear) for FDG-PET compared to time-of-flight (TOF) with point spread function (PSF)

Rogasch, J.; Suleiman, S.; Hofheinz, F.; Bluemel, S.; Lukas, M.; et al. (7 authors)

Olfactory dysfunction correlates with putaminal dopamine turnover in early de novo Parkinson’s disease

Löhle, M.; Wolz, M.; Beuthien-Baumann, B.; Oehme, L.; van den Hoff, J.; et al. (8 authors)

The influence of different artificial extracellular matrix implant coatings on the regeneration of a critical size femur defect in rats

Förster, Y.; Schulze, S.; Penk, A.; Neuber, C.; Möller, S.; et al. (11 authors)

Recent insights in barium-131 as a diagnostic match for radium-223: cyclotron production, separation, labeling and imaging

Reissig, F.; Bauer, D.; Ullrich, M.; Kreller, M.; Pietzsch, J.; et al. (9 authors)

Metabolomics, machine learning and immunohistochemistry to predict succinate dehydrogenase mutational status in phaeochromocytomas and paragangliomas

Wallace, P. W.; Conrad, C.; Brückmann, S.; Pang, Y.; Caleiras, E.; et al. (26 authors)

Deuteration versus ethylation – strategies to improve the metabolic fate of a 18F-labeled celecoxib derivative

Laube, M.; Gassner, C.; Neuber, C.; Wodtke, R.; Ullrich, M.; et al. (12 authors)

A radiopharmacologist's and radiochemist's view on targeting the Eph/ephrin receptor tyrosine kinase system

Neuber, C.; Belter, B.; Mamat, C.; Pietzsch, J.

Individual patient data meta-analysis of FMISO and FAZA hypoxia PET scans from head and neck cancer patients undergoing definitive radio-chemotherapy

Zschaeck, S.; Löck, S.; Hofheinz, F.; Zips, D.; Mortensen, L.; et al. (17 authors)

Automated [18F]PSMA-1007 production by a single use cassette-type synthesizer for clinical examination

Naka, S.; Watabe, T.; Kurimoto, K.; Uemura, M.; Soeda, F.; et al. (14 authors)

Light-Activated Carbon Monoxide Prodrugs Based on Bipyridyl Dicarbonyl Ruthenium(II) Complexes

Geri, S.; Krunclova, T.; Janouskova, O.; Panek, J.; Hruby, M.; et al. (11 authors)

Adaptor CAR platforms - next generation of T cell-based cancer immunotherapy

Arndt, C.; Fasslrinner, F.; Loureiro, L. R.; Koristka, S.; Feldmann, A.; et al. (6 authors)

Surface Modification of Silicon Nanowire Based Field Effect Transistors with Stimuli Responsive Polymer Brushes for Biosensing Applications

Klinghammer, S.; Rauch, S.; Pregl, S.; Uhlmann, P.; Baraban, L.; et al. (6 authors)

Two‐Dimensional Boronate Ester Covalent Organic Framework Thin Films with Large Single Crystalline Domains for Neuromorphic Memory Device

Park, S.; Liao, Z.; Ibarlucea, B.; Qi, H.; Lin, H.-H.; et al. (19 authors)

Anisotropic exclusion effect between photocatalytic Ag/AgCl Janus particles and passive beads in a dense colloidal matrix

Huang, T.; Gobeil, S.; Wang, X.; Misko, V.; Nori, F.; et al. (10 authors)

Highly efficient targeting of EGFR-expressing tumor cells with UniCAR T cells via target modules based on Cetuximab®

Jureczek, J.; Feldmann, A.; Bergmann, R.; Arndt, C.; Berndt, N.; et al. (12 authors)

Extended half-life target module for sustainable UniCAR T-cell treatment of STn-expressing cancers

Loureiro, L. R.; Feldmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; et al. (11 authors)

Sigma-1 Receptor Positron Emission Tomography: A New Molecular Imaging Approach Using ( S)-(-)-[ 18 F]Fluspidine in Glioblastoma

Toussaint, M.; Deuther-Conrad, W.; Kranz, M.; Fischer, S.; Ludwig, F.-A.; et al. (11 authors)

Synthesis and evaluation of new 1-oxa-8-azaspiro[4.5]decane derivatives as candidate radioligands for sigma-1 receptors

Tian, J.; He, Y.; Deuther-Conrad, W.; Fu, H.; Xie, F.; et al. (12 authors)

Adjuvant drug-assisted bone healing: advances and challenges in drug delivery approaches

Rothe, R.; Hauser, S.; Neuber, C.; Laube, M.; Schulze, S.; et al. (7 authors)

Development of a radiofluorinated adenosine A2B receptor antagonist as potential ligand for PET imaging

Lindemann, M.; Moldovan, R.-P.; Hinz, S.; Deuther-Conrad, W.; Gündel, D.; et al. (13 authors)

Cation exchange protocols to radiolabel aqueous stabilized ZnS, ZnSe and CuFeS2 nanocrystals with 64Cu for dual radio- and photo-thermal therapy

Avellini, T.; Soni, N.; Silvestri, N.; Fiorito, S.; de Donato, F.; et al. (12 authors)

Development of novel analogs of the monocarboxylate transporter ligand FACH and biological validation of one potential radiotracer for PET imaging

Sadeghzadeh, M.; Wenzel, B.; Gündel, D.; Deuther-Conrad, W.; Toussaint, M.; et al. (13 authors)

Preclinical incorporation dosimetry of [18F]FACH - a novel 18F-labeled MCT1/MCT4 lactate transporter inhibitor for imaging cancer metabolism with PET

Sattler, B.; Kranz, M.; Wenzel, B.; Thachaantara Jain, N.; Moldovan, R.-P.; et al. (13 authors)

Rhenium and technetium-complexed silicon rhodamines as near-infrared imaging probes for bimodal SPECT- and optical imaging

Kanagasundaram, T.; Kramer, C. S.; Boros, E.; Kopka, K.

UniCAR T cell immunotherapy enables efficient elimination of radioresistant cancer cells

Arndt, C.; Loureiro, L. R.; Feldmann, A.; Jureczek, J.; Bergmann, R.; et al. (22 authors)

Contemporary Synthesis of Ultrasmall (sub-10 nm) Upconverting Nanomaterials

Joshi, T.; Mamat, C.; Stephan, H.

Rapid Thermodynamically Stable Complex Formation of [nat/111In]In3+, [nat/90Y]Y3+, and [nat/177Lu]Lu3+ with H6dappa

Kostelnik, T.; Xiaozhu, W.; Southcott, L. D.; Wagner, H.; Kubeil, M.; et al. (8 authors)

Chelation in One Fell Swoop: Optimizing Ligands for Smaller Radiometal Ions

Choudhary, N.; Jaraquemada-Pelaez, M.; Zarschler, K.; Wang, X.; Radchenko, V.; et al. (8 authors)

Accurate MR image registration to anatomical reference space for diffuse glioma

Visser, M.; Petr, J.; Müller, D. M.; Eijgelaar, R. S.; Hendriks, E. J.; et al. (12 authors)

Recombinant expression of ecto-nucleotide pyrophosphatase/phosphodiesterase 4 (NPP4) and development of a luminescence-based assay to identify inhibitors

Lopez, V.; Lee, S.-Y.; Stephan, H.; Müller, C. E.

Synthesis, radiolabeling and first biological characterization of 18F-labeled xanthine derivatives for PET imaging of Eph receptors

Pretze, M.; Neuber, C.; Kinski, E.; Belter, B.; Köckerling, M.; et al. (9 authors)

Regulation of bone regeneration

Jung, F.; Pietzsch, J.

  • Open Access Logo Clinical Hemorheology and Microcirculation 73(2020)3, 379-380
    DOI: 10.3233/CH-199101
    ISSN: 1386-0291

Carboranyl Derivatives of Rofecoxib with Cytostatic Activity Against Human Melanoma and Colon Cancer Cells

Buzharevski, A.; Paskas, S.; Sárosi, M.-B.; Laube, M.; Lönnecke, P.; et al. (11 authors)

The sigma-1 receptor: potential role in the modulation of cellular radiation sensitivity

Belter, B.; Deuther-Conrad, W.; Hofheinz, F.; Bachmann, M.; Brust, P.; et al. (6 authors)

“UniCAR”-modified off-the-shelf NK-92 cells for targeting of GD2-expressing tumour cells

Mitwasi, N.; Feldmann, A.; Arndt, C.; Koristka, S.; Berndt, N.; et al. (24 authors)

Interprofessionelle Kooperation in klinischen Studien. Zunehmender Bedarf, Komplexität und Anregungen am Beispiel einer prospektiv-onkologischen Multicenter-Studie.

Zippel, C.; Giesel, F.; Kopka, K.

Sub-10 nm Radiolabeled Barium Sulfate Nanoparticles as Carriers for Theranostic Applications and Targeted Alpha Therapy

Reissig, F.; Zarschler, K.; Hübner, R.; Pietzsch, H.-J.; Kopka, K.; et al. (6 authors)

Current status of PSMA-radiotracers for prostate cancer: data analysis of prospective trials listed on ClinicalTrials.gov

Zippel, C.; Ronski, S. C.; Bohnet-Joschko, S.; Giesel, F. L.; Kopka, K.

Radioimmunotherapy in Combination with Reduced-Intensity Conditioning for Allogeneic Hematopoietic Cell Transplantation in Patients with Advanced Multiple Myeloma

Fasslrinner, F.; Stölzel, F.; Kramer, M.; Teipel, R.; Brogsitter, C.; et al. (13 authors)

Cerebral Oxygen Metabolism in Adults with Sickle Cell Disease

Václavů, L.; Petr, J.; Petersen, E. T.; Mutsaerts, H. J. M. M.; Majoie, C. B. L.; et al. (9 authors)

Solution-Phase Synthesis of the Fluorogenic TGase 2 Acyl Donor Z-Glu(HMC)-Gly-OH and its Use for Inhibitor and Amine Substrate Characterisation

Wodtke, R.; Pietsch, M.; Löser, R.

Newly synthesized fluorinated cinnamylpiperazines possessing low in vitro MAO-B binding

Jevtić, I. I.; Lai, T. H.; Penjišević, J. Z.; Dukic-Stefanovic, S.; Andrić, D. B.; et al. (8 authors)

Active Targeting of Dendritic Polyglycerols for Diagnostic Cancer Imaging

Kritee, P.; Neuber, C.; Zarschler, K.; Wodtke, J.; Meister, S.; et al. (8 authors)

PET Imaging of the Adenosine A2A Receptor in the Rotenone-Based Mouse Model of Parkinson’s Disease with [18F]FESCH Synthesized by a Simplified Two-Step One-Pot Radiolabeling Strategy

Schröder, S.; Lai, T. H.; Toussaint, M.; Kranz, M.; Chovsepian, A.; et al. (13 authors)

Inhibition of ATP hydrolysis restores airway surface liquid production in cystic fibrosis airway epithelia

van Heusden, C.; Button, B.; Anderson, W. H.; Ceppe, A.; Morton, L. C.; et al. (12 authors)

ExploreASL: an image processing pipeline for multi-center ASL perfusion MRI studies

Mutsaerts, H. J.; Petr, J.; Groot, P. F.; Vandemaele, P.; Ingala, S.; et al. (42 authors)

Validation of an independent prognostic value of the asphericity of F18-fluorodeoxyglucose (FDG) uptake in non-small cell lung cancer (NSCLC) patients undergoing treatment in curative intent

Rogasch, J.; Furth, C.; Chibolela, C.; Hofheinz, F.; Ochsenreither, S.; et al. (11 authors)

The effect of hypoxia on the induction of strand breaks in plasmid DNA by alpha-, beta- and Auger electron-emitters 223Ra, 188Re, 99mTc and DNA-binding 99mTc-pyrene

Reissig, F.; Wunderlich, G.; Runge, R.; Freudenberg, R.; Lühr, A.; et al. (6 authors)

Versatile Bispidine-based Bifunctional Chelators for 64CuII-Labelling of Biomolecules

Singh, G.; Zarschler, K.; Hunoldt, S.; Santana Martinez, I. I.; Rühl, C.; et al. (12 authors)

Ultrasmall silicon nanoparticles as a promising platform for multimodal imaging

Singh, G.; Ddungu, J. L. Z.; Licciardello, N.; Bergmann, R.; de Cola, L.; et al. (6 authors)

Multi-modality bedding platform for combined imaging and irradiation of mice

Müller, J.; Schürer, M.; Neubert, C.; Tillner, F.; Beyreuther, E.; et al. (12 authors)

Spatial Coefficient of Variation of Arterial Spin Labeling MRI as a Cerebrovascular Correlate of Carotid Occlusive Disease

Mutsaerts, H. J. M. M.; Petr, J.; Bokkers, R. P. H.; Lazar, R. M.; Marshall, R. S.; et al. (6 authors)

Synthesis and Characterization of an Epidermal Growth Factor Receptor selective Ru(II) Polypyridyl-Nanobody Conjugate as a Photosensitizer for Photodynamic Therapy

Karges, J.; Jakubaszek, M.; Mari, C.; Zarschler, K.; Goud, B.; et al. (7 authors)

Cortical microinfarcts in memory clinic patients are associated with reduced cerebral perfusion

Ferro, D.; Mutsaerts, H.; Hilal, S.; Kuijf, H.; Petersen, E. T.; et al. (11 authors)

Formation of calix[4]arenes with acyloxycarboxylate functions

Bauer, D.; Stipurin, S.; Köckerling, M.; Mamat, C.

High-precision image-guided proton irradiation of mouse brain sub-volumes

Suckert, T.; Müller, J.; Beyreuther, E.; Bütof, R.; Dietrich, A.; et al. (12 authors)

2019

Correlation between FMISO-PET based hypoxia in the primary tumour and in lymph node metastases in locally advanced HNSCC patients

Bandurska-Luque, A.; Löck, S.; Haase, R.; Richter, C.; Zöphel, K.; et al. (14 authors)

The Evolving Landscape of Biomarkers for Anti-PD-1 or Anti-PD-L1 Therapy

Tunger, A.; Sommer, U.; Wehner, R.; Kubasch, A. S.; Grimm, M.-O.; et al. (10 authors)

Confirmation of the prognostic value of pretherapeutic tumor SUR and MTV in patients with esophageal squamous cell carcinoma

Hofheinz, F.; Li, Y.; Steffen, I.; Lin, Q.; Lili, C.; et al. (8 authors)

Introduction of the New Center for Radiopharmaceutical Cancer Research at Helmholtz-Zentrum Dresden-Rossendorf

Kreller, M.; Pietzsch, H.-J.; Walther, M.; Tietze, H.; Kaever, P.; et al. (9 authors)

Comparison of Static and Dynamic 18F-FDG PET/CT for Quantification of Pulmonary Inflammation in Acute Lung Injury

Braune, A.; Hofheinz, F.; Bluth, T.; Kiss, T.; Wittenstein, J.; et al. (8 authors)

Radiosynthesis and Biological Investigation of a Novel Fluorine-18 Labeled Benzoimidazotriazine- based Radioligand for Imaging of Phosphodiesterase 2A with Positron Emission Tomography

Ritawidya, R.; Wenzel, B.; Teodoro, R.; Toussaint, M.; Kranz, M.; et al. (10 authors)

Synthesis and cyclooxygenase inhibition of sulfonamide-substituted (dihydro)pyrrolo[3,2,1-hi]indoles and their potential prodrugs

Laube, M.; Gassner, C.; Knieß, T.; Pietzsch, J.

Characterization of Tissue Transglutaminase as a Potential Biomarker for Tissue Response toward Biomaterials

Hauser, S.; Wodtke, R.; Tondera, C.; Wodtke, J.; Neffe, A. T.; et al. (9 authors)

Synthesis, Structural Characterisation, and Cytotoxicity Studies of Bi, W, and Mo containing Homo- and Hetero-bimetallic Polyoxometalates

Senevirathna, D.; Werrett, M.; Kubeil, M.; Stephan, H.; Andrews, P.

Current management of pheochromocytoma/paraganglioma: A guide for the practicing clinician in the era of precision medicine

Nölting, S.; Ullrich, M.; Pietzsch, J.; Ziegler, C. G.; Eisenhofer, G.; et al. (7 authors)

Conventional CARs versus modular CARs

Feldmann, A.; Arndt, C.; Koristka, S.; Berndt, N.; Bergmann, R.; et al. (6 authors)

A comparative evaluation of calix[4]arene-1,3-crown-6 as a ligand for selected divalent cations of radiopharmaceutical interest

Bauer, D.; Blumberg, M.; Köckerling, M.; Mamat, C.

One-step radiosynthesis of the MCTs imaging agent [18F]FACH by aliphatic 18F-labelling of a methylsulfonate precursor containing an unprotected carboxylic acid group

Sadeghzadeh, M.; Moldovan, R.-P.; Teodoro, R.; Brust, P.; Wenzel, B.

A theranostic PSMA ligand for PET imaging and retargeting of T cells expressing the universal chimeric antigen receptor UniCAR

Arndt, C.; Feldmann, A.; Koristka, S.; Schäfer, M.; Bergmann, R.; et al. (19 authors)

Biomaterials in repairing rat femoral defects: in vivo insights from small animal positron emission tomography/computed tomography (PET/CT) studies

Neuber, C.; Schulze, S.; Förster, Y.; Hofheinz, F.; Wodke, J.; et al. (11 authors)

  • Open Access Logo Clinical Hemorheology and Microcirculation 73(2019), 177-194
    DOI: 10.3233/CH-199208

Structure–Affinity Relationships of Fluorinated Spirocyclic Sigma2 Receptor Ligands with an Exocyclic Benzylamino Moiety

Bergkemper, M.; Kronenberg, E.; Schepmann, D.; Ludwig, F.-A.; Brust, P.; et al. (6 authors)

¹⁸F-Labeled benzylpiperazine derivatives as highly selective ligands for imaging σ1 receptor with positron emission tomography

Ye, J.; Wang, L.; Deuther-Conrad, W.; Chen, Y.; Zhang, X.; et al. (9 authors)

  • Journal of Labelled Compounds and Radiopharmaceuticals 62(2019)8, 425-437
    DOI: 10.1002/jlcr.3738

Theranostic CAR T cell targeting: A brief review

Arndt, C.; Bachmann, M.; Bergmann, R.; Berndt, N.; Feldmann, A.; et al. (6 authors)

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 62(2019)8, 533-540
    DOI: 10.1002/jlcr.3727

Dual-time-point 64Cu-PSMA-617-PET/CT in patients suffering from prostate cancer

Hoberück, S.; Wunderlich, G.; Michler, E.; Hölscher, T.; Walther, M.; et al. (9 authors)

  • Journal of Labelled Compounds and Radiopharmaceuticals 62(2019)8, 523-532
    DOI: 10.1002/jlcr.3745

Tetranuclear Cu(II)-chiral complexes: Synthesis, characterization and biological activity

Peewasan, K.; Merkel, M. P.; Zarschler, K.; Stephan, H.; Anson, C. E.; et al. (6 authors)

The association of intra-therapeutic heterogeneity of somatostatin receptor expression with morphological treatment response in patients undergoing PRRT with [177Lu]-DOTATATE

Wetz, C.; Genseke, P.; Apostolova, I.; Furth, C.; Ghazzawi, S.; et al. (11 authors)

Instant kit preparation of 68Ga-radiopharmaceuticals via the hybrid chelator DATA: clinical translation of [68Ga]Ga-DATA-TOC

Sinnes, J. P.; Nagel, J.; Waldron, B. P.; Maina, T.; Nock, B. A.; et al. (11 authors)

Cytocompatible, Injectable, and Electroconductive Soft Adhesives with Hybrid Covalent/Noncovalent Dynamic Network

Xu, Y.; Patsis, P. A.; Hauser, S.; Voigt, D.; Rothe, R.; et al. (15 authors)

Editorial for special issue "Jörg Steinbach"

Mamat, C.

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 62(2019)8, 350-351
    DOI: 10.1002/jlcr.3773

T cells engrafted with a UniCAR 28/ζ outperform UniCAR BB/ζ-transduced T cells in the face of regulatory T cell-mediated immunosuppression

Kegler, A.; Koristka, S.; Bergmann, R.; Berndt, N.; Arndt, C.; et al. (10 authors)

Nitric oxide-releasing selective estrogen receptor modulators (NO-SERMs): a bifunctional approach to improve the therapeutic index

Bechmann, N.; Knieß, T.; Pietzsch, J.

Targeting Cyclooxygenase-2 in Pheochromocytoma and Paraganglioma: Focus on Genetic Background

Ullrich, M.; Richter, S.; Seifert, V.; Hauser, S.; Calsina, B.; et al. (12 authors)

Synthesis and in vitro evaluation of 8-pyridinyl substituted benzo[e]imidazo[2,1-c][1,2,4]triazines as phosphodiesterase 2A (PDE2A) inhibitors

Ritawidya, R.; Ludwig, F.-A.; Briel, D.; Brust, P.; Scheunemann, M.

Adjuvant drug-assisted bone healing: Part III – Further strategies for local and systemic modulation

Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; et al. (6 authors)

  • Clinical Hemorheology and Microcirculation 73(2019), 439-488
    DOI: 10.3233/CH-199104
    ISSN: 1386-0291

Adjuvant drug-assisted bone healing: Part II – Modulation of angiogenesis

Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; et al. (6 authors)

  • Open Access Logo Clinical Hemorheology and Microcirculation 73(2019), 409-438
    DOI: 10.3233/CH-199103
    ISSN: 1386-0291

Adjuvant drug-assisted bone healing: Part I – Modulation of inflammation

Rothe, R.; Schulze, S.; Neuber, C.; Hauser, S.; Rammelt, S.; et al. (6 authors)

  • Clinical Hemorheology and Microcirculation 73(2019), 381-408
    DOI: 10.3233/CH-199102
    ISSN: 1386-0291

The UniCAR system: A modular CAR T cell approach to improve the safety of CAR T cells

Bachmann, M.

Impact of Extrinsic and Intrinsic Hypoxia on Catecholamine Biosynthesis in Absence or Presence of Hif2α in Pheochromocytoma Cells

Bechmann, N.; Poser, I.; Seifert, V.; Greunke, C.; Ullrich, M.; et al. (13 authors)

Carboranyl analogues of ketoprofen with cytostatic activity against human melanoma and colon cancer cell lines

Buzharevski, A.; Paskas, S.; Laube, M.; Lönnecke, P.; Neumann, W.; et al. (10 authors)

Midostaurin abrogates CD33-directed UniCAR and CD33-CD3 bispecific antibody therapy in acute myeloid leukemia

Fasslrinner, F.; Arndt, C.; Koristka, S.; Feldmann, A.; Altmann, H.; et al. (9 authors)

An oligo-His-tag of a targeting module does not influence its biodistribution and the retargeting capabilities of UniCAR T cells

Jureczek, J.; Bergmann, R.; Berndt, N.; Koristka, S.; Kegler, A.; et al. (10 authors)

Late life brain perfusion after prenatal famine exposure

de Rooij, S. R.; Mutsaerts, H. M.; Petr, J.; Asllani, I.; Caan, M. W.; et al. (9 authors)

A 224Ra-labeled polyoxopalladate as putative radiopharmaceutical

Gott, M.; Yang, P.; Kortz, U.; Stephan, H.; Pietzsch, H.-J.; et al. (6 authors)

Interobserver variability of image-derived arterial blood SUV in whole-body FDG PET

Hofheinz, F.; Maus, J.; Zschaeck, S.; Rogasch, J.; Schramm, G.; et al. (9 authors)

Time efficient scatter correction for time-of-flight PET: the immediate scatter approximation

Nikulin, P.; Maus, J.; Hofheinz, F.; Lougovski, A.; van den Hoff, J.

SPECT-Untersuchungen mit dem 123 I-markierten Dopamintransporter-Liganden FP-CIT (DaTSCAN):DGN-Handlungsempfehlung (S1-Leitlinie)

Tatsch, K.; Buchert, R.; Bartenstein, P.; Barthel, H.; Boecker, H.; et al. (17 authors)

  • Nuklearmedizin 58(2019)1, 5-16

In vitro and in vivo Human Metabolism of (S)-[18F]Fluspidine – a Radioligand for Imaging σ1 Receptors with Positron Emission Tomography (PET)

Ludwig, F.-A.; Fischer, S.; Houska, R.; Hoepping, A.; Deuther-Conrad, W.; et al. (15 authors)

Limited importance of EphrinA1–ligand, Src kinase, and focal adhesion kinase in EphA2-mediated regulation of metastasis in Mel-Juso and A375 human melanoma cells

Neuber, C.; Herwig, N.; Pietzsch, J.; Belter, B.

  • Journal of Cellular Biotechnology 5(2019)1, 11-26
    DOI: 10.3233/JCB-189010
    ISSN: 2352-3689

Regulation of A375 melanoma cell adhesion and migration by EphB4 and EphrinB2 –insights from co-culture experiments

Neuber, C.; Laube, M.; Mamat, C.; Belter, B.; Pietzsch, J.

  • Journal of Cellular Biotechnology 5(2019)1, 27-42
    DOI: 10.3233/JCB-189011
    ISSN: 2352-3689

Radiochemical and radiopharmacological characterization of a 64Cu-labeled α-MSH analog conjugated with different chelators

Gao, F.; Sihver, W.; Bergmann, R.; Walther, M.; Stephan, H.; et al. (11 authors)

  • Journal of Labelled Compounds and Radiopharmaceuticals 62(2019)8, 495-509
    DOI: 10.1002/jlcr.3728

Fluorescent Mouse Pheochromocytoma Spheroids Expressing Hypoxia-Inducible Factor 2 alpha: Morphologic and Radiopharmacologic Characterization

Seifert, V.; Liers, J.; Kniess, T.; Richter, S.; Bechmann, N.; et al. (10 authors)

  • Journal of Cellular Biotechnology 5(2019)2, 135-151
    DOI: 10.3233/JCB-199005
    ISSN: 2352-3689

Facile preparation of radium-doped, functionalized nanoparticles as carriers for targeted alpha therapy

Reissig, F.; Hübner, R.; Steinbach, J.; Pietzsch, H.-J.; Mamat, C.

Carboranyl Analogues of Celecoxib with Potent Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines

Buzharevski, A.; Paskas, S.; Sárosi, M. B.; Laube, M.; Lönnecke, P.; et al. (10 authors)

Fluorine-18 labeling of S100 proteins for small animal positron emission tomography

Laube, M.; Kniess, T.; Neuber, C.; Haase-Kohn, C.; Pietzsch, J.

Development and radiosynthesis of the first 18F-labeled inhibitor of monocarboxylate transporters (MCTs)

Sadeghzadeh, M.; Moldovan, R.-P.; Fischer, S.; Wenzel, B.; Ludwig, F.-A.; et al. (14 authors)

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 62(2019)8, 411-424
    DOI: 10.1002/jlcr.3739

FDG-PET/MRI in patients with pelvic recurrence of rectal cancer: first clinical experiences

Plodeck, V.; Rahbari, N.; Weitz, J.; Radosa, C.; Laniado, M.; et al. (11 authors)

Synthesis, Structural Characterization and Photodecarbonylation Study of a Dicarbonyl Ruthenium(II)-Bisquinoline Complex

Kubeil, M.; Joshi, T.; Wood, B. R.; Stephan, H.

Synthesis and preliminary radiopharmacological characterisation of an 11C-labelled azadipeptide nitrile as potential PET tracer for imaging of cysteine cathepsins

Laube, M.; Frizler, M.; Wodtke, R.; Neuber, C.; Belter, B.; et al. (10 authors)

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 62(2019)8, 448-459
    DOI: 10.1002/jlcr.3729

Tarnkappen-Technologie für leuchtende Nanopartikeln

Stephan, H.; Zarschler, K.

  • Open Access Logo GIT Labor-Fachzeitschrift (2019)8, 55-57

Tonic signaling and its effects on lymphopoiesis of CAR-armed hematopoietic stem and progenitor cells

Albert, S.; Koristka, S.; Gerbaulet, A.; Cartellieri, M.; Arndt, C.; et al. (15 authors)

Cerebral perfusion changes in presymptomatic genetic frontotemporal dementia: a GENFI study

Mutsaerts, H. J. M. M.; Mirza, S. S.; Petr, J.; Thomas, D. L.; Cash, D. M.; et al. (31 authors)

Targeting cyclic nucleotide phosphodiesterase 5 (PDE5) in brain: Toward the development of a PET radioligand labeled with fluorine-18

Wenzel, B.; Liu, J.; Dukic-Stefanovic, S.; Deuther-Conrad, W.; Teodoro, R.; et al. (10 authors)

Synthesis, 18F-labelling and radiopharmacological characterisation of the C-terminal 30mer of Clostridium perfringens enterotoxin as a potential claudin-targeting peptide

Löser, R.; Bader, M.; Kuchar, M.; Wodtke, R.; Lenk, J.; et al. (12 authors)

Neoadjuvant radiochemotherapy significantly alters the phenotype of plasmacytoid dendritic cells and 6-sulfo LacNAc+ monocytes in rectal cancer

Wagner, F.; Hölig, U.; Wilczkowski, F.; Sommer, U.; Wehner, R.; et al. (23 authors)

Cathepsin B: Active Site Mapping with Peptidic Substrates and Inhibitors

Schmitz, J.; Gilberg, E.; Löser, R.; Bajorath, J.; Bartz, U.; et al. (6 authors)

One-pot Cascade Synthesis of Pyrazole-based Isosteres of Valdecoxib by a [3+2] Cycloaddition/[1,5] Sigmatropic Rearrangement Sequence and Evaluation of their COX Inhibitory Activity

Roscales, S.; Bechmann, N.; Pietzsch, J.; Kniess, T.

Anti-CAR engineered T cells for epitope-based elimination of autologous CAR T cells

Koristka, S.; Ziller-Walter, P.; Bergmann, R.; Arndt, C.; Feldmann, A.; et al. (11 authors)

Access to 18F-labelled isoxazoles by Ruthenium-promoted 1,3-dipolar cycloaddition of 4-[18F]fluoro-N-hydroxybenzimidoyl chloride with alkynes.

Roscales, S.; Kniess, T.

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 62(2019), 393-403
    DOI: 10.1002/jlcr.3708

Expression of Glypican-3 is an Independent Prognostic Biomarker in Primary Gastro-Esophageal Adenocarcinoma and Corresponding Serum Exosomes

Rahbari, M.; Pecqueux, M.; Aust, D.; Stephan, H.; Tiebel, O.; et al. (14 authors)

Prognostic value of SUR in patients with trimodality treatment of locally advanced esophageal carcinoma

Bütof, R.; Hofheinz, F.; Zöphel, K.; Schmollack, J.; Jentsch, C.; et al. (9 authors)

Studies towards the development of a PET radiotracer for imaging of the P2Y1 receptors in the brain: synthesis, 18F-labeling and preliminary biological evaluation

Moldovan, R.-P.; Wenzel, B.; Teodoro, R.; Neumann, W.; Dukic-Stefanovic, S.; et al. (9 authors)

2018

Pretherapeutic FDG–PET total metabolic tumor volume predicts response to induction therapy in pediatric Hodgkin’s lymphoma

Rogasch, J.; Hundsdoerfer, P.; Hofheinz, F.; Wedel, F.; Schatka, I.; et al. (7 authors)

Evaluation of Brain Nuclear Medicine Imaging Tracers in a Murine Model of Sepsis-Associated Encephalopathy

Szöllősi, D.; Hegedűs, N.; Veres, D. S.; Futó, I.; Horváth, I.; et al. (15 authors)

Immune Monitoring of Cancer Patients Prior to and During CTLA-4 or PD-1/PD-L1 Inhibitor Treatment

Tunger, A.; Kießler, M.; Wehner, R.; Temme, A.; Meier, F.; et al. (7 authors)

Multimodal PET/MRI Imaging Results Enable Monitoring the Side Effects of Radiation Therapy.

Kovács, N.; Szigeti, K.; Hegedűs, N.; Horváth, I.; Veres, D. S.; et al. (8 authors)

In vivo confirmation of altered hepatic glucose metabolism in patients with liver fibrosis/cirrhosis by 18F-FDG PET/CT

Verloh, N.; Einspieler, I.; Utpatel, K.; Menhart, K.; Brunner, S.; et al. (12 authors)

Synthesis, Receptor Affinity, and Antiallodynic Activity of Spirocyclic σ Receptor Ligands with Exocyclic Amino Moiety

Bergkemper, M.; Kronenberg, E.; Thum, S.; Börgel, F.; Daniliuc, C.; et al. (11 authors)

Diverse Effects of Phospholipase A2 Receptor Expression on LNCaP and PC-3 Prostate Cancer Cell Growth in vitro and in vivo

Friedemann, M.; Nacke, B.; Hagelgans, A.; Jandeck, C.; Bechmann, N.; et al. (11 authors)

Towards Utilising Photocrosslinking of Polydiacetylenes for the Preparation of “Stealth” Upconverting Nanoparticles

Nsubuga, A.; Zarschler, K.; Sgarzi, M.; Graham, B.; Stephan, H.; et al. (6 authors)

Improved Conjugation, 64-Cu Radiolabeling, in Vivo Stability, and Imaging Using Nonprotected Bifunctional Macrocyclic Ligands: Bis(Phosphinate) Cyclam (BPC) Chelators

David, T.; Hlinová, V.; Kubíček, V.; Bergmann, R.; Striese, F.; et al. (12 authors)

Fourier Analysis of Cerebral Metabolism of Glucose: Gender Differences in Mechanisms of Color Processing in the Ventral and Dorsal Streams in Mice

Njemanze, P. C.; Kranz, M.; Brust, P.

NMR-based investigations of acyl-functionalized piperazines concerning their conformational behavior in solution

Steinberg, J.; Köckerling, M.; Wodtke, R.; Löser, R.; Mamat, C.

Synthesis, characterization and initial biological evaluation of [⁹⁹ᵐTc]Tc-tricarbonyl labeled DPA-α-MSH peptide derivatives for potential melanoma imaging

Gao, F.; Sihver, W.; Bergmann, R.; Belter, B.; Bolzati, C.; et al. (9 authors)

Exploring pitfalls of 64Cu‑labeled EGFR‑targeting peptide GE11 as a potential PET tracer

Striese, F.; Sihver, W.; Gao, F.; Bergmann, R.; Walther, M.; et al. (8 authors)

Development of a novel target module redirecting UniCAR T cells to Sialyl Tn-expressing tumor cells

Loureiro, L.; Feldmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; et al. (10 authors)

Strain-specific metastatic phenotypes in pheochromocytoma allograft mice

Ullrich, M.; Liers, J.; Peitzsch, M.; Feldmann, A.; Bergmann, R.; et al. (12 authors)

Development of a selective and highly sensitive fluorescence assay for nucleoside triphosphate diphosphohydrolase1 (NTPDase1, CD39)

Lee, S.-Y.; Luo, X.; Namasivayam, V.; Geiss, J.; Mirza, S.; et al. (9 authors)

Cerebrovascular Reactivity during Prolonged Breath-Hold in Experienced Freedivers

Keil, V.; Eichhorn, L.; Mutsaerts, H.; Träber, F.; Block, W.; et al. (13 authors)

Contilisant, a Tetratarget Small Molecule for Alzheimer’s Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition and H3R Antagonism with Sigma 1R Agonism Profile

Bautista-Aguilera, O. M.; Budni, J.; Mina, F.; Medeiros, E. B.; Deuther-Conrad, W.; et al. (10 authors)

From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo

Albert, S.; Arndt, C.; Koristka, S.; Berndt, N.; Bergmann, R.; et al. (10 authors)

Cognitive correlates of α4β2 nicotinic acetylcholine receptors in mild Alzheimer's dementia

Sabri, O.; Meyer, P. M.; Gräf, S.; Hesse, S.; Wilke, S.; et al. (21 authors)

Radiosynthesis and in vivo evaluation of a fluorine-18 labeled pyrazine based radioligand for PET imaging of the adenosine A2B receptor

Lindemann, M.; Hinz, S.; Deuther-Conrad, W.; Namasivayam, V.; Dukic-Stefanovic, S.; et al. (13 authors)

Monitoring scanner calibration using the image derived arterial blood SUV in whole-body FDG-PET

Maus, J.; Hofheinz, F.; Apostolova, I.; Kreissl, M. C.; Kotzerke, J.; et al. (6 authors)

Increased evidence for the prognostic value of late-treatment FDG-PET uptake in non-tumor affected oesophagus in irradiated patients with oesophageal carcinomas

Li, Y.; Hofheinz, F.; Furth, C.; Lili, C.; Hua, W.; et al. (7 authors)

Effects of systematic partial volume errors on the computation of mean gray matter cerebral blood flow with Arterial Spin Labeling MRI

Petr, J.; Mutsaerts, H. J. M. M.; de Vita, E.; Steketee, R. M. E.; Smits, M.; et al. (9 authors)

Preyssler-Pope-Jeannin Polyanions [NaP5W30O110]14- and [AgP5W30O110]14-: Synthesis, Structural Characterization, Electrochemistry, Antiproliferative and Antibacterial Activity

Haider, A.; Zarschler, K.; Joshi, S. A.; Smith, R.; Lin, Z.; et al. (10 authors)

Synthesis and radiofluorination of novel fluoren-9-one based derivatives for the imaging of α7 nicotinic acetylcholine receptor with PET

Teodoro, R.; Scheunemann, M.; Wenzel, B.; Peters, D.; Deuther-Conrad, W.; et al. (6 authors)

Molekulare Bildgebung in der Onkologie mittels Positronen-Emissions-Tomographie

Derlin, T.; Grünwald, V.; Steinbach, J.; Wester, H.-J.; Ross, T. L.

Harnessing the Coordination Chemistry of 1,4,7-Triazacyclononane for Biomimicry and Radiopharmaceutical Applications

Joshi, T.; Kubeil, M.; Nsubuga, A.; Singh, G.; Gasser, G.; et al. (6 authors)

Clinical translation and regulatory aspects of CAR/TCR-based adoptive cell therapies-the German Cancer Consortium approach.

Krackhardt, A. M.; Anliker, B.; Hildebrandt, M.; Bachmann, M.; Eichmüller, S. B.; et al. (12 authors)

Nε-Acryloyllysine piperazides as irreversible inhibitors of transglutaminase 2 – synthesis, structure-activity relationships and pharmacokinetic profiling

Wodtke, R.; Hauser, C.; Ruiz-Gómez, G.; Jäckel, E.; Bauer, D.; et al. (16 authors)

Biodistribution studies of ultrasmall silicon nanoparticles and carbon dots in experimental rats and tumor mice

Licciardello, N.; Hunoldt, S.; Bergmann, R.; Singh, G.; Mamat, C.; et al. (11 authors)

Overexpression of receptor tyrosine kinase EphB4 triggers tumor growth and hypoxia in A375 melanoma xenografts: insights from multitracer small animal imaging experiments

Neuber, C.; Belter, B.; Meister, S.; Hofheinz, F.; Bergmann, R.; et al. (7 authors)

Modified Calix[4]crowns as Molecular Receptors for Barium

Steinberg, J.; Bauer, D.; Reissig, F.; Köckerling, M.; Pietzsch, H.-J.; et al. (6 authors)

Exploring the Metabolism of (+)-[18F]Flubatine in vitro and in vivo: LC-MS/MS aided Identification of Radiometabolites in a Clinical PET Study

Ludwig, F.-A.; Fischer, S.; Smits, R.; Deuther-Conrad, W.; Hoepping, A.; et al. (9 authors)

Facile Preparation of Multifunctionalisable ‘Stealth’ Upconverting Nanoparticles for Biomedical Applications

Nsubuga, A.; Sgarzi, M.; Zarschler, K.; Kubeil, M.; Hübner, R.; et al. (9 authors)

Investigation of an 18F-labelled Imidazopyridotriazine for Molecular Imaging of Cyclic Nucleotide Phosphodiesterase 2A

Schröder, S.; Wenzel, B.; Deuther-Conrad, W.; Teodoro, R.; Kranz, M.; et al. (11 authors)

Bridging from Brain to Tumor imaging: (S)- and (R)-[18F]Fluspidine for investigation of Sigma-1 Receptors in Tumor-bearing Mice

Kranz, M.; Bergmann, R.; Kniess, T.; Belter, B.; Neuber, C.; et al. (14 authors)

Spectroscopic Studies on Photoinduced Reactions of the Anticancer Prodrug, trans,trans,trans-[Pt(N3)2(OH)2(py)2]

Vernooij, R. R.; Joshi, T.; Horbury, M. D.; Graham, B.; Izgorodina, E. I.; et al. (9 authors)

Causative treatment of acid aspiration induced acute lung injury – recent trends from animal experiments and critical perspective

Gramatté, J.; Pietzsch, J.; Bergmann, R.; Richter, T.

  • Open Access Logo Clinical Hemorheology and Microcirculation 69(2018), 187-195
    DOI: 10.3233/CH-189113
    ISSN: 1386-0291

Engrafting human regulatory T cells with a flexible modular chimeric antigen receptor technology

Koristka, S.; Kegler, A.; Bergmann, R.; Arndt, C.; Feldmann, A.; et al. (17 authors)

Rapid synthesis of sub-10 nm hexagonal NaYF4-based upconverting nanoparticles using Therminol 66

Hesse, J.; Klier, D. T.; Sgarzi, M.; Nsubuga, A.; Bauer, C.; et al. (11 authors)

Photon vs. proton radiochemotherapy: effects on brain tissue volume and perfusion

Petr, J.; Platzek, I.; Hofheinz, F.; Mutsaerts, H.; Asllani, I.; et al. (16 authors)

Chelation of heavy group 2 (radio)metals by p-tert-butylcalix[4]arene-1,3-crown-6 and logK determination via NMR

Bauer, D.; Gott, M.; Steinbach, J.; Mamat, C.

Evaluation of fluorine-18-labelled alpha1(I)-N-telopeptide analogues as substrate-based radiotracers for PET imaging of melanoma-associated lysyl oxidase

Kuchar, M.; Neuber, C.; Belter, B.; Bergmann, R.; Lenk, J.; et al. (10 authors)

Facile Silylation of Cyclitols using Silyl-bis(triflates)

Topp, A.; Köckerling, M.; Reinke, H.; Miethchen, R.; Mamat, C.

Comparison of arterial spin labeling registration strategies in the multi-center GENetic frontotemporal dementia initiative (GENFI)

Mutsaerts, H. J. M. M.; Petr, J.; Thomas, D. L.; de Vita, E.; Cash, D. M.; et al. (23 authors)

  • Open Access Logo Journal of Magnetic Resonance Imaging 47(2018)1, 131-140
    Online First (2017) DOI: 10.1002/jmri.25751

A Bayesian Approach for Measurements of Stray Neutrons at Proton Therapy Facilities: Quantifying Neutron Dose Uncertainty

Dommert, M.; Reginatto, M.; Zboril, M.; Fiedler, F.; Helmbrecht, S.; et al. (7 authors)

  • Radiation Protection Dosimetry 180(2018)1-4, 319-323
    Online First (2017) DOI: 10.1093/rpd/ncx264

Recent Progress using the Staudinger Ligation for Radiolabeling Applications

Mamat, C.; Gott, M.; Steinbach, J.

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 61(2018), 165-178
    DOI: 10.1002/jlcr.3562

Novel Valdecoxib Derivates by Ruthenium-catalyzed 1,3-Dipolar Cycloaddition of Nitrile Oxides with Alkynes - Synthesis and COX-2 Inhibition Affinity.

Roscales, S.; Bechmann, N.; Weiss, D. H.; Köckerling, M.; Pietzsch, J.; et al. (6 authors)

Structural and kinetic considerations for the application of the traceless Staudinger ligation to future 18F radiolabeling using XRD and 19F-NMR

Köckerling, M.; Mamat, C.

2017

Synthesis and Pharmacological Evaluation of Identified and Putative Metabolites of the A₁ Adenosine Receptor Antagonist 8-Cyclopentyl-3-(3-fluoropropyl)-1-propylxanthine (CPFPX)

Holschbach, M. H.; Bier, D.; Sihver, W.; Schulze, A.; Neumaier, B.

Quantification: there is more to worry about than good scanner hardware and reliable calibration

Kotzerke, J.; van den Hoff, J.

  • European Journal of Nuclear Medicine and Molecular Imaging 44(2017)12, 1955-1957
    DOI: 10.1007/s00259-017-3808-z
    ISSN: 1619-7089

Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment

Mattei, D.; Ivanov, A.; Ferrai, C.; Jordan, P.; Guneykaya, D.; et al. (21 authors)

An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment

Huebner, D.; Rieger, C.; Bergmann, R.; Ullrich, M.; Meister, S.; et al. (13 authors)

Nitric oxide-releasing selective cyclooxygenase-2 inhibitors as promising radiosensitizers in melanoma cells in vitro

Bechmann, N.; Hauser, S.; Hofheinz, F.; Kniess, T.; Pietzsch, J.

  • Open Access Logo Annals of Radiation Therapy and Oncology 1(2017)2, 1010

Potential of asphericity as a novel diagnostic parameter in the evaluation of patients with Ga-68-PSMA-HBED-CC PET-positive prostate cancer lesions

Meissner, S.; Janssen, J.; Prasad, V.; Brenner, W.; Diederichs, G.; et al. (8 authors)

Exploratory investigation of PSCA-protein expression in primary breast cancer patients reveals a link to HER2/neu overexpression.

Link, T.; Kuithan, F.; Ehninger, A.; Kuhlmann, J. D.; Kramer, M.; et al. (13 authors)

Mass spectrometry-based identification of a naturally presented receptor tyrosine kinase-like orphan receptor 1-derived epitope recognized by CD8+ cytotoxic T cells

Heidenreich, F.; Rücker-Braun, E.; Walz, J. S.; Eugster, A.; Kühn, D.; et al. (22 authors)

Novel Radiolabeled Bisphosphonates for PET Diagnosis and Endoradiotherapy of Bone Metastases

Pfannkuchen, N.; Meckel, M.; Bergmann, R.; Bachmann, M.; Bal, C.; et al. (9 authors)

Biological characterization of novel nitroimidazole-peptide conjugates in vitro and in vivo.

Bergmann, R.; Splith, K.; Pietzsch, J.; Bachmann, M.; Neundorf, I.

Characterization of a switchable chimeric antigen receptor platform in a pre-clinical solid tumor model

Bejestani, E. P.; Cartellieri, M.; Bergmann, R.; Ehninger, A.; Loff, S.; et al. (17 authors)

Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells

Bachmann, D.; Aliperta, R.; Bergmann, R.; Feldmann, A.; Koristka, S.; et al. (19 authors)

Preparation of 18F-labeled building blocks for peptide conjugation using the "minimalist" approach

Omrane, M. A.; Zlatopolskiy, B. D.; Urusova, E.; Mamat, C.; Feni, L.; et al. (7 authors)

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S261
    DOI: 10.1002/jlcr.3508

Evaluation of Ba/Ra Polyoxopalladates for Radiopharmaceutical Applications

Gott, M.; Yang, P.; Kortz, U.; Pietzsch, H.-J.; Steinbach, J.; et al. (6 authors)

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S559
    DOI: 10.1002/jlcr.3508

Novel Functionalized Calixarenes as Host Molecules for Complexation with Alkaline Earth Metals

Steinberg, J.; Gott, M.; Pietzsch, H.-J.; Steinbach, J.; Mamat, C.

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S488
    DOI: 10.1002/jlcr.3508

Detection of Auger Electron Induced Strand Breaks on Plasmid DNA Caused by Technetium-99m Labeled Pyrene Derivatives

Wunderlich, G.; Reissig, F.; Mamat, C.; Pietzsch, H.-J.; Kotzerke, J.; et al. (6 authors)

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S365
    DOI: 10.1002/jlcr.3508

Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells

Mitwasi, N.; Feldmann, A.; Bergmann, R.; Berndt, N.; Arndt, C.; et al. (17 authors)

Synthesis and X-ray Crystal Structure of N’-Cyano-N,N’-dimethyl-4-nitrobenzohydrazide

Löser, R.; Pitzschler, R.; Köckerling, M.

Individualized risk assessment in neuroblastoma: does the tumoral metabolic activity on 123I-MIBG SPECT predict the outcome?

Rogasch, J.; Hundsdoerfer, P.; Furth, C.; Wedel, F.; Hofheinz, F.; et al. (11 authors)

Increased FDG uptake on late-treatment PET in non-tumour-affected oesophagus is prognostic for pathological complete response and disease recurrence in patients undergoing neoadjuvant radiochemotherapy

Zschaeck, S.; Hofheinz, F.; Zöphel, K.; Bütof, R.; Jentsch, C.; et al. (12 authors)

PET Imaging Evaluation of Four sigma1 Radiotracers in Nonhuman Primates

Baum, E.; Cai, Z.; Bois, F.; Holden, D.; Lin, S.-F.; et al. (16 authors)

1‑(4‑[18F]Fluorobenzyl)-4-[(tetrahydrofuran-2-yl)methyl]piperazine: A Novel Suitable Radioligand with Low Lipophilicity for Imaging σ1 Receptors in the Brain

He, Y.; Xie, F.; Ye, J.; Deuther-Conrad, W.; Cui, B.; et al. (12 authors)

18F-Labeled indole-based analogs as highly selective radioligands for imaging sigma-2 receptors in the brain

Wang, L.; Ye, J.; He, Y.; Deuther-Conrad, W.; Zhang, J.; et al. (11 authors)

99mTechnetium-based Small Molecule Radiopharmaceuticals and Radiotracers Targeting Inflammation and Infection

Kniess, T.; Laube, M.; Wüst, F.; Pietzsch, J.

Test-retest variability of lesion SUV and lesion SUR in 18F-FDG PET: an analysis of data from two prospective multicenter trials

Hofheinz, F.; Apostolova, I.; Oehme, L.; Kotzerke, J.; van den Hoff, J.

FDG PET/MR in initial staging of sarcoma: Initial experience and comparison with conventional imaging

Platzek, I.; Beuthien-Baumann, B.; Schramm, G.; Maus, J.; Laniado, M.; et al. (8 authors)

Studies of carbon monoxide release from ruthenium(II) bipyridine carbonyl complexes upon UV light exposure

Kubeil, M.; Vernooij, R. R.; Kubeil, C.; Wood, B. R.; Graham, B.; et al. (7 authors)

Expression of ecto-nucleoside triphosphate diphosphohydrolases-2 and -3 by the enteric nervous system impacts inflammation in experimental colitis and Crohn’s disease

Feldbrügge, L.; Moss, A. C.; Yee, E. U.; Csizmadia, E.; Mitsuhashi, S.; et al. (13 authors)

Synthesis and in vitro evaluation of 5-substituted benzovesamicol analogs containing N-substituted amides as potential positron emission tomography tracers for the vesicular acetylcholine transporter

Roslin, S.; de Rosa, M.; Deuther-Conrad, W.; Eriksson, J.; Odell, L. R.; et al. (8 authors)

Radiosynthesis of (S)-[18F]T1: The first PET radioligand for molecular imaging of α3β4 nicotinic acetylcholine receptors

Sarasamkan, J.; Fischer, S.; Deuther-Conrad, W.; Ludwig, F.-A.; Scheunemann, M.; et al. (8 authors)

Preparation of a novel radiotracer targeting the EphB4 receptor via radiofluorination using spiro azetidinium salts as precursor

Wiemer, J.; Steinbach, J.; Pietzsch, J.; Mamat, C.

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017), 489-498
    DOI: 10.1002/jlcr.3526

Surface charge and particle size determine the metabolic fate of dendritic polyglycerols

Pant, K.; Pufe, J.; Zarschler, K.; Bergmann, R.; Steinbach, J.; et al. (9 authors)

A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform

Albert, S.; Arndt, C.; Feldmann, A.; Bergmann, R.; Bachmann, D.; et al. (18 authors)

A novel tumor pretargeting system based on complementary L-configured oligonucleotides

Schubert, M.; Bergmann, R.; Förster, C.; Sihver, W.; Vonhoff, S.; et al. (12 authors)

X-ray Structures of Succinimidyl Halobenzoates

Mamat, C.; Weiss, D.-H.; Köckerling, M.

Zwitterionic Modification of Ultra-Small Iron Oxide Nanoparticles for Reduced Protein Corona Formation

Pombo-Garcia, K.; Rühl, C.; Lam, R.; Ang, C.-S.; Scammells, P. J.; et al. (10 authors)

Do spiroindolines have the potential to replace vesamicol as lead compound for the development of radioligands targeting the vesicular acetylcholine transporter?

Lindemann, M.; Deuther-Conrad, W.; Moldovan, R.; Sekhar, K. V. G. C.; Brust, P.; et al. (6 authors)

Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats

Bergmann, R.; Kubeil, M.; Zarschler, K.; Chhabra, S.; Tajhya, R. B.; et al. (10 authors)

In vivo examination of an injectable hydrogel system crosslinked by peptide-oligosaccharide interaction in immunocompetent nude mice

Tondera, C.; Wieduwild, R.; Röder, E.; Werner, C.; Zhang, Y.; et al. (6 authors)

Development of highly affine and selective fluorinated cannabinoid receptor type 2 ligands

Moldovan, R.-P.; Hausmann, K.; Deuther-Conrad, W.; Brust, P.

Development of Fluorinated Non-Peptidic Ghrelin Receptor Ligands for Potential Use in Molecular Imaging

Moldovan, R.-P.; Els-Heindl, S.; Worm, D. J.; Kniess, T.; Kluge, M.; et al. (9 authors)

PET Imaging of α7 Nicotinic Acetylcholine Receptors: A comparative study of [18F]ASEM and [18F]DBT-10 in non-human primates, and further evaluation of [18F]ASEM in humans

Hillmer, A. T.; Li, S.; Zheng, M.-Q.; Scheunemann, M.; Lin, S.-F.; et al. (17 authors)

The spatial coefficient of variation in arterial spin labeling cerebral blood flow images

Mutsaerts, H. J.; Petr, J.; Václavů, L.; van Dalen, J. W.; Robertson, A. D.; et al. (10 authors)

Retargeting of T lymphocytes to PSCA- or PSMA positive prostate cancer cells using the novel modular chimeric antigen receptor platform technology “UniCAR”

Feldmann, A.; Arndt, C.; Bergmann, R.; Loff, S.; Cartellieri, M.; et al. (20 authors)

Suppressed Fat Appetite after Roux-en-Y Gastric Bypass Surgery Associates with Reduced Brain µ-opioid Receptor Availability in Diet-Induced Obese Male Rats

Hankir, M.; Patt, M.; Patt, J.; Becker, G.; Rullmann, M.; et al. (14 authors)

Synthesis and in vitro evaluation of new fluorinated quinoline derivatives with high affinity for PDE5: Towards the development of new PET neuroimaging probes

Liu, J.; Maisonial-Besset, A.; Wenzel, B.; Canitrot, D.; Baufond, A.; et al. (8 authors)

The Why and How of Amino Acid Analytics in Cancer Diagnostics and Therapy

Manig, F.; Kuhne, K.; von Neubeck, C.; Schwarzenbolz, U.; Yu, Z.; et al. (8 authors)

Gender Differences in Neural Networks for Color Processing in Mice: A PET/MR Study

Njemanze, P. C.; Kranz, M.; Amend, M.; Wehrl, H.; Brust, P.

Dissociation between brown adipose tissue 18F-FDG uptake and thermogenesis in uncoupling protein deficient mice

Hankir, M. K.; Kranz, M.; Keipert, S.; Andreasen, S.; Kern, M.; et al. (11 authors)

Substrate-dependence of competitive nucleotide pyrophosphatase / phosphodiesterase1 (NPP1)

Lee, S.-Y.; Sarkar, S.; Bhattarai, S.; Namasivayam, V.; de Jonghe, S.; et al. (9 authors)

Predictive Value of Asphericity in Pretherapeutic [111In]DTPA-Octreotide SPECT/CT for Response to Peptide Receptor Radionuclide Therapy with [177Lu]DOTATATE

Wetz, C.; Apostolova, I.; Steffen, I. G.; Hofheinz, F.; Furth, C.; et al. (10 authors)

Human endothelial cell models in biomaterial research

Hauser, S.; Jung, F.; Pietzsch, J.

Synthesis and Preliminary Biological Evaluation of Indol-3-yl-oxoacetamides as Potent Cannabinoid Receptor Type 2 Ligands

Moldovan, R.-P.; Deuther-Conrad, W.; Horti, A. G.; Brust, P.

Radiolabelled polymeric materials for imaging and treatment of cancer: Quo Vadis?

Pant, K.; Sedláček, O.; Nadar, R. A.; Hrubý, M.; Stephan, H.

Hydrous 18F-fluoroethylation – leaving off the azeotropic drying

Kniess, T.; Laube, M.; Steinbach, J.

Adhesion- and stress-related adaptation of glioma radiochemoresistance is circumvented by β1 integrin/JNK co-targeting

Vehlow, A.; Klapproth, E.; Storch, K.; Dickreuter, E.; Seifert, M.; et al. (9 authors)

Cryogel-Supported Stem Cell Factory for Customized Sustained Release of Bispecific Antibodies for Cancer Immunotherapy

Aliperta, R.; Welzel, P. B.; Bergmann, R.; Freudenberg, R.; Berndt, N.; et al. (17 authors)

Gastric Bypass Surgery Recruits a Gut – Striatal Dopamine Pathway to Reduce Fat Appetite in Obese Rats

Hankir, M. K.; Seyfried, F.; Hintschich, C. A.; Diep, T. A.; Kleberg, K.; et al. (17 authors)

Insights into binding of S100 proteins to scavenger receptors: class B scavenger receptor CD36 binds S100A12 with high affinity

Tondera, C.; Laube, M.; Pietzsch, J.

A fluorescence anisotropy-based assay for determining the activity of tissue transglutaminase

Hauser, C.; Wodtke, R.; Löser, R.; Pietsch, M.

Radiosynthesis and biological evaluation of the new PDE10A radioligand [18F]AQ28A

Wagner, S.; Teodoro, R.; Deuther-Conrad, W.; Kranz, M.; Scheunemann, M.; et al. (11 authors)

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)1, 36-48
    Online First (2016) DOI: 10.1002/jlcr.3471

2016

Radiomics-based differentiation of lung disease models generated by polluted air based on X-ray computed tomography data

Szigeti, K.; Szabó, T.; Korom, C.; Ilona, C.; Horváth, I.; et al. (12 authors)

Generation of high-avidity, WT1-reactive CD8+ cytotoxic T cell clones with anti-leukemic activity by streptamer technology

Tunger, A.; Wehner, R.; von Bonin, M.; Kühn, D.; Heidenreich, F.; et al. (20 authors)

Targeting of β1 integrins impairs DNA repair for radiosensitization of head and neck cancer cells

Dickreuter, E.; Eke, I.; Krause, M.; Borgmann, K.; van Vugt, M. A.; et al. (6 authors)

New insights into the pretargeting approach to image and treat tumours

Patra, M.; Zarschler, K.; Pietzsch, H.-J.; Stephan, H.; Gasser, G.

Targetting microglia activation in schizophrenia by minocycline treatment

Mattei, D.; Ivanov, A.; Ferrai, G.; Jordan, P.; Guneykaya, D.; et al. (16 authors)

  • European Neuropsychopharmacology 26(2016), 134

Melanoma targeting with [99mTc(N)(PNP3)]-labeled α-melanocyte stimulating hormone peptide analogs: Effects of cyclization on the radiopharmaceutical properties

Carta, D.; Salvarese, N.; Morellato, N.; Gao, F.; Sihver, W.; et al. (12 authors)

Development of a F-18-labeled Diaryl-Substituted Dihydropyrrolo[3,2,1-hi]indole as Potential Probe for Functional Imaging of Cyclooxygenase-2 with PET

Gassner, C.; Neuber, C.; Laube, M.; Bergmann, R.; Kniess, T.; et al. (6 authors)

Moments-based ultrasound visual servoing: from mono to multi-plane approach

Nadeau, C.; Krupa, A.; Petr, J.; Barillot, C.

The asphericity of the metabolic tumour volume in NSCLC: correlation with histopathology and molecular markers

Apostolova, I.; Ego, K.; Steffen, I. G.; Buchert, R.; Wertzel, H.; et al. (14 authors)

Gelatin-based hydrogel degradation and tissue interaction in vivo: insights from multimodal preclinical imaging in immunocompetent nude mice

Tondera, C.; Ullm, S.; Krüger-Genge, A.; Jung, F.; Neffe, A. T.; et al. (10 authors)

Evaluation of the enantiomer specific biokinetics and radiation doses of [18-F]-fluspidine – a new tracer in clinical translation for imaging of σ1 receptors

Kranz, M.; Sattler, B.; Wüst, N.; Deuther-Conrad, W.; Patt, M.; et al. (13 authors)

Synthesis and evaluation of a 18F-labeled 4-phenylpiperidine-4-carbonitrile radioligand for σ1 receptor imaging

Ye, J.; Wang, X.; Deuther-Conrad, W.; Zhang, J.; Li, J.; et al. (10 authors)

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals (2016), 332-339
    DOI: 10.1002/jlcr.3408

Comparative evaluation of SUV, tumor-to-blood standard uptake ratio (SUR), and dual time point measurements for assessment of the metabolic uptake rate in FDG PET

Hofheinz, F.; van den Hoff, J.; Steffen, I. G.; Lougovski, A.; Ego, K.; et al. (7 authors)

Putaminal dopamine turnover in de novo Parkinson disease predicts later motor complications

Loehle, M.; Mende, J.; Wolz, M.; Beuthien-Baumann, B.; Oehme, L.; et al. (9 authors)

Switching CAR T cells on and off: A novel modular platform for retargeting of T cells to AML blasts

Cartellieri, M.; Feldmann, A.; Koristka, S.; Arndt, C.; Loff, S.; et al. (10 authors)

Zwitterionic polymer-coated ultrasmall superparamagnetic iron oxide nanoparticles with low protein interaction and high biocompatibility

Pombo-García, K.; Weiss, S.; Zarschler, K.; Ang, C.-S.; Hübner, R.; et al. (12 authors)

Tos-Nos-Mos: Synthesis of different aryl sulfonate precursors for the radiosynthesis of the alpha7 nicotinic acetylcholine receptor radioligand [18F]NS14490

Rötering, S.; Scheunemann, M.; Günther, R.; Löser, R.; Hiller, A.; et al. (9 authors)

Extracellular S100A4 affects endothelial cell integrity and stimulates transmigratory behavior of human A375 melanoma cells

Herwig, N.; Belter, B.; Pietzsch, J.

Radiation dosimetry of the α4β2 nicotinic receptor ligand (+)-[18F]Flubatine, comparing preclinical PET/MRI and PET/CT to first-in-human PET/CT results

Kranz, M.; Sattler, B.; Tiepolt, S.; Wilke, S.; Deuther-Conrad, W.; et al. (15 authors)

Polyglycerol-Based Copper Chelators for the Transport and Release of Copper Ions in Biological Environments

Albrecht, R.; Fehse, S.; Pant, K.; Nowag, S.; Stephan, H.; et al. (7 authors)

Direct and Auger electron-induced, single- and double-strand breaks on plasmid DNA caused by 99mTc-labeled pyrene derivatives and the effect of bonding distance

Reissig, F.; Mamat, C.; Steinbach, J.; Pietzsch, H.-J.; Freudenberg, R.; et al. (7 authors)

Synthesis and kinetic characterisation of water-soluble fluorogenic acyl donors for transglutaminase 2

Wodtke, R.; Schramm, G.; Pietzsch, J.; Pietsch, M.; Löser, R.

Novel radioligands for cyclic nucleotide phosphodiesterase imaging with positron emission tomography: An update on developments since 2012

Schröder, S.; Wenzel, B.; Deuther-Conrad, W.; Scheunemann, M.; Brust, P.

Multimodal Somatostatin Receptor Theranostics Using [64Cu]Cu-/[177Lu]Lu-DOTA-(Tyr3)octreotate and AN-238 in a Mouse Pheochromocytoma Model.

Ullrich, M.; Bergmann, R.; Peitzsch, M.; Zenker, E.; Cartellieri, M.; et al. (13 authors)

Varying Chirality Across Nicotinic Acetylcholine Receptor Subtypes: Selective Binding of Quinuclidine Triazole Compounds

Sarasamkan, J.; Scheunemann, M.; Apaijai, N.; Palee, S.; Parichatikanond, W.; et al. (12 authors)

Comparison of in silico, electrochemical, in vitro and in vivo metabolism of a homologous series of (radio)fluorinated sigma1 receptor ligands designed for positron emission tomography

Wiese, C.; Große Maestrup, E.; Galla, F.; Schepmann, D.; Hiller, A.; et al. (13 authors)

Beta-Amyloid-PET-Bildgebung des Gehirns - DGN-Handlungsempfehlung

Barthel, H.; Meyer, P. T.; Drzezga, A.; Bartenstein, P.; Boecker, H.; et al. (17 authors)

Rational Structure-Based Rescaffolding Approach to de Novo Design of Interleukin 10 (IL-10) Receptor-1 Mimetics

Ruiz-Gómez, G.; Hawkins, J. C.; Philipp, J.; Künze, G.; Wodtke, R.; et al. (8 authors)

Development of antioxidant COX-2 inhibitors as radioprotective agents for radiation therapy – a hypothesis-driven review

Laube, M.; Kniess, T.; Pietzsch, J.

99mTc-Cyclopentadienyl Tricarbonyl Chelate-Labeled Compounds as Selective Sigma‑2 Receptor Ligands for Tumor Imaging

Li, D.; Chen, Y.; Wang, X.; Deuther-Conrad, W.; Chen, X.; et al. (11 authors)

LC-MS supported Studies on the in vitro Metabolism of both Enantiomers of Flubatine and the in vivo Metabolism of (+)-[18F]Flubatine – a Positron Emission Tomography Radioligand for Imaging α4β2-Nicotinic Acetylcholine Receptors

Ludwig, F.-A.; Smits, R.; Fischer, S.; Donat, C. K.; Hoepping, A.; et al. (7 authors)

Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice

Weiner, J.; Kranz, M.; Klöting, N.; Kunath, A.; Steinhoff, K.; et al. (20 authors)

Changes in Binding of [123I]CLINDE, a High-Affinity Translocator Protein 18 kDa (TSPO) Selective Radioligand in a Rat Model of Traumatic Brain Injury

Donat, C. K.; Gaber, K.; Meixensberger, J.; Brust, P.; Pinborg, L. H.; et al. (7 authors)

Development of a High-Affinity PET Radioligand for Imaging Cannabinoid Subtype 2 Receptor

Moldovan, R.-P.; Teodoro, R.; Deuther-Conrad, W.; Kranz, M.; Wang, Y.; et al. (13 authors)

Ultrasmall inorganic nanoparticles: state-of-the-art and perspectives for biomedical applications

Zarschler, K.; Rocks, L.; Licciardello, N.; Boselli, L.; Polo, E.; et al. (9 authors)

An investigation of the relation between tumor-to-liver ratio (TLR) and tumor-to-blood standard uptake ratio (SUR) in oncological FDG PET.

Hofheinz, F.; Bütof, R.; Apostolova, I.; Zöphel, K.; Steffen, I. G.; et al. (9 authors)

Early and late effects of radiochemotherapy on cerebral blood flow in glioblastoma patients measured with non-invasive perfusion MRI

Petr, J.; Platzek, I.; Seidlitz, A.; Mutsaerts, H. J. M. M.; Hofheinz, F.; et al. (10 authors)

5-Chloro-1-phenylpentan-1-one

Bechmann, N.; Kniess, T.; Pietzsch, J.; König, J.; Köckerling, M.

Nuclear and optical dual-labelled imaging agents: Design and challenges

Singh, G.; Gott, M.; Pietzsch, H.-J.; Stephan, H.

  • Open Access Logo Nuklearmedizin 55(2016)2, 41-50

Development of a new radiofluorinated quinoline analog for PET imaging of phosphodiesterase 5 (PDE5) in brain.

Liu, J.; Wenzel, B.; Dukic-Stefanovic, S.; Teodoro, R.; Ludwig, F.-A.; et al. (11 authors)

Synthesis, dynamic NMR characterization and XRD studies of novel N,N’-substituted piperazines for bioorthogonal labeling

Mamat, C.; Pretze, M.; Gott, M.; Köckerling, M.

The Radiochemical and radiopharmaceutical applications of radium

Gott, M.; Steinbach, J.; Mamat, C.

177Lu-labelled macrocyclic bisphosphonates for targeting bone metastasis in cancer treatment

Bergmann, R.; Meckel, M.; Kubicek, V.; Pietzsch, J.; Steinbach, J.; et al. (7 authors)

Radiopharmacological characterization of 64Cu-labeled α-MSH analogs for potential use in imaging of malignant melanoma

Gao, F.; Sihver, W.; Jurischka, C.; Bergmann, R.; Haase-Kohn, C.; et al. (12 authors)

Characterization of the microbunch time structure of proton pencil beams at a clinical treatment facility

Petzoldt, J.; Römer, K. E.; Enghardt, W.; Fiedler, F.; Golnik, C.; et al. (12 authors)

PET imaging evaluation of [18F]DBT-10, a novel radioligand specific to α7 nicotinic acetylcholine receptors, in nonhuman primates

Hillmer, A. T.; Zheng, M.-Q.; Li, S.; Scheunemann, M.; Lin, S.-F.; et al. (13 authors)

  • European Journal of Nuclear Medicine and Molecular Imaging 43(2016)3, 537-547
    Online First (2015) DOI: 10.1007/s00259-015-3209-0

A novel thermoregulatory role for PDE10A in mouse and human adipocytes

Hankir, M.; Kranz, M.; Gnad, T.; Wagner, S.; Deuther-Conrad, W.; et al. (16 authors)

Interaction of extracellular S100A4 with RAGE prompts prometastatic activation of A375 melanoma cells

Herwig, N.; Belter, B.; Wolf, S.; Haase-Kohn, C.; Pietzsch, J.

Development of highly potent phosphodiesterase 10A (PDE10A) inhibitors: Synthesis and in vitro evaluation of 1,8-dipyridyl- and 1-pyridinol-substituted imidazo[1,5-a]quinoxalines

Wagner, S.; Scheunemann, M.; Dipper, K.; Egerland, U.; Hoefgen, N.; et al. (7 authors)

On the development of a novel non-peptidic 18F-labeled radiotracer for in vivo imaging of oxytocin receptors with positron emission tomography

Wenzel, B.; Mollitor, J.; Deuther-Conrad, W.; Kranz, M.; Dukic-Stefanovic, S.; et al. (13 authors)

2015

Positron emission tomography 2013 in Germany: Results of the query and current status

Kotzerke, J.; Oehme, L.; Grosse, J.; Hellwig, D.; Bartenstein, P.; et al. (23 authors)

Protective effects of 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors on oxidative modification of human low density lipoproteins in vitro

Pietzsch, J.; Laube, M.; Bechmann, N.; Pietzsch, F.-J.; Kniess, T.

  • Clinical Hemorheology and Microcirculation 61(2015)4, 615-632
    DOI: 10.3233/CH-141923
    ISSN: 1386-0291

Improved Killing of AML Blasts By Dual-Targeting of CD123 and CD33 Via Unitarg a Novel Antibody-Based Modular T Cell Retargeting System

Arndt, C.; Feldmann, A.; Koristka, S.; Cartellieri, M.; von Bonin, M.; et al. (9 authors)

  • BLOOD 126(2015), 2565

Increased evidence for the prognostic value of primary tumor asphericity in pretherapeutic FDG PET for risk stratification in patients with head and neck cancer.

Hofheinz, F.; Lougovski, A.; Zöphel, K.; Hentschel, M.; Steffen, I. G.; et al. (12 authors)

Controlled immobilization of His-tagged proteins for protein-ligand interaction experiments using Ni2+-NTA layer on glass surfaces

Cherkouk, C.; Rebohle, L.; Lenk, J.; Keller, A.; Ou, X.; et al. (10 authors)

Probleme der SUV-Quantifizierung in der Positronenemissionstomografie und mögliche Lösungswege/Problems of SUV Quantification in Positron Emission Tomography and Possible Solutions

van den Hoff, J.; Hofheinz, F.

Cyclam Derivatives with a Bis(phosphinate) or a Phosphinato−Phosphonate Pendant Arm: Ligands for Fast and Efficient Copper(II) Complexation for Nuclear Medical Applications

David, T.; Kubićek, V.; Gutten, O.; Lubal, P.; Kotek, J.; et al. (8 authors)

Influence of irradiation on release of endothelial microparticles (EMP) in vitro

Neuber, C.; Pufe, J.; Pietzsch, J.

  • Clinical Hemorheology and Microcirculation 61(2015)2, 291-299
    DOI: 10.3233/CH-151987
    ISSN: 1386-0291

Spatial distribution of FMISO in head and neck squamous cell carcinomas during radio-chemotherapy and its correlation to pattern of failure

Zschaeck, S.; Haase, R.; Abolmaali, N.; Perrin, R.; Stützer, K.; et al. (14 authors)

Prognostic Value of Pretherapeutic Tumor-to-Blood Standardized Uptake Ratio in Patients with Esophageal Carcinoma

Bütof, R.; Hofheinz, F.; Zöphel, K.; Stadelmann, T.; Schmollack, J.; et al. (10 authors)

Correction of quantification errors in pelvic and spinal lesions caused by ignoring higher photon attenuation of bone in [18F]NaF PET/MR

Schramm, G.; Maus, J.; Hofheinz, F.; Petr, J.; Lougovski, A.; et al. (9 authors)

Evaluation of in vivo quantification accuracy of the Ingenuity-TF PET/MR

Maus, J.; Schramm, G.; Hofheinz, F.; Oehme, L.; Lougovski, A.; et al. (11 authors)

Bispecific antibody releasing-mesenchymal stromal cell machinery for retargeting T cells towards acute myeloid leukemia blasts

Aliperta, R.; Cartellieri, M.; Feldmann, A.; Arndt, C.; Koristka, S.; et al. (12 authors)

18F-Labeled 1,4-Dioxa-8-azaspiro[4.5]decane Derivative: Synthesis and Biological Evaluation of a σ1 Receptor Radioligand with Low Lipophilicity as Potent Tumor Imaging Agent

Xie, F.; Bergmann, R.; Kniess, T.; Deuther-Conrad, W.; Mamat, C.; et al. (11 authors)

Targeting lysyl oxidase for molecular imaging in breast cancer

Wuest, M.; Kuchar, M.; Sharma, S. K.; Richter, S.; Hamann, I.; et al. (10 authors)

18F-FDG PET/MRI for therapy response assessment in sarcoma: Comparison of PET and MR imaging results

Schuler, M. K.; Platzek, I.; Beuthien-Baumann, B.; Fenchel, M.; Ehninger, G. E.; et al. (6 authors)

2-[18F]Fluoroethyl tosylate - a versatile tool for building 18F-based radiotracers for positron emission tomography

Knieß, T.; Laube, M.; Brust, P.; Steinbach, J.

Repeatability of tumor SUV quantification: the role of variable blood SUV

van den Hoff, J.; Hofheinz, F.

Novel (pyrazolyl)benzenesulfonamides with a nitric oxide-releasing moiety as selective cyclooxygenase-2 inhibitors

Bechmann, N.; Kniess, T.; Köckerling, M.; Pigorsch, A.; Steinbach, J.; et al. (6 authors)

Rational design of dual peptides targeting ghrelin and Y2 receptors to regulate food intake and body weight

Kilian, T. M.; Klöting, N.; Bergmann, R.; Els-Heindl, S.; Babilon, S.; et al. (9 authors)

  • Journal of Medicinal Chemistry 58(2015), 4180-4193
    DOI: 10.1021/jm501702q
    ISSN: 0022-2623

On the relation between Kaiser-Bessel blob and tube of response based modelling of the system matrix in iterative PET image reconstruction

Lougovski, A.; Hofheinz, F.; Maus, J.; Schramm, G.; van den Hoff, J.

Methods to increase the metabolic stability of 18F-radiotracers

Kuchar, M.; Mamat, C.

In vivo Demonstration of an Active Tumor Pretargeting Approach with Peptide Nucleic Acid Bioconjugates as Complementary System

Leonidova, A.; Foerster, C.; Zarschler, K.; Schubert, M.; Pietzsch, H.-J.; et al. (10 authors)

Synthesis and First Evaluation of [18F]Fluorocyano- and [18F]Fluoronitroquinoxalinedione as Putative AMPA Receptor Antagonists

Olma, S.; Ermert, J.; Sihver, W.; Coenen, H.-H.

Biodistribution, cellular localization, and in vivo tolerability of S-35-labeled antiinflammatory dendritic polyglycerol sulfate amine

Holzhausen, C.; Groger, D.; Mundhenk, L.; Donat, C. K.; Schnorr, J.; et al. (7 authors)

Active Site Mapping of Human Cathepsin F with Dipeptide Nitrile Inhibitors

Schmitz, J.; Furtmann, N.; Ponert, M.; Frizler, M.; Löser, R.; et al. (8 authors)

Cysteine cathepsins: their role in tumor progression and recent trends in the development of imaging probes

Löser, R.; Pietzsch, J.

Copper(II) cyclam complexes with N-propionic acid pendant arms

Kubeil, M.; Zarschler, K.; Pietzsch, J.; Kraus, W.; Comba, P.; et al. (6 authors)

Novel indole-based sigma-2 receptor ligands: synthesis, structure–affinity relationship and antiproliferative activity

Xie, F.; Kniess, T.; Neuber, C.; Deuther-Conrad, W.; Mamat, C.; et al. (12 authors)

First-in-human PET quantification study of cerebral α4β2* nicotinic acetylcholine receptors using the novel specific radioligand (−)-[18F]Flubatine

Sabri, O.; Becker, G.-A.; Meyer, P. M.; Hesse, S.; Wilke, S.; et al. (21 authors)

Combined PET/MR: The Real Work Has Just Started. Summary Report of the Third International Workshop on PET/MR Imaging; February 17-21, 2014, Tubingen, Germany

Bailey, D. L.; Antoch, G.; Bartenstein, P.; Barthel, H.; Beer, A. J.; et al. (27 authors)

The association of tumor-to-background ratios and SUVmax deviations related to point spread function and time-of-flight F18-FDG-PET/CT reconstruction in colorectal liver metastases

Rogasch, J. M. M.; Steffen, I. G.; Hofheinz, F.; Großer, O. S.; Furth, C.; et al. (10 authors)

Synthesis and Molecular Structure of 2-(Diphenylphosphano) phenyl Benzoate Borane Adduct

Mamat, C.; Köckerling, M.

DAP12-Based Activating Chimeric Antigen Receptor for NK Cell Tumor Immunotherapy

Toepfer, K.; Cartellieri, M.; Michen, S.; Wiedemuth, R.; Mueller, N.; et al. (10 authors)

A promising PET tracer for imaging of α7 nicotinic acetylcholine receptors in the brain: Design, synthesis, and in vivo evaluation of a dibenzothiophene-based radioligand

Teodoro, R.; Scheunemann, M.; Deuther-Conrad, W.; Wenzel, B.; Colombo, S.; et al. (16 authors)

CuII-selective bispidine–dye conjugates

Bronx, D.; Comba, P.; Herten, D.-P.; Kimmle, E.; Morgen, M.; et al. (10 authors)

Improving external beam radiotherapy by combination with internal irradiation.

Dietrich, A.; Koi, L.; Zöphel, K.; Sihver, W.; Kotzerke, J.; et al. (7 authors)

Synthesis and Biodistribution Studies of 3H- and 64Cu-labeled Dendritic Polyglycerol and Dendritic Polyglycerol Sulfate

Pant, K.; Gröger, D.; Bergmann, R.; Pietzsch, J.; Steinbach, J.; et al. (13 authors)

Synthesis, 18F-radiolabelling and biological characterization of novel fluoroalkylated triazine derivatives for in vivo imaging of phosphodiesterase 2A in brain via positron emission tomography

Schröder, S.; Wenzel, B.; Deuther-Conrad, W.; Teodoro, R.; Egerland, U.; et al. (10 authors)

Development of indazolylpyrimidine derivatives as high-affine EphB4 receptor ligands and potential PET-radiotracers

Ebert, K.; Wiemer, J.; Caballero, J.; Köckerling, M.; Steinbach, J.; et al. (7 authors)

Reduced pulmonary blood flow in regions of injury 2 hours after acid aspiration in rats

Richter, T.; Bergmann, R.; Musch, G.; Pietzsch, G.; Koch, T.

Accuracy of parenchymal cerebral blood flow measurements using pseudo-continuous arterial spin labeling in healthy volunteers

Ambarki, K.; Wåhlin, A.; Zarrinkoob, L.; Wirestam, R.; Petr, J.; et al. (7 authors)

Tregs activated by bispecific antibodies: Killers or suppressors?

Koristka, S.; Cartellieri, M.; Arndt, C.; Feldmann, A.; Seliger, B.; et al. (7 authors)

Optical imaging of COX-2: Studies on an autofluorescent 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitor.

Tondera, C.; Ullm, S.; Laube, M.; Meister, S.; Neuber, C.; et al. (8 authors)

Theranostic mercury: 197(m)Hg with high specific activity for imaging and therapy

Walther, M.; Preusche, S.; Bartel, S.; Wunderlich, G.; Freudenberg, R.; et al. (7 authors)

New systematically modified vesamicol analogs and their affinity and selectivity for the vesicular acetylcholine transporter – A critical examination of the lead structure.

Barthel, C.; Sorger, D.; Deuther-Conrad, W.; Scheunemann, M.; Schweiger, S.; et al. (12 authors)

Cyclopeptides containing the DEKS motif as conformationally restricted collagen telopeptide analogues: synthesis and conformational analysis

Wodtke, R.; Ruiz-Gómez, G.; Kuchar, M.; Pisabarro, M. T.; Novotná, P.; et al. (9 authors)

Speciation of uranium in compartments of living cells

Geipel, G.; Viehweger, K.

Bifunctional Cyclam-Based Ligands with Phosphorus Acid Pendant Moieties for Radiocopper Separation – Thermodynamic and Kinetic Studies

Paúrová, M.; Havlíčková, J.; Pospíšilová, A.; Vetrík, M.; Císařová, I.; et al. (10 authors)

Diaryl-substituted (dihydro)pyrrolo[3,2,1-hi]indoles, a class of potent COX-2 inhibitors with tricyclic core structure

Laube, M.; Gassner, C.; Sharma, S. K.; Günther, R.; Pigorsch, A.; et al. (10 authors)

Polyoxometalates - potent and selective ecto-nucleotidase inhibitors

Lee, S.-Y.; Fiene, A.; Li, W.; Hank, T.; Brylev, K.; et al. (14 authors)

A high-yield automated radiosynthesis of the alpha-7 nicotinic receptor radioligand [18F]NS10743

Teodoro, R.; Wenzel, B.; Oh-Nishi, A.; Fischer, S.; Peters, D.; et al. (8 authors)

Effects of pulmonary acid aspiration on the regional pulmonary blood flow within the first hour after injury: an observational study in rats

Richter, T.; Bergmann, R.; Pietzsch, J.; Mueller, M. P.; Koch, T.

  • Clinical Hemorheology and Microcirculation 60(2015), 253-262
    Online First (2014) DOI: 10.3233/CH-141867

Convenient recycling and reuse of bombarded [18O]H2O for the production and the application of [18F]F‒

Rötering, S.; Franke, K.; Zessin, J.; Brust, P.; Füchtner, F.; et al. (7 authors)

Evaluation of Novel Fluorescence Probes for Conjugation Purposes Using the Traceless Staudinger Ligation

Wodtke, R.; König, J.; Pigorsch, A.; Köckerling, M.; Mamat, C.

2014

Quantitative assessment of the asphericity of pretherapeutic FDG uptake as an independent predictor of outcome in NSCLC.

Apostolova, I.; Rogasch, J.; Buchert, R.; Wertzel, H.; Achenbach, H. J.; et al. (13 authors)

The influence of different signal-to-background ratios on spatial resolution and F18-FDG-PET quantification using point spread function and time-of-flight reconstruction

Rogasch, J. M. M.; Hofheinz, F.; Lougovski, A.; Furth, C.; Ruf, J.; et al. (11 authors)

Dual Role of B7 Costimulation in Obesity-Related Nonalcoholic Steatohepatitis and Metabolic Dysregulation

Chatzigeorgiou, A.; Chung, K.-J.; Garcia-Martin, R.; Alexaki, V.-I.; Klotzsche-Von Ameln, A.; et al. (22 authors)

FDG PET/MR for the Assessment of Lymph Node Involvement in Lymphoma: Initial Results and Role of Diffusion-Weighted MR

Platzek, I.; Beuthien-Baumann, B.; Ordemann, R.; Maus, J.; Schramm, G.; et al. (9 authors)

Preparation of 4-Halobenzoate Containing Phosphane Based Building Blocks for Labeling Reactions Using the Traceless Staudinger Ligation

Mamat, C.; Köckerling, M.

X-ray structure of 2-(diphenylphosphano)phenyl-4-(hydroxymethyl)benzoate

Mamat, C.; Flemming, A.; Köckerling, M.

Organotypical vascular model for characterization of radioprotective compounds: Studies on antioxidant 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors

Ullm, S.; Laube, M.; Bechmann, N.; Knieß, T.; Pietzsch, J.

  • Clinical Hemorheology and Microcirculation 58(2014), 281-295
    DOI: 10.3233/CH-141902

Internal Dose Assessment of (-)-18F-Flubatine, Comparing Animal Model Datasets of Mice and Piglets with First-in-Human Results

Sattler, B.; Kranz, M.; Starke, A.; Wilke, S.; Donat, C. K.; et al. (15 authors)

Redirection of CD4+ and CD8+ T lymphocytes via a novel antibody-based modular targeting system triggers efficient killing of PSCA+ prostate tumor cells

Arndt, C.; Feldmann, A.; Töpfer, K.; Koristka, S.; Cartellieri, M.; et al. (9 authors)

Synthesis and evaluation of a 18F-labeled spirocyclic piperidine derivative as promising σ1 receptor imaging agent

Chen, Y.-Y.; Wang, X.; Zhang, J.-M.; Deuther-Conrad, W.; Zhang, X.-J.; et al. (12 authors)

Novel Cyclopentadienyl Tricarbonyl 99mTc Complexes Containing 1‑Piperonylpiperazine Moiety: Potential Imaging Probes for Sigma‑1 Receptors

Wang, X.; Li, D.; Deuther-Conrad, W.; Lu, J.; Xie, Y.; et al. (11 authors)

Characterization of circulating microparticle-associated CD39 family ecto-nucleotidases in human plasma

Jiang, Z. G.; Wu, Y.; Csizmadia, E.; Feldbrügge, L.; Enjyoji, K.; et al. (12 authors)

The Ti7-Containing, Tetrahedral 36-Tungsto-4-Arsenate(III)[Ti6(TiO6)(AsW9O33)4]20-

Wang, K.-Y.; Bassil, B. S.; Lin, Z. G.; Haider, A.; Cao, J.; et al. (8 authors)

Bispidines for dual imaging

Stephan, H.; Walther, M.; Fähnemann, S.; Ceroni, P.; Molloy, J.; et al. (10 authors)

2,3-Diaryl-substituted indole based COX-2 inhibitors as leads for imaging tracer development

Laube, M.; Tondera, C.; Sharma, S. K.; Bechmann, N.; Pietzsch, F.-J.; et al. (10 authors)

In Vivo Fluorescence Imaging and Urinary Monoamines as Surrogate Biomarkers of Disease Progression in a Mouse Model of Pheochromocytoma

Ullrich, M.; Bergmann, R.; Peitzsch, M.; Cartellieri, M.; Quin, N.; et al. (12 authors)

Biocompatibility and inflammatory response in vitro and in vivo to gelatin-based biomaterials with tailorable elastic properties

Ullm, S.; Krüger, A.; Tondera, C.; Gebauer, T. P.; Neffe, A. T.; et al. (8 authors)

Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors

Gnad, T.; Scheibler, S.; von Kügelgen, I.; Scheele, C.; Kilic, A.; et al. (21 authors)

Asphericity of pretherapeutic tumour FDG uptake provides independent prognostic value in head-and-neck cancer

Apostolova, I.; Steffen, I. G.; Wedel, F.; Lougovski, A.; Marnitz, S.; et al. (10 authors)

Periacetabular bone metabolism following hip revision surgery. PET-based evaluation of allograft osteointegration.

Bernstein, P.; Beuthien-Baumann, B.; Kotzerke, J.; Hofheinz, F.; Zessin, J.; et al. (7 authors)

Zwitterionic-Coated "Stealth" Nanoparticles for Biomedical Applications: Recent Advances in Countering Biomolecular Corona Formation and Uptake by the Mononuclear Phagocyte System

Pombo Garcia, K.; Zarschler, K.; Barbaro, L.; Barreto, J. A.; O'Malley, W.; et al. (8 authors)

Evaluation of metabolism, plasma protein binding and other biological parameters after administration of (−)-[18 F]Flubatine in humans

Patt, M.; Becker, G. A.; Grossmann, U.; Habermann, B.; Schildan, A.; et al. (17 authors)

Assessment of the best N3− donors in preparation of [M(N)(PNP)]-based (M = 99mTc-; 188Re) target-specific radiopharmaceuticals: Comparison among succinic dihydrazide (SDH), N-methyl-S-methyl dithiocarbazate (HDTCZ) and PEGylated N-methyl-S-methyl dithiocarbazate (HO2C-PEG600-DTCZ)

Carta, D.; Jentschel, C.; Thieme, S.; Salvarese, N.; Morellato, N.; et al. (10 authors)

Imaging of α7 nicotinic acetylcholine receptors in brain and cerebral vasculature of juvenile pigs with [18F]NS14490

Rötering, S.; Deuther-Conrad, W.; Cumming, P.; Donat, C. K.; Scheunemann, M.; et al. (12 authors)

Bispidine dioxotetraaza macrocycles: a new class of bispidines for 64Cu PET imaging

Comba, P.; Kubeil, M.; Pietzsch, J.; Rudolf, H.; Stephan, H.; et al. (6 authors)

Radiofluorination and first radiopharmacological characterization of a SWLAY peptide-based ligand targeting EphA2

Pretze, M.; Mosch, B.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; et al. (6 authors)

  • Journal of Labelled Compounds and Radiopharmaceuticals 57(2014), 660-665
    DOI: 10.1002/jlcr.3237

Proinflammatory human 6-sulfo LacNAc-positive dendritic cells accumulate in intestinal acute graft-versus-host disease

Sommer, U.; Larsson, B.; Tuve, S.; Wehner, R.; Zimmermann, N.; et al. (18 authors)

Combined measurement of tumor perfusion and glucose metabolism for improved tumor characterization in advanced cervical carcinoma: A PET/CT pilot study using [15O]water and [18F]fluorodeoxyglucose

Apostolova, I.; Hofheinz, F.; Buchert, R.; Steffen, I. G.; Michel, R.; et al. (11 authors)

Effect of [18F]FMISO stratified dose-escalation on local control in FaDu hSCC in nude mice

Schütze, C.; Bergmann, R.; Brüchner, K.; Mosch, B.; Yaromira, A.; et al. (13 authors)

Potential of a Cetuximab-based radioimmunotherapy combined with external irradiation manifests in a 3-D cell assay

Ingargiola, M.; Runge, R.; Heldt, J.-M.; Freudenberg, R.; Steinbach, J.; et al. (10 authors)

  • International Journal of Cancer 135(2014), 968-980
    DOI: 10.1002/ijc.28735
    ISSN: 1097-0215

Evaluation and automatic correction of metal-implant-induced artifacts in MR-based attenuation correction in whole-body PET/MR imaging

Schramm, G.; Maus, J.; Hofheinz, F.; Petr, J.; Lougovski, A.; et al. (8 authors)

EGF receptor-targeting peptide conjugate incorporating a near-IR fluorescent dye and a novel 1,4,7-triazacyclononane-based 64Cu(II) chelator assembled via click chemistry

Viehweger, K.; Barbaro, L.; Pombo García, K.; Joshi, T.; Geipel, G.; et al. (9 authors)

Diagnostic nanoparticle targeting of the EGF-receptor in complex biological conditions using single-domain antibodies

Zarschler, K.; Prapainop, K.; Mahon, E.; Rocks, L.; Bramini, M.; et al. (8 authors)

Early increase of cannabinoid receptor density after experimental traumatic brain injury in the newborn piglet

Donat, C. K.; Fischer, F.; Walter, B.; Deuther-Conrad, W.; Brodhun, M.; et al. (7 authors)

  • Open Access Logo Acta Neurobiologiae Experimentalis 74(2014), 197-210
    ISSN: 0365-0820

Cytotoxic properties of radionuclide-conjugated Cetuximab without and in combination with external irradiation in head and neck cancer cells in vitro

Eke, I.; Ingargiola, M.; Förster, C.; Kunz-Schughart, L.; Baumann, M.; et al. (12 authors)

FDG PET/MR for lymph node staging in head and neck cancer

Platzek, I.; Beuthien-Baumann, B.; Schneider, M.; Gudziol, V.; Kitzler, H. H.; et al. (11 authors)

Distinctive In Vivo Kinetics of the New Sigma1 Receptor Ligands (R)-(+) and (S)-(-)- 18F-Fluspidine in Porcine Brain

Brust, P.; Deuther-Conrad, W.; Becker, G.; Patt, M.; Dont, C. K.; et al. (15 authors)

Correction of scan time dependence of standard uptake values in oncological PET

van den Hoff, J.; Lougovski, A.; Schramm, G.; Maus, J.; Oehme, L.; et al. (9 authors)

Combined PET/MR: Where Are We Now? Summary Report of the Second International Workshop on PET/MR Imaging April 8–12, 2013, Tubingen, Germany

Bailey, D. L.; Barthel, H.; Beuthien-Baumann, B.; Beyer, T.; Bisdas, S.; et al. (29 authors)

Metastatic potential of B16-F10 melanoma cells is enhanced by extracellular S100A4 derived from RAW264.7 macrophages

Haase-Kohn, C.; Wolf, S.; Herwig, N.; Mosch, B.; Pietzsch, J.

Simultaneous Targeting of Prostate Stem Cell Antigen and Prostate-Specific Membrane Antigen Improves the Killing of Prostate Cancer Cells Using a Novel Modular T Cell-Retargeting System

Arndt, C.; Feldmann, A.; Koristka, S.; Cartellieri, M.; Dimmel, M.; et al. (8 authors)

A novel ex vivo Isolation and Expansion Procedure for Chimeric Antigen Receptor Engrafted Human T Cells

Cartellieri, M.; Koristka, S.; Arndt, C.; Feldmann, A.; Stamova, S.; et al. (15 authors)

Characterization of a novel single-chain bispecific antibody for retargeting of T cells to tumor cells via the TCR co-receptor CD8

Michalk, I.; Feldmann, A.; Koristka, S.; Arndt, C.; Cartellieri, M.; et al. (8 authors)

Letter to the editor: Cytotoxic response of human regulatory 1 T cells upon T cell receptor-mediated activation – a 2 matter of purity

Koristka, S.; Cartellieri, M.; Arndt, C.; Feldmann, A.; Töpfer, K.; et al. (9 authors)

Visualizing inflammation activity in rheumatoid arthritis with Tc-99 m Anti-CD4-mAb fragment scintigraphy

Steinhoff, K.; Pierer, M.; Siegert, J.; Pigla, U.; Laub, R.; et al. (15 authors)

Influence of different chelators on the radiochemical properties of a 68-Gallium labelled bombesin analogue.

Asti, M.; Iori, M.; Capponi, P. C.; Atti, G.; Rubagotti, S.; et al. (11 authors)

Radiolabeled anti-EGFR-antibody improves local tumor control after external beam radiotherapy and offers theragnostic potential

Koi, L.; Bergmann, R.; Brüchner, K.; Pietzsch, J.; Pietzsch, H.-J.; et al. (9 authors)

Establishment of two complementary in vitro assays for radiocopper complexes achieving reliable and comparable evaluation of in vivo stability

Zarschler, K.; Kubeil, M.; Stephan, H.

TCR/CD3 activation and co-stimulation combined in one T cell retargeting system improve anti-tumor immunity

Cartellieri, M.; Arndt, C.; Feldmann, A.; von Bonin, M.; Ewen, E.-M.; et al. (14 authors)

Evaluation of PET quantification accuracy in vivo - Comparison of measured FDG concentration in the bladder with urine samples / In-vivo-Evaluation der Quantifizierungsgenauigkeit der PET - Vergleich der gemessenen FDG-Konzentration in der Blase mit Urinproben

Maus, J.; Hofheinz, F.; Schramm, G.; Oehme, L.; Beuthien-Baumann, B.; et al. (10 authors)

Costimulation improves the killing capability of T cells redirected to tumor cells expressing low levels of CD33: Description of a novel modular targeting system

Arndt, C.; Feldmann, A.; von Bonin, M.; Cartellieri, M.; Ewen, E.-M.; et al. (14 authors)

Asymmetric Synthesis of Spirocyclic 2-Benzopyrans for Positron Emission Tomography of σ1 Receptors in the Brain

Holl, K.; Schepmann, D.; Fischer, S.; Ludwig, F. A.; Hiller, A.; et al. (9 authors)

A volume of intersection approach for on-the-fly system matrix calculation in 3D PET image reconstruction

Lougovski, A.; Hofheinz, F.; Langner, J.; Schramm, G.; Will, E.; et al. (6 authors)

Synthesis and biological evaluation of both enantiomers of [18F]flubatine, promising radiotracers with fas kinetics for the imaging of α4β2-nicotinic acetylcholine receptors

Smits, R.; Fischer, S.; Hiller, A.; Deuther-Conrad, W.; Wenzel, B.; et al. (11 authors)

Development of 18F-labeled radiotracers for neuroreceptor imaging with positron emission tomography

Brust, P.; van den Hoff, J.; Steinbach, J.

Radiolabeled cetuximab conjugates for EGFR targeted cancer diagnostics and therapy

Sihver, W.; Pietzsch, J.; Krause, M.; Baumann, M.; Steinbach, J.; et al. (6 authors)

Performance Evaluation of Stationary and Semi-Stationary Acquisition with a Non-Stationary Small Animal Multi-Pinhole SPECT System

Lange, C.; Apostolova, I.; Lukas, M.; Huang, K. P.; Hofheinz, F.; et al. (8 authors)

Hydroxyalkylation with Cyclic Sulfates: Synthesis of Carbazole Derived CB2 Ligands with Increased Polarity

Lueg, C.; Galla, F.; Frehland, B.; Schepmann, D.; Daniliuc, C. G.; et al. (8 authors)

Automation of the radiosynthesis and purification procedures for [18F]Fluspidine preparation, a new radiotracer for clinical investigations in PET imaging of σ1 receptors in brain.

Maisonial-Besset, A.; Funke, U.; Wenzel, B.; Fischer, S.; Holl, K.; et al. (8 authors)

Molecular Imaging of σ1 Receptors In Vivo: Current Status and Perspectives

Brust, P.; Deuther-Conrad, W.; Lehmkuhl, K.; Jia, H.; Wünsch, B.

Modeling Magnetization Transfer Effects of Q2TIPS Bolus Saturation in Multi-TI Pulsed Arterial Spin Labeling

Petr, J.; Schramm, G.; Hofheinz, F.; Langner, J.; van den Hoff, J.

  • Magnetic Resonance in Medicine 72(2014), 1007-1014
    Online First (2013) DOI: 10.1002/mrm.25011

Establishment of a small animal tumour model for in vivo studies with low energy laser accelerated particles

Brüchner, K.; Beyreuther, E.; Baumann, M.; Krause, M.; Oppelt, M.; et al. (6 authors)

Fluorine containing 6,7-dialkoxybiaryl-based inhibitors for phosphodiesterase 10A: Synthesis and in vitro evaluation of inhibition potency, selectivity and metabolism

Schwan, G.; Asskar, G. B.; Höfgen, N.; Kubicova, L.; Funke, U.; et al. (12 authors)

Template-based approach for detecting motor task activation-related hyperperfusion in pulsed ASL data

Petr, J.; Ferré, J.-C.; Raoult, H.; Bannier, E.; Gauvrit, J.-Y.; et al. (6 authors)

  • Human Brain Mapping 35(2014)4, 1179-1189
    Online First (2013) DOI: 10.1002/hbm.22243

Production of 85Sr at a 18 MeV-cyclotron and purification for geochemical investigations

Mansel, A.; Gruhne, S.; Franke, K.; Fischer, S.

How plants cope with heavy metals

Viehweger, K.

2013

Assessment of the diagnostic performance of 18F-FDG-PET/CT for detection and characterization of solid renal malignancies.

Nakhoda, Z.; Torigian, D. A.; Saboury, B.; Hofheinz, F.; Alavi, A.

  • Open Access Logo Hellenic Journal of Nuclear Medicine 16(2013), 19-24

PET/MRI Imaging in High-Risk Sarcoma: First Findings and Solving Clinical Problems

Schuler, M. K.; Richter, S.; Beuthien-Baumann, B.; Platzek, I.; Kotzerke, J.; et al. (8 authors)

Pulmonary Blood Flow Increases in Damaged Regions Directly after Acid Aspiration in Rats

Richter, T.; Bergmann, R.; Knels, L.; Hofheinz, F.; Kasper, M.; et al. (9 authors)

Influence of rigid coregistration of PET and CT data on metabolic volumetry: a user's perspective

Steffen, I. G.; Hofheinz, F.; Rogasch, J. M. M.; Furth, C.; Amthauer, H.; et al. (6 authors)

Regioselective Synthesis of Trichloromethyl-Substituted Salicylates and Cyclohexenones by One-Pot Cyclizations of 1,3-Bis(trimethylsilyloxy)buta-1,3-dienes

Reimann, S.; Bunescu, A.; Petrosyana, A.; Sharif, M.; Erfle, S.; et al. (11 authors)

Comment on: "Transconvolution and the virtual positron emission tomograph: A new method for cross calibration in quantitative PET/CT imaging"

Hofheinz, F.; van den Hoff, J.

Development of fluorinated CB2 receptor agonists for PET studies

Lueg, C.; Schepmann, D.; Günther, R.; Brust, P.; Wünsch, B.

Influence and Compensation of Truncation Artifacts in MR-Based Attenuation Correction in PET/MR

Schramm, G.; Langner, J.; Hofheinz, F.; Petr, J.; Lougovski, A.; et al. (8 authors)

An automatic method for accurate volume delineation of heterogeneous tumors in PET

Hofheinz, F.; Langner, J.; Petr, J.; Beuthien-Baumann, B.; Steinbach, J.; et al. (7 authors)

Radionuclide impurities in [F-18]F- and [F-18]FDG for positron emission tomography

Koehler, M.; Degering, D.; Zessin, J.; Fuechtner, F.; Konheiser, J.

High-yield production of functional soluble single-domain antibodies in the cytoplasm of Escherichia coli

Zarschler, K.; Witecy, S.; Kapplusch, F.; Foerster, C.; Stephan, H.

Synthesis, Characterization, and Metabolism Studies of Fluspidine Enantiomers

Holl, K.; Falck, E.; Köhler, J.; Schepmann, D.; Humpf, H.-U.; et al. (7 authors)

Synthesis and radiopharmacological evaluation of 64Cu-labeled bombesin analogs featuring a bis(2-pyridylmethyl) 1,4,7-triazacyclononane chelator

Bergmann, R.; Ruffani, A.; Graham, B.; Spiccia, L.; Steinbach, J.; et al. (7 authors)

Design, synthesis, characterisation and in vitro studies of hydrophilic, colloidally stable, 64Cu(II)-labelled, ultra-small iron oxide nanoparticles in a range of human cell lines

Pombo Garcia, K.; Zarschler, K.; Barreto, J. A.; Hesse, J.; Spiccia, L.; et al. (7 authors)

Tissue transglutaminase: an emerging target for therapy and imaging

Pietsch, M.; Wodtke, R.; Pietzsch, J.; Löser, R.

Radiofluorination and biological evaluation of N-aryl-oxadiazolyl-propionamides as potential radioligands for PET imaging of cannabinoid CB2 receptors

Teodoro, R.; Moldovan, R.-P.; Lueg, C.; Günther, R.; Donat, C. K.; et al. (10 authors)

In vivo comparison of DOTA based 68Ga-labelled bisphosphonates for bone imaging in non-tumour models

Meckel, M.; Fellner, M.; Thieme, N.; Bergmann, R.; Kubicek, V.; et al. (6 authors)

Synthesis and radiopharmacological evaluation of a high-affinity and metabolically stabilized 18F-labeled bombesin analogue for molecular imaging of gastrin-releasing peptide receptor-expressing prostate cancer

Richter, S.; Wuest, M.; Krieger, S. S.; Rogers, B. E.; Friebe, M.; et al. (7 authors)

Quantitative Structure Property Relationship of logP for Radiopharmaceutical Technetium and Rhenium Complexes by using Molecular Dynamics Calculations

Yoshizuka, K.; Pietzsch, H.-J.; Seifert, S.; Stephan, H.

  • Open Access Logo Solvent Extraction Research and Development 20(2013), 15-27

Dynamic behavior of selected PET tracers in embryonated chicken eggs

Gebhardt, P.; Würbach, L.; Heidrich, A.; Heinrich, L.; Walther, M.; et al. (8 authors)

Fully automated radiosynthesis of both enantiomers of [18F]Flubatine under GMP conditions for human application

Patt, M.; Schildan, A.; Habermann, B.; Fischer, S.; Hiller, A.; et al. (13 authors)

Recent Trends in Bioorthogonal Click-Radiolabeling Reactions Using Fluorine-18

Pretze, M.; Pietzsch, D.; Mamat, C.

Radiosynthesis and in vivo Evaluation of a 18F-Labelled Styryl-Benzoxazole Derivative for ß-Amyloid Targeting

Ribeiro Morais, G.; Kniess, T.; Bergmann, R.; Gano, L.; Abrunhosa, A.; et al. (7 authors)

Optimization of Pentadentate Bispidines as Bifunctional Chelators for 64Cu Positron Emission Tomography (PET)

Comba, P.; Hunoldt, S.; Morgen, M.; Pietzsch, J.; Stephan, H.; et al. (6 authors)

Effects of dopaminergic treatment on striatal dopamine turnover in de novo Parkinson disease

Storch, A.; Wolz, M.; Beuthien-Baumann, B.; Loehle, M.; Herting, B.; et al. (12 authors)

The computation of lipophilicities of 64Cu PET systems based on a novel approach for fluctuating charges

Comba, P.; Martin, B.; Sanyal, A.; Stephan, H.

Condensation of the dianion of ethyl acetoacetate with perfluoroalkyl iodides. Application to the synthesis of 3-perfluoroalkylsalicylic acids

Mamat, C.; Langer, P.

Automated preparation of [18F]AFP and [18F]BFP: Two novel bifunctional 18F-labeling building blocks for Huisgen-click

Pretze, M.; Mamat, C.

An Efficient Bioorthogonal Strategy Using CuAAC Click Chemistry for Radiofluorinations of SNEW Peptides and the Role of Copper Depletion

Pretze, M.; Kuchar, M.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; et al. (6 authors)

Design and Development of 99mTc-‘4 + 1’-Labeled Dextran-Mannose Derivatives as Potential Radiopharmaceuticals for Sentinel Lymph Node Detection

Giglio, J.; Fernandez, S.; Jentschel, C.; Pietzsch, H.-J.; Papadopoulos, M.; et al. (9 authors)

The PET-derived tumor-to-blood standard uptake ratio (SUR) is superior to tumor SUV as a surrogate parameter of the metabolic rate of FDG

van den Hoff, J.; Oehme, L.; Schramm, G.; Langner, J.; Lougovski, A.; et al. (8 authors)

Synthesis and radiopharmacological characterisation of a fluorine-18 labelled azadipeptide nitrile as potential PET Tracer for in vivo imaging of cysteine cathepsins

Löser, R.; Bergmann, R.; Frizler, M.; Mosch, B.; Dombrowski, L.; et al. (9 authors)

Use of 3-[18F]fluoropropanesulfonyl chloride as prosthetic agent for the radiolabelling of amines: Investigation of precursor molecules, labelling conditions and enzymatic stability of the corresponding sulfonamides

Löser, R.; Fischer, S.; Hiller, A.; Köckerling, M.; Funke, U.; et al. (8 authors)

Recent trends in malignant melanoma biomarker research

Pietzsch, J.; Tandler, N.; Mosch, B.

  • Clinical Laboratory International 37(2013), 6-8

4-[18F]Fluoro-N-methyl-N-(propyl-2-yn-1-yl)benzenesulfonamide ([18F]F-SA): a versatile building block for labeling of peptides, proteins and oligonucleotides with fluorine-18 via Cu(I)-mediated click chemistry

Ramenda, T.; Steinbach, J.; Wuest, F.

Dual time point based quantification of metabolic uptake rates in 18F-FDG PET

van den Hoff, J.; Hofheinz, F.; Oehme, L.; Schramm, G.; Langner, J.; et al. (8 authors)

Anti-tumor effects of peptide analogues targeting neuropeptide hormone receptors on mouse pheochromocytoma cells

Ziegler, C. G.; Eisenhofer, G.; Schally, A. V.; Gebauer, L.; Gondek, K.; et al. (11 authors)

Synthesis and Evaluation of Novel 18F-Labeled Spirocyclic Piperidine Derivatives as σ1 Receptor Ligands for Positron Emission Tomography Imaging

Li, Y.; Wang, X.; Zhang, J.; Deuther-Conrad, W.; Xie, F.; et al. (13 authors)

  • Journal of Medicinal Chemistry 56(2013), 3478-3491
    DOI: 10.1021/jm301734g
    ISSN: 0022-2623

Dendrimers as Nb3+ ligands: effect of generation on the efficiency of the sensitized lanthanide emission

Pillai, Z. S.; Ceroni, P.; Kubeil, M.; Heldt, J.-M.; Stephan, H.; et al. (6 authors)

Radiolabeled COX-2 inhibitors for non-invasive visualization of COX-2 expression and activity - a critical update

Laube, M.; Kniess, T.; Pietzsch, J.

Ga-68- and Cu-64-Labeled NOTA-Albumin Conjugates for PET Sentinel Lymph Node Imaging

Schiller, E.; Bergmann, R.; Wunderlich, G.; Andreeff, M.; Jacob, A.; et al. (6 authors)

A fluoro versus a nitro derivative - a high-performance liquid chromatography study of two basic analytes with different RP and silica phases as basis for the separation of a positron emission tomography radiotracer

Wenzel, B.; Günther, R.; Brust, P.; Steinbach, J.

Synthesis of Short and Versatile Heterobifunctional Linkers for Conjugation Purposes of Bioactive Molecules with (Radio-)Labels

Heldt, J.-M.; Kerzendörfer, O.; Mamat, C.; Starke, F.; Pietzsch, H.-J.; et al. (6 authors)

Experimental hypoxia does not influence gene expression and protein synthesis of Eph receptors and ephrin ligands in human melanoma cells in vitro.

Reissenweber, B.; Mosch, B.; Pietzsch, J.

Inactivation of HNSCC Cells by 90Y-Labeled Cetuximab Strictly Depends on the Number of Induced DNA Double-Strand Breaks

Saker, J.; Kriegs, M.; Zenker, M.; Heldt, J.-M.; Eke, I.; et al. (13 authors)

Comments on “Comparative Study With New Accuracy Metrics for Target Volume Contouring in PET Image Guided Radiation Therapy”

van den Hoff, J.; Hofheinz, F.

  • IEEE Transactions on Medical Imaging 32(2013), 1146-1148
    Online First (2012) DOI: 10.1109/TMI.2012.2233209
    ISSN: 0278-0062

Investigations into the synthesis, radiofluorination and conjugation of a new [18F]fluorocyclobutyl prosthetic group and its in vitro stability using a tyrosine model system

Franck, D.; Kniess, T.; Steinbach, J.; Zitzmann-Kolbe, S.; Friebe, M.; et al. (7 authors)

Resistance of brain glucose metabolism to thiopental-induced CNS depression in newborn piglets

Bernd, W.; Eiselt, M.; Cumming, P.; Xiong, G.; Hinz, R.; et al. (8 authors)

Visualization of cyclooxygenase-2 using a 2,3-diarylsubstituted indole-based inhibitor and confocal laser induced cryofluorescence microscopy at 20 K in melanoma cells in vitro

Tondera, C.; Laube, M.; Wimmer, C.; Kniess, T.; Mosch, B.; et al. (7 authors)

Copper(II) chemistry of the functionalized macrocycle cyclam tetrapropionic acid

Comba, P.; Emmerling, F.; Jakob, M.; Kraus, W.; Kubeil, M.; et al. (8 authors)

Polyoxometalates as versatile enzyme inhibitors

Stephan, H.; Kubeil, M.; Emmerling, F.; Müller, C. E.

  • European Journal of Inorganic Chemistry 10-11(2013), 1585-1594
    Online First (2012) DOI: 10.1002/ejic.201201224

Radiosynthesis and first evaluation in mice of [18F]NS14490 for molecular imaging of α7 nicotinic acetylcholine receptors

Rötering, S.; Scheunemann, M.; Fischer, S.; Hiller, A.; Peters, D.; et al. (7 authors)

Synthesis and biological evaluation of 18F labeled fluoro-oligo-ethoxylated 4-benzylpiperazine derivatives for sigma-1 receptor imaging

Wang, X.; Li, Y.; Deuther-Conrad, W.; Xie, F.; Chen, X.; et al. (12 authors)

[68Ga]NS3-RGD and [68Ga] Oxo-DO3A-RGD for imaging αvβ3 integrin expression: synthesis, evaluation, and comparison

Knetsch, P. A.; Petrik, M.; Rangger, C.; Seidel, G.; Pietzsch, H.-J.; et al. (8 authors)

Leitlinie für die Hirnperfusions-SPECT mit Tc-99m Radiopharmaka / Hirnperfusions-SPECT with 99mTc-labelled Radiopharmaceuticals DGN-Guidance (S1 Guideline)

Kranert, T.; Menzel, C.; Bartenstein, P.; Brust, P.; Coenen, H. H.; et al. (11 authors)

  • Nuklearmedizin 5(2013)52, 157-162

2-Carbaborane-3-phenyl-1H-indoles—Synthesis via McMurry Reaction and Cyclooxygenase (COX) Inhibition Activity

Laube, M.; Neumann, W.; Scholz, M.; Lönnecke, P.; Crews, B.; et al. (9 authors)

Impact of 5-lipoxygenase inhibitors on the spatiotemporal distribution of inflammatory cells and neuronal COX-2 expression following experimental traumatic brain injury in rats

Härtig, W.; Michalski, D.; Seeger, G.; Voigt, C.; Donat, C. K.; et al. (10 authors)

Radiosynthesis of racemic and enantiomerically pure (–)-[18F]flubatine – A promising PET radiotracer for neuroimaging of α4β2 nicotinic acetylcholine receptors

Fischer, S.; Hiller, A.; Smits, R.; Hoepping, A.; Funke, U.; et al. (10 authors)

PET/MR for therapy response evaluation in malignant lymphoma: initial experience

Platzek, I.; Beuthien-Baumann, B.; Langner, J.; Popp, M.; Schramm, G.; et al. (9 authors)

  • Open Access Logo Magnetic Resonance Materials in Physics, Biology and Medicine 26(2013)1, 49-55
    Online First (2012) DOI: 10.1007/s10334-012-0342-7

PET/MR in head and neck cancer: initial experience

Platzek, I.; Beuthien-Baumann, B.; Schneider, M.; Gudziol, V.; Langner, J.; et al. (9 authors)

  • Open Access Logo European Journal of Nuclear Medicine and Molecular Imaging 40(2013), 6-11
    Online First (2012) DOI: 10.1007/s00259-012-2248-z

Partial volume correction in arterial spin labeling using a Look-Locker sequence

Petr, J.; Schramm, G.; Hofheinz, F.; Langner, J.; Steinbach, J.; et al. (6 authors)

  • Magnetic Resonance in Medicine 70(2013), 1535-1543
    Online First (2012) DOI: 10.1002/mrm.24601

High specific activity 61Cu via 64Zn(p,α)61Cu reaction at low proton energies

Thieme, S.; Walther, M.; Preusche, S.; Rajander, J.; Pietzsch, H.-J.; et al. (7 authors)

Quantitative accuracy of attenuation correction in the Philips Ingenuity TF whole-body PET/MR system A direct comparison with transmission-based attenuation correction

Schramm, G.; Langner, J.; Hofheinz, F.; Petr, J.; Beuthien-Baumann, B.; et al. (9 authors)

  • Open Access Logo Magnetic Resonance Materials in Physics, Biology and Medicine 25(2013)1, 115-126
    Online First (2012) DOI: 10.1007/s10334-012-0328-5

Use of targeted therapy for refractory ALK-positive anaplastic large cell lymphoma as a bridging strategy prior to allogeneic transplantation

Ordemann, R.; Stöhlmacher, J.; Beuthien-Baumann, B.; Platzek, I.; van den Hoff, J.; et al. (11 authors)

Design, synthesis, and preliminary in vitro and in vivo pharmacological evaluation of 4-{4-[2-(4-(2-substitutedquinoxalin-3-yl)piperazin-1-yl)ethyl]phenyl}thiazoles as atypical antipsychotic agents

Chandra Sekhar, K. V. G.; Rao, V. S.; Deuther-Conrad, W.; Sridhar, D.; Nagesh, H. N.; et al. (8 authors)

2012

Cerebral blood flow quantification in the rat: a direct comparison of arterial spin labeling MRI with radioactive microsphere PET

Bos, A.; Bergmann, R.; Strobel, K.; Hofheinz, F.; Steinbach, J.; et al. (6 authors)

Feasibility of estimation of brain volume and 2-deoxy-2-F-18-fluoro-D-glucose metabolism using a novel automated image analysis method: Application in Alzheimer's disease

Musiek, E. S.; Saboury, B.; Mishra, S.; Chen, Y.; Reddin, J. S.; et al. (11 authors)

  • Hellenic Journal of Nuclear Medicine 15(2012), 190-196
    ISSN: 1790-5427

Exploratory prospective trial of hypoxia-specific PET imaging during radiochemotherapy in patients with locally advanced head-and-neck cancer

Zips, D.; Zöphel, K.; Abolmaali, N.; Perrin, R.; Abramyuk, A.; et al. (10 authors)

Flow cytometric cell-based assay to preselect antibody constructs for radionuclide conjugation

Ingargiola, M.; Dittfeld, C.; Runge, R.; Zenker, M.; Heldt, J.-M.; et al. (10 authors)

Synthesis and biological evaluation of a novel Tc-99m cyclopentadienyl tricarbonyl complex ([(Cp-R)Tc-99m(CO)(3)]) for sigma-2 receptor tumor imaging

Chen, X.; Cui, M. C.; Deuther-Conrad, W.; Tu, Y. F.; Ma, T.; et al. (14 authors)

Protein and non-protein biomarkers in melanoma: a critical update.

Tandler, N.; Mosch, B.; Pietzsch, J.

Functional arterial spin labeling: Optimal sequence duration for motor activation mapping in clinical practice

Raoult, H.; Ferré, J.-C.; Petr, J.; Bannier, E.; Stamm, A.; et al. (7 authors)

Synthesis, in silico, in vitro, and in vivo investigation of 5-[11C]methoxy-substituted sunitinib, a tyrosine kinase inhibitor of VEGFR-2

Caballero, J.; Muñoz, C.; Alzate-Morales, J. H.; Cunha, S.; Gano, L.; et al. (8 authors)

Cellular and molecular properties of 90Y-labeled cetuximab in combination with radiotherapy on human tumor cells in vitro

Saki, M.; Toulany, M.; Sihver, W.; Zenker, M.; Heldt, J.-M.; et al. (10 authors)

18F-Labeled phosphopeptide-cell-penetrating peptide dimers with enhanced cell uptake properties in human cancer cells

Richter, S.; Bouvet, V.; Wuest, M.; Bergmann, R.; Steinbach, J.; et al. (8 authors)

Synthesis and cytotoxicity of pyridine and quinoline oxorhenium(V) complexes with tridentate (NS2, S-3)/monodentate (s) coordination

Segal, I.; Zablotskaya, A.; Kniess, T.; Shestakova, I.

18F-labelled CCR1-receptor antagonist is not suitable for imaging of Alzheimer's disease

Beuthien-Baumann, B.; Holthoff, V.; Mäding, P.; Bergmann, R.; Pawelke, B.; et al. (9 authors)

Cannabinoid Receptor Type 2 (CB2) Selective N-Aryl-oxadiazolyl-propionamides: Synthesis, Radiolabeling, Molekular Modelling and Biological Evaluation

Rühl, T.; Deuther-Conrad, W.; Fischer, S.; Günther, R.; Hennig, L.; et al. (7 authors)

Synthesis and crystal structure of benzyl[(1S)-1-(5-amino-1,3,4-oxadiazol-2-yl)-2-phenylethyl]carbamate

Löser, R.; Nieger, M.; Gütschow, M.

Combined PET/MR systems: an overview and comparison of currently available options

Herzog, H.; van den Hoff, J.

  • Quarterly Journal of Nuclear Medicine and Molecular Imaging 56(2012), 247-267
    ISSN: 1824-4785

Improved anatomic visualization of a glomus caroticum tumour within the carotic bifurcation with combined 68Ga-DOTATATE PET/MRI

Beuthien-Baumann, B.; Platzek, I.; Lauterbach, I.; van den Hoff, J.; Schramm, G.; et al. (8 authors)

Fluorine-18-Radiolabeling and Radiopharmacological Characterization of a Benzodioxolylpyrimidine as a Radiotracer Targeting the Receptor Tyrosine Kinase EphB4

Mamat, C.; Mosch, B.; Neuber, C.; Köckerling, M.; Bergmann, R.; et al. (6 authors)

Novel 7α-alkoxy-17α-(4’-halophenylethynyl)estradiols as potential SPECT/PET imaging agents for estrogen receptor expressing tumors: synthesis and binding affinity evaluation

Neto, C.; Oliveira, M. C.; Gano Fernanda Marques, M. L.; Yasuda, T.; Thiemann, T.; et al. (7 authors)

Synthesis and characterization of novel tetrahedral copper(I) complexes comprising tridentate PNP-aminodiphosphines and tetradentate PN(X)P-substituted aminodiphosphines (X = O, S)

Peruzzo, V.; Pretzsch, C.; Tisato, F.; Porchia, M.; Refosco, F.; et al. (10 authors)

Synthesis, in vitro and in vivo characterization of novel 99mTc-‘4+1’-labeled 5-nitroimidazole derivatives as potential agents for imaging hypoxia

Giglio, J.; Fernández, S.; Pietzsch, H.-J. D.; Dematteis, S.; Moreno, M.; et al. (8 authors)

Design, Evaluation, and Comparison of Ghrelin Receptor Agonists and Inverse Agonists as Suitable Radiotracers for PET Imaging

Chollet, C.; Bergmann, R.; Pietzsch, J.; Beck-Sickinger, A. G.

Irradiation affects cellular properties and Eph receptor expression in human melanoma cells

Mosch, B.; Pietzsch, D.; Pietzsch, J.

A method for model-free partial volume correction in oncological PET

Hofheinz, F.; Langner, J.; Petr, J.; Beuthien-Baumann, B.; Oehme, L.; et al. (8 authors)

Radioiodinated sunitinib as a potential radiotracer for imaging angiogenesis - radiosynthesis and first radiopharmacological evaluation of 5-[125I]Iodo-sunitinib

Kuchar, M.; Oliveira, M. C.; Gano, L.; Santos, I.; Knieß, T.

Radiohalogenated 4-anilinoquinazoline-based EGFR-TK inhibitors as potential cancer imaging agents

Neto, C.; Fernandes, C.; Oliveira, M. C.; Gano, L.; Mendes, F.; et al. (7 authors)

Ecto-ATPase inhibition: ATP and adenosine release under physiological and ischemic in vivo conditions in the rat striatum

Melani, A.; Corti, F.; Stephan, H.; Müller, C. E.; Donati, C.; et al. (8 authors)

Study of differences in the VEGFR2 inhibitory activities between semaxanib and SU5205 using 3D-QSAR, docking, and molecular dynamics simulations

Munoza, C.; Adasmea, F.; Alzate-Morales, J. H.; Vergara-Jaquea, A.; Kniess, T.; et al. (6 authors)

Radiolabeled small molecule inhibitors of VEGFR – recent advances

Kniess, T.

Module-assisted preparation of 64Cu with high specific activity

Thieme, S.; Walther, M.; Pietzsch, H.-J.; Henniger, J.; Preusche, S.; et al. (7 authors)

SUV-measurements and patient-specific corrections thereof in pediatric Hodgkin-lymphoma: Is there a benefit for PPV in early response assessment by FDG-PET?

Furth, C.; Meseck, R. M.; Steffen, I. G.; Schoenberger, S.; Denecke, T.; et al. (12 authors)

Automatic volume delineation in oncological PET. Evaluation of a dedicated software tool and comparison with manual delineation in clinical data sets

Hofheinz, F.; Pötzsch, C.; Oehme, L.; Beuthien-Baumann, B.; Steinbach, J.; et al. (7 authors)

Synthesis and Molecular Structure of tert-Butyl 4-(2-tert-butoxy-2-oxoethyl)piperazine-1-carboxylate

Mamat, C.; Flemming, A.; Köckerling, M.

The Synthesis and Molecular Structure of 2-(4-Methoxybenzyl)-4-nitro-2H-indazole

Ebert, K.; Köckerling, M.; Mamat, C.

Specific targeting of hypoxic tumor tissue with nitroimidazole-peptide conjugates

Splith, K.; Bergmann, R.; Pietzsch, J.; Neundorf, I.

Pyrrolovesamicols - Synthesis, structure and VAChT binding of two 4-fluorobenzoyl regioisomers

Wenzel, B.; Li, Y.; Kraus, W.; Sorger, D.; Sabri, O.; et al. (7 authors)

The Molecular Structure of 1,2:5,6-Di-O-isopropylidene-3-O-toluenesulfonyl-a-D-glucofuranose

Mamat, C.; Peppel, T.; Köckerling, M.

Imaging of the brain serotonin transporters (SERT) with 18F-labelled fluoromethyl-McN5652 and PET in humans

Hesse, S.; Brust, P.; Mäding, P.; Becker, G.-A.; Seese, A.; et al. (17 authors)

Development of radioligands for α7-nAChR imaging with positron emission tomography

Brust, P.; Peters, D.; Deuther-Conrad, W.

Synthesis, radiofluorination and pharmacological evaluation of fluoromethyl substituted spirocyclic PET tracers for labeling of σ1 receptors in the central nervous system and comparison with longer homologues

Maisonial, A.; Grosse Maestrup, E.; Wiese, C.; Hiller, A.; Schepmann, D.; et al. (9 authors)

Radiosynthesis and Radiotracer Properties of a 7-(2-[F-18]Fluoroethoxy)-6-methoxy-pyrrolidinylquinazoline for Imaging of Phosphodiesterase 10A with PET

Funke, U.; Deuther-Conrad, W.; Schwan, G.; Maisonial, A.; Scheunemann, M.; et al. (9 authors)

Site-selective radiolabeling of peptides by 18F-fluorobenzoylation with [18F]SFB in solution and on solid phase - a comparative study

Kuchar, M.; Pretze, M.; Knieß, T.; Steinbach, J.; Pietzsch, J.; et al. (6 authors)

Effect of leukotriene inhibitors on evolution of experimental brain contusions

Voigt, C. L. M.; Donat, C. K.; Härtig, W.; Förschler, A.; Arendt, T.; et al. (7 authors)

Radiosynthesis of a 18F-labeled 2,3-diarylsubstituted indole via McMurry coupling for functional characterization of cyclooxygenase-2 (COX-2) in vitro and in vivo

Kniess, T.; Laube, M.; Bergmann, R.; Graf, F.; Steinbach, J.; et al. (7 authors)

2011

Suitability of bilateral filtering for edge-preserving noise reduction in PET

Hofheinz, F.; Langner, J.; Beuthien-Baumann, B.; Oehme, L.; Steinbach, J.; et al. (7 authors)

Synthesis of an 18F-labeled cyclin-dependent kinase-2 inhibitor

Svensson, F.; Kniess, T.; Bergmann, R.; Pietzsch, J.; Wuest, F.

  • Journal of Labelled Compounds and Radiopharmaceuticals 54(2011), 769-774
    DOI: 10.1002/jlcr.1922

S100A2 in cancerogenesis: a friend or a foe?

Wolf, S.; Haase-Kohn, C.; Pietzsch, J.

S100 proteins in health and disease

Pietzsch, J.

Influence of storage on the position of the germinal disc in the fertilized unincubated chicken egg

Burkhardt, A.; Meister, S.; Bergmann, R.; Koch, E.

Synthesis, colloidal stability and 64Cu labeling of iron oxide nanoparticles bearing different macrocyclic ligands

Barreto, J. A.; Matterna, M.; Graham, B.; Stephan, H.; Spiccia, L.

  • New Journal of Chemistry 35(2011), 2705-2712

Copper-mediated cross-linking of S100A4, but not of S100A2, results in proinflammatory effects in melanoma cells

Haase-Kohn, C.; Wolf, S.; Lenk, J.; Pietzsch, J.

Phosphopeptides with improved cellular uptake properties as ligands for the polo-box domain of polo-like kinase 1

Richter, S.; Neundorf, I.; Loebner, K.; Gräber, M.; Berg, T.; et al. (9 authors)

Comparison of dopamine turnover, dopamine influx constant and activity ratio of striatum and occipital brain with F-18-dopa brain PET in normal controls and patients with Parkinson's disease

Oehme, L.; Perick, M.; Beuthien-Baumann, B.; Wolz, M.; Storch, A.; et al. (11 authors)

  • European Journal of Nuclear Medicine and Molecular Imaging 38(2011), 1550-1559
    DOI: 10.1007/s00259-011-1819-8
    ISSN: 1619-7070

Impact of functionalized coligands on the pharmacokinetics of 99mTc(III) ‘4+1’ mixed-ligand complexes conjugated to bombesin

Künstler, J.-U.; Bergmann, R.; Gniazdowska, E.; Kozminski, P.; Walther, M.; et al. (6 authors)

Neue Entwicklungen in der PET/CT Hybridbildgebung: Nutzen für die Strahlentherapie?

Hofheinz, F.; Perrin, R.; van den Hoff, J.; Zips, D.

Radiolabeling of phosphatidylserine-binding peptides with prosthetic groups N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide ([18F]FBAM) and N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)

Kapty, J.; Kniess, T.; Wuest, F.; Mercer, J. R.

Leitlinie für PET und SPECT–Untersuchungen von Hirntumoren mit radioaktiv markierten Aminosäuren

Langen, K.-J.; Bartenstein, P.; Brust, P.; Coenen, H. H.; Drzezga, A.; et al. (12 authors)

Maleimido-Functionalized NOTA Derivatives as Bifunctional Chelators for Site-Specific Radiolabeling

Förster, C.; Schubert, M.; Pietzsch, H.-J.; Steinbach, J.

Long-Acting Lipidated Analogue of Human Pancreatic Polypeptide Is Slowly Released into Circulation

Bellmann-Sickert, K.; Elling, C. E.; Madsen, A. N.; Little, P. B.; Lundgren, K.; et al. (10 authors)

  • Journal of Medicinal Chemistry 54(2011)8, 2658-2667
    DOI: 10.1021/jm101357e
    ISSN: 0022-2623

Synthesis, characterization and biological evaluation of [188Re(N)(cys∼)(PNP)]+/0 mixed-ligand complexes as prototypes for the development of 188Re(N)-based target-specific radiopharmaceuticals

Thieme, S.; Agostini, S.; Bergmann, R.; Pietzsch, J.; Pietzsch, H.-J.; et al. (9 authors)

Feasibility and performance of novel software to quantify metabolically active volumes and 3D partial volume corrected SUV and metabolic volumetric products of spinal bone marrow metastases on 18F-FDG-PET/CT.

Torigian, D. A.; Lopez, R. F.; Alapati, S.; Bodapati, G.; Hofheinz, F.; et al. (8 authors)

  • Open Access Logo Hellenic Journal of Nuclear Medicine 14(2011)1, 8-14
    ISSN: 1108-1430

Visualization of the focus in congenital hyperinsulinism by intraoperative sonography

von Rohden, L.; Mohnike, K.; Mau, H.; Eberhard, T.; Mohnike, W.; et al. (10 authors)

Cathepsin S inhibitors: WO2010070615

Löser, R.

Synthesis and evaluation of 1,5-diaryl-substituted tetrazoles as novel selective cyclooxygenase-2 (COX-2) inhibitors

Al-Hourani, B. J.; Sharma, S. K.; Mane, J. Y.; Tuszynski, J.; Baracos, V.; et al. (9 authors)

Imidazole Containing Bispidine Ligands: Synthesis, Structure and Cu(II)-Complexation

Walther, M.; Matterna, M.; Juran, S.; Fähnemann, S.; Stephan, H.; et al. (7 authors)

  • Zeitschrift für Naturforschung Section B - A Journal of Chemical Sciences 66b(2011), 721-728

Expression, purification and fluorine-18 radiolabeling of recombinant S100A4: a potential probe for molecular imaging of receptor for advanced glycation endproducts in vivo?

Wolf, S.; Haase-Kohn, C.; Lenk, J.; Hoppmann, S.; Bergmann, R.; et al. (7 authors)

  • Amino Acids 41(2011), 809-820

Zwei oder vier Stunden [18F]FMISO-PET in Kopf-Hals-Karzinomen: Wann ist der Bildkontrast am höchsten?

Abolmaali, N.; Haase, R.; Koch, A.; Zips, D.; Steinbach, J.; et al. (8 authors)

Intraoperative Sonography: A Technique for Localizing Focal Forms of Congenital Hyperinsulinism in the Pancreas

von Rohden, L.; Mohnike, K.; Mau, H.; Eberhard, T.; Mohnike, W.; et al. (10 authors)

A 18F-labeled Fluorobutyl-substituted spirocyclic piperidine derivative as a selective radioligand for PET imaging of sigma1 receptors

Maisonial, A.; Große Maestrup, E.; Fischer, S.; Hiller, A.; Scheunemann, M.; et al. (11 authors)

A Novel Tetrabranched Neurotensin(8-13) Cyclam Derivative: Synthesis, 64Cu-Labeling and Biological Evaluation

Röhrich, A.; Bergmann, R.; Kretzschmann, A.; Noll, S.; Steinbach, J.; et al. (7 authors)

Nanomaterials: applications in cancer imaging and therapy

Barreto, J. A.; O'Malley, W.; Kubeil, M.; Graham, B.; Stephan, H.; et al. (6 authors)

Synthesis, structure determination and (radio-) fluorination of novel functionalized phosphanes suitable for the traceless Staudinger ligation

Mamat, C.; Franke, M.; Peppel, T.; Köckerling, M.; Steinbach, J.

Synthesis and biological evaluation of new [Tc(N)(PS)]-based mixed-ligand compounds useful in design of target-specific radiopharmaceuticas: the 2-methoxyphenylpiperazine dithiocarbamate derivatives as example

Bolzati, C.; Salvarese, N.; Carta, D.; Refosco, F.; Dolmella, A.; et al. (8 authors)

[18F]1-(3-fluoropropyl)piperazines as model compounds for the radiofluorination of pyrido[2,3-d]pyrimidines

Grosse-Gehling, P.; Wuest, F. R.; Peppel, T.; Köckerling, M.; Mamat, C.

Synthesis and biological evaluation of novel 4-benzylpiperazine ligands for sigma-1 receptor imaging

Li, Z.-J.; Ren, H.-Y.; Cui, M.-C.; Deuther-Conrad, W.; Tang, R.-K.; et al. (9 authors)

Cross-Coupling Reactions as Valuable Tool for the Preparation of PET Radiotracers

Pretze, M.; Große-Gehling, P.; Mamat, C.

In vitro binding profile and radiosynthesis of a novel 18F-labeled azaspirovesamicol analog as potential ligand for imaging of the vesicular acetylcholine transporter

Wenzel, B.; Hiller, A.; Fischer, S.; Sorger, D.; Deuther-Conrad, W.; et al. (9 authors)

  • Journal of Labelled Compounds and Radiopharmaceuticals 54(2011), 426-432
    DOI: 10.1002/jlcr.1891

High regiocontrol in the nucleophilic ring opening of 1-aralkyl-3,4-epoxypiperidines with amines – A short-step synthesis of 4-fluorobenzyltrozamicol and novel anilidopiperidines

Scheunemann, M.; Hennig, L.; Funke, U.; Steinbach, J.

Assessment of alpha 7 nicotinic acetylcholine receptor availability in juvenile pig brain with [18F]NS10743

Deuther-Conrad, W.; Fischer, S.; Hiller, A.; Becker, G.; Cumming, P.; et al. (10 authors)

  • European Journal of Nuclear Medicine and Molecular Imaging 38(2011)8, 1541-1549

Automated radiosynthesis of the thiol-reactive labeling agent N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide ([18F]FBAM)

Knieß, T.; Kuchar, M.; Pietzsch, J.

Synthesis, pharmacological activity and structure affinity relationships of spirocyclic σ1 receptor ligands with a (2-fluoroethyl) residue in 3-position

Große Maestrup, E.; Wiese, C.; Schepmann, D.; Brust, P.; Wünsch, B.

The serotonin transporter availability in untreated early-onset and late-onset patients with obsessive-compulsive disorder

Hesse, S.; Stengler, K.; Regenthal, R.; Patt, M.; Becker, G.-A.; et al. (15 authors)

Molecular imaging of σ receptors: synthesis and evaluation of the potent σ1 selective radioligand [18F]fluspidine

Fischer, S.; Wiese, C.; Grosse Maestrup, E.; Hiller, A.; Deuther-Conrad, W.; et al. (10 authors)

  • European Journal of Nuclear Medicine and Molecular Imaging 38(2011)3, 540-551

Traumatic Brain Injury Elicits Similar Alterations in α7 Nicotinic Receptor Density in Two Different Experimental Models

Hoffmeister, P.-G.; Donat, C. K.; Schuhmann, M. U.; Voigt, C.; Walter, B.; et al. (9 authors)

Enantioselective σ1 receptor binding and biotransformation of the spirocyclic PET tracer 1’-Benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofuran-1,4’-piperidine]

Wiese, C.; Große Maestrup, E.; Schepmann, D.; Grimme, S.; Humpf, H.-U.; et al. (7 authors)

Design, Synthesis and Preliminary in vitro and in vivo Pharmacological Evaluation of 2-{4-[4-(2,5-disubstituted thiazolyl)phenylethyl] piperazin-1-yl}-1,8-naphthyridine-3- carbonitriles as Atypical Antipsychotic Agents

Chandra Sekhar, K. V. G.; Rao, V. S.; Deuther-Conrad, W.; Reddy, A. S.; Brust, P.; et al. (6 authors)

Implementation of 89Zr production and in vivo imaging of B-cells in mice with 89Zr-labeled anti B-cell antibodies by small animal PET/CT

Walther, M.; Gebhardt, P.; Grosse-Gehling, P.; Würbach, L.; Irmler, I.; et al. (11 authors)

2010

Positron emission tomography 2008 in Germany: Results of the query and current status

Kotzerke, J.; Oehme, L.; Lindner, O.; Hellwig, D.; Bartenstein, P.; et al. (19 authors)

Combined correction of recovery effect and motion blur for SUV quantification of solitary pulmonary nodules in FDG PET/CT

Apostolova, I.; Wiemker, R.; Paulus, T.; Kabus, S.; Dreilich, T.; et al. (11 authors)

Modulation of Adrenal Aldosterone Release by Oxidative Modification of Low-Density Lipoprotein

Ansurudeen, I.; Pietzsch, J.; Graessler, J.; Ehrhart-Bornstein, M.; Saha, S.; et al. (7 authors)

Identification of transport processes in bioirrigated muddy sediments by [18F]fluoride PET (Positron Emission Tomography)

Roskosch, A.; Lewandowski, J.; Bergmann, R.; Wilke, F.; Brenner, W.; et al. (6 authors)

Noncovalent Tripeptidyl Benzyl- and Cyclohexyl-Amine Inhibitors of the Cysteine Protease Caspase-1

Löser, R.; Abbenante, G.; Madala, P. K.; Halili, M.; Le, G. T.; et al. (6 authors)

Antimalarial activity of azadipeptide nitriles

Löser, R.; Gut, J.; Rosenthal, P. J.; Frizler, M.; Gütschow, M.; et al. (6 authors)

Sugar-decorated dendritic nanocarriers: Encapsulation and release of the octahedral rhenium cluster complex [Re6S8(OH)6]4-

Kubeil, M.; Stephan, H.; Pietzsch, H.-J.; Geipel, G.; Appelhans, D.; et al. (11 authors)

Comparison of the stability of Y-90-, Lu-177- and Ga-68- labeled human serum albumin microspheres (DOTA-HSAM)

Wunderlich, G.; Schiller, E.; Bergmann, R.; Pietzsch, H.-J.

The traceless Staudinger ligation with fluorine-18: a novel and versatile labeling technique for the synthesis of PET-radiotracers

Pretze, M.; Wuest, F.; Peppel, T.; Köckerling, M.; Mamat, C.

Preparation, 99mTc-labeling and biodistribution studies of a PNA oligomer containing a new ligand derivative of 2,2′-dipicolylamine

Gasser, G.; Jäger, K.; Zenker, M.; Bergmann, R.; Steinbach, J.; et al. (7 authors)

Accessible silanol sites - beneficial for the RP-HPLC separation of constitutional and diastereomeric azaspirovesamicol isomers

Wenzel, B.; Fischer, S.; Brust, P.; Steinbach, J.

A novel Dibenzoazacyclooctyne precursor in regioselective Copper-free click chemistry. An innovative 3-step synthesis.

Starke, F.; Walther, M.; Pietzsch, H.-J.

  • Open Access Logo ARKIVOC (2010), 350-359
    ISSN: 1551-7012

Synthesis and Radiofluorination of Iodophenyl Esters as Tool for the Traceless Staudinger Ligation

Pretze, M.; Flemming, A.; Köckerling, M.; Mamat, C.

  • Zeitschrift für Naturforschung Section B - A Journal of Chemical Sciences 65(2010), 1128-1136

3D QSAR study, synthesis and in vitro evaluation of (+)-5-FBVM as potential PET radioligand for the Vesicular AcetylCholine Transporter (VAChT)

Kovac, M.; Mavel, S.; Deuther-Conrad, W.; Méheux, N.; Glöckner, J.; et al. (10 authors)

A new hexanuclear rhenium cluster complex with six terminal acetate ligands: Synthesis, structure, and properties of K4[Re6S8(CH3COO)6]·8H2O

Brylev, K. A.; Mironov, Y. V.; Fedorov, V. E.; Kim, S.-J.; Pietzsch, H.-J.; et al. (8 authors)

Novel 99mTc '4 + 1' peptide conjugates: Tuning the biodistribution by variation of coligands

Künstler, J.-U.; Seidel, G.; Bergmann, R.; Gniazdowska, E.; Walther, M.; et al. (11 authors)

Eph Receptors and Ephrin Ligands: Important Players in Angiogenesis and Tumor Angiogenesis

Mosch, B.; Reissenweber, B.; Neuber, C.; Pietzsch, J.

Cyclin-Dependent Kinase 4/6 (Cdk4/6) Inhibitors: Perspectives in Cancer Therapy and Imaging

Graf, F.; Mosch, B.; Koehler, L.; Bergmann, R.; Wuest, F.; et al. (6 authors)

  • Mini-Reviews in Medicinal Chemistry 10(2010), 527-539
    ISSN: 1389-5575

Synthesis and biological evaluation of a radioiodinated spiropiperidine ligand as a potential σ1 receptor imaging agent

Chen, R.-Q.; Li, Y.; Zhang, Q.-Y.; Jia, H.-M.; Deuther-Conrad, W.; et al. (10 authors)

  • Journal of Labelled Compounds and Radiopharmaceuticals 53(2010), 569-574
    DOI: 10.1002/jlcr.1777

Design, Synthesis and in Vitro Biological Evaluation of Reference Compounds of 123I and 99Tcm Labeled Indole Radiotracers for σ2 Receptor Imaging

Li, Y.; Jia, H.-M.; Deuther-Conrad, W.; Brust, P.; Steinbach, J.; et al. (6 authors)

  • Open Access Logo Journal of Nuclear and Radiochemistry 32(2010)2, 132-138

Synthesis of neurotensin(8-13)-phosphopeptide heterodimers via click chemistry

Richter, S.; Ramenda, T.; Bergmann, R.; Knieß, T.; Steinbach, J.; et al. (7 authors)

Effects of lateral fluid percussion injury on cholinergic markers in the newborn piglet brain

Donat, C. K.; Walter, B.; Kayser, T.; Deuther-Conrad, W.; Schliebs, R.; et al. (9 authors)

Alterations of cholinergic receptors and the vesicular acetylcholine transporter after lateral fluid percussion injury in newborn piglets

Donat, C. K.; Walter, B.; Deuther-Conrad, W.; Nieber, K.; Brust, R.; et al. (6 authors)

Novel Indole Derivatives as Potential Imaging Agents for Alzheimer’s Disease

Yu, L.; Scheunemann, M.; Deuther-Conrad, W.; Hiller, A.; Fischer, S.; et al. (11 authors)

Crystal structure of N-benzyl-4-fluorobenzamide, C14H12FNO, at 173 K

Mamat, C.; Flemming, A.; Köckerling, M.

Iodine-124: A Promising Positron Emitter for Organic PET Chemistry

Koehler, L.; Gagnon, K.; Mcquarrie, S.; Wuest, F.

Efficient preparation of 99mTc(III) ‘4+1’ mixed-ligand complexes for peptide labeling with high specific activity

Künstler, J.-U.; Seidel, G.; Pietzsch, H.-J.

Enantioseparation of vesamicol and novel vesamicol analogs by high-performance liquid chromatography on different chiral stationary phases

Wenzel, B.; Fischer, S.; Brust, P.; Steinbach, J.

Radiosynthesis and radiopharmacological evaluation of cyclin-dependent kinase 4 (Cdk4) inhibitors

Koehler, L.; Graf, F.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; et al. (6 authors)

Scavenger receptors are associated with cellular interactions of S100A12 in vitro and in vivo

Hoppmann, S.; Steinbach, J.; Pietzsch, J.

Effects of posture on regional pulmonary blood flow in rats as measured by PET

Richter, T.; Bergmann, R.; Pietzsch, J.; Közle, I.; Hofheinz, F.; et al. (8 authors)

Comment on "Developing DCE-CT to Quantify Intra-Tumor Heterogeneity in Breast Tumors With Differing Angiogenic Phenotype"

Abramyuk, A.; Wolf, G.; Hietschold, V.; Haberland, U.; van den Hoff, J.; et al. (6 authors)

Effects of cold sphere walls in PET phantom measurements on the volume reproducing threshold

Hofheinz, F.; Dittrich, S.; Pötzsch, C.; van den Hoff, J.

Improved Multimodality Imaging Using Alginate Molding in Xenograft Tumor Models

Strobel, K.; Bergmann, R.; Meister, S.; van den Hoff, J.; Pietzsch, J.

2009

Recent Application of Click Chemistry for the Synthesis of Radiotracers for Molecular Imaging

Mamat, C.; Ramenda, T.; Wuest, F.

  • Mini-Reviews in Organic Chemistry 6(2009), 21-34

Fluorine-18 labeling of phosphopeptides: a potential approach for the evaluation of phosphopeptide metabolism in vivo.

Richter, S.; Bergmann, R.; Pietzsch, J.; Ramenda, T.; Steinbach, J.; et al. (6 authors)

PET-based investigation of cerebral activation following intranasal trigeminal stimulation

Hummel, T.; Oehme, L.; van den Hoff, J.; Gerber, J.; Heinke, M.; et al. (7 authors)

Analysis of non-protein amino acids as specific markers of protein oxidation: the use of N(O,S)-ethoxycarbonyl ethyl ester and N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and GC-MS

Pietzsch, J.; Pietzsch, F.-J.; Kopprasch, S.

  • Trends in Chromatography 5(2009), 15-20

Neuronal Aneuploidy in Health and Disease: A Cytomic Approach to Understand the Molecular Individuality of Neurons

Arendt, T.; Mosch, B.; Morawski, M.

  • Open Access Logo International Journal of Molecular Sciences 10(2009), 1609-1627
    DOI: 10.3390/ijms10041609
    ISSN: 1422-0067

Radiolabelling of proteins with fluorine-18 via click chemistry

Ramenda, T.; Knieß, T.; Bergmann, R.; Steinbach, J.; Wüst, F.

  • Chemical Communications 48(2009), 7521-7523
    DOI: 10.1039/b916075b
    ISSN: 1359-7345

Influence of irradiation on metabolism and metastatic potential of B16-F10 melanoma cells

Mosch, B.; Müller, K.; Steinbach, J.; Pietzsch, J.

Prediction of clonogenic cell survival curves based on the number of residual DNA double strand breaks measured by γH2AX staining

Menegakis‌, A.; Yaromina‌, A.; Eicheler‌, W.; Dörfler, A.; Beuthien-Baumann, B.; et al. (8 authors)

PET-Tracer für die onkologische Diagnostik: Welche radiomarkierten Substanzen sind relevant?

Knieß, T.; Steinbach, J.

  • Onkologische Pharmazie 11(2009)4, 4-5
    ISSN: 1437-8825

NMR Studies and Crystal Structure Determinations of CF3 Group-containing Bicyclic phenolates

Mamat, C.; Reinke, H.; Langer, P.

  • Zeitschrift für Naturforschung Section B - A Journal of Chemical Sciences 64(2009)4, 423-426
    ISSN: 0932-0776

Autoradiographic studies of rhenium-188-hydroxyethylidine diphosphonate in normal skeleton and osteoblastic bone metastases in a rat model of metastatic prostate cancer

Liepe, K.; Geidel, H. H.; Bergmann, R.; Haase, M.; Runge, R.; et al. (6 authors)

InIII and GaIII Complexes of Sugar-Substituted Tripodal Trisalicylidene Imines: The First 68Ga-Labelled Sugar Derivative

Gottschaldt, M.; Bohlender, C.; Pospiech, A.; Görls, H.; Walther, M.; et al. (9 authors)

Quantitative myocardial perfusion PET combined with coronary anatomy derived from CT angiography: Validation of a new fusion and visualisation software

Fricke, H.; Elsner, A.; Weise, R.; Bolte, M.; van den Hoff, J.; et al. (8 authors)

Comparison of [18F]FDG uptake and distribution with hypoxia and proliferation in FaDu human squamous cell carcinoma (hSCC) xenografts after single dose irradiation

Bruechner, K.; Bergmann, R.; Santiago, A.; Mosch, B.; Yaromina, A.; et al. (10 authors)

Synthesis and characterization of rhenium and technetium-99m tricarbonyl complexes bearing the 4-[3-bromophenyl]quinazoline moiety as a biomarker for EGFR-TK imaging

Bourkoula, A.; Paravatou-Petsotas, M.; Papadopoulos, A.; Santos, I.; Pietzsch, H.-J.; et al. (9 authors)

Isomerism in tetrahedral rhenium cluster complexes [Re4Q4(PMe2sub>Ph)4X8]·nCH2Cl2 (Q = Se, X = Br; Q = Te, X = Cl, Br).

Efremova, O. A.; Mironov, Y. V.; Brylev, K. A.; Fedorov, V. E.; Pietzsch, H.-J.; et al. (6 authors)

Synthesis of Benzoate-Functionalized Phosphanes as Novel Building Blocks for the Traceless Staudinger Ligation

Mamat, C.; Flemming, A.; Köckerling, M.; Steinbach, J.; Wuest, F.

Reduction of Arteriosclerotic Nanoplaque Formation and Size by n-3 Fatty Acids in Patients after Valvular Defect Operation

Koppe, C.; Rodriguez, M.; Winkler, K.; Pietzsch, J.; Neumann, K.; et al. (9 authors)

  • Forschende Komplementärmedizin / Research in Complementary Medicine 16(2009), 237-245
    DOI: 10.1159/000229786

Direct labelling of peptides with 2-[F-18]fluoro-2-deoxy-D-glucose ([F-18]FDG)

Wuest, F.; Hultsch, C.; Berndt, M.; Bergmann, R.

Antiproliferative effect of ferrocifen drug candidateson malignant pleural mesothelioma cell lines

Zanellato, I.; Heldt, J.-M.; Vessieres, A.; Jaouen, G.; Osella, D.

Radiosynthesis of New [90Y]-DOTA-Based Maleimide Reagents Suitable for the Prelabeling of Thiol-Bearing L-Oligonucleotides and Peptides

Schlesinger, J.; Fischer, C.; Közle, I.; Vonhoff, S.; Klussmann, S.; et al. (8 authors)

SIMS measurement of oxygen content in gamma-TiAl single crystals and polycrystalline alloys with Nb addition

Oswald, S.; Hermanna, R.; Schmidt, B.

Fluorine-18 radiolabeling of native and oxidized proteins: An important tool in the pathophysiologists’ toolbox

Pietzsch, J.; Wuest, F.

  • Chimica Oggi - Chemistry Today 27(2009), 12-14

Synthesis and radiopharmacological investigation of 3-[4’-[18F]fluorobenzylidenyl]-indolin-2-one as possible tyrosine kinase inhibitor

Knieß, T.; Bergmann, R.; Kuchar, M.; Steinbach, J.; Wüst, F.

Two Coordination Modes of Bidentate Aminopyrazine Ligands in Cubane-type Cluster Complex Re4Te4Cl8(C4N3H4)4 . 2DMF

Efremova, O. A.; Mironov, Y. V.; Pietzsch, H.-J.; Stephan, H.; Perrin, C.; et al. (6 authors)

Molecular imaging of α7 nicotinic acetylcholine receptors: design and evaluation of the potent radioligand [18F]NS10743

Deuther-Conrad, W.; Fischer, S.; Hiller, A.; Ostergaard Nielsen, E.; Brunicardi Timmermann, D.; et al. (9 authors)

Fluorine-18-radiolabeled S100A12: a potential probe for functional characterization of inflammatory processes in vivo

Hoppmann, S.; Richter, S.; Steinbach, J.; Pietzsch, J.

  • Inflammation Research 58(2009)Suppl. 2, S145-S146
    ISSN: 1023-3830

The First Octahedral Cluster Complexes With Terminal Formate Ligands: Synthesis, Structure, and Properties of K4[Re6S8(HCOO)6] and Cs4[Re6S8(HCOO)6]

Brylev, K. A.; Mironov, Y. V.; Kozlova, S. G.; Fedorov, V. E.; Kim, S.-J.; et al. (10 authors)

Hexadentate Bispidine Derivatives as Versatile Bifunctional Chelate Agents for Copper(II) Radioisotopes

Juran, S.; Walther, M.; Stephan, H.; Bergmann, R.; Steinbach, J.; et al. (8 authors)

On the multivariate nature of brain metabolic impairment in Alzheimer's disease

Salmon, E.; Kerrouche, N.; Perani, D.; Lekeu, F.; Holthoff, V.; et al. (9 authors)

Synthesis and cyclooxygenase inhibition of various (aryl-1,2,3-triazole-1-yl)-methanesulfonylphenyl derivatives

Wuest, F.; Tang, X.; Knieß, T.; Pietzsch, J.; Suresh, M.

Radiosynthesis and radiopharmacological evaluation of [N-methyl-11C]Org 34850 as a glucocorticoid receptor (GR)-binding radiotracer

Wüst, F.; Knieß, T.; Henry, B.; Peeters, B. W. M. M.; Wiegerinck, P. H. G.; et al. (7 authors)

Prediabetic and diabetic in vivo modification of circulating low density lipoprotein attenuates its stimulatory effect on adrenal mineralocorticoid secretion

Kopprasch, S.; Pietzsch, J.; Ansurudeen, I.; Graessler, J.; Krug, A. W.; et al. (7 authors)

Validation of 99mTc-labeled "4+1" fatty acids for myocardial metabolism and flow imaging Part 2: Subcellular distribution

Mirtschink, P.; Stehr, S. N.; Walther, M.; Pietzsch, J.; Bergmann, R.; et al. (13 authors)

Validation of 99mTc-labeled "4+1" fatty acids for myocardial metabolism and flow imaging Part 1: Myocardial extraction and biodistribution

Mirtschink, P.; Stehr, S. N.; Walther, M.; Pietzsch, J.; Bergmann, R.; et al. (13 authors)

Cell cycle regulating kinase Cdk4 as a potential target for tumor cell treatment and tumor imaging

Graf, F.; Köhler, L.; Knieß, T.; Wüst, F.; Mosch, B.; et al. (6 authors)

Human S100A12: a novel key player in inflammation?

Pietzsch, J.; Hoppmann, S.

Systematic comparison of two novel thiol-reactive prosthetic groups for 18F labeling of peptides and proteins with the acylation agent succinimidyl-4-[18F]fluorobenzoate [18F]SFB

Wüst, F.; Köhler, L.; Berndt, M.; Pietzsch, J.

  • Amino Acids 36(2009), 283-295
    ISSN: 0939-4451

Synthesis of modified pyrimidine bases and positive impact of the chemically reactive substituents on their in vitro antiproliferative activity

Noll, S.; Kralj, M.; Suman, L.; Stephan, H.; Piantanida, I.

2008

Additional PET/CT in week 5-6 of radiotherapy for patients with stage III non-small cell lung cancer as a means of dose escalation planning?

Gillham, C.; Zips, D.; Poenisch, F.; Evers, C.; Enghardt, W.; et al. (13 authors)

Radiation treatment planning in brain tumours Potential impact of 3-O-methyl-6-[18F]fluoro-L-DOPA and PET

Alheit, H.; Oehme, L.; Winkler, C.; Füchtner, F.; Hoepping, A.; et al. (8 authors)

Detailed Analysis Concerning the Biodistribution and Metabolism of Human Calcitonin-Derived Cell-Penetrating Peptides

Neundorf, I.; Rennert, R.; Franke, J.; Közle, I.; Bergmann, R.

3-(4-(6-Fluoroalkoxy-3,4-dihydroisoquinolin-2(1H)-yl)cyclohexyl)-1H-indole-5-carbonitriles for SERT imaging: chemical synthesis, evaluation in vitro and radiofluorination

Funke, U.; Fischer, S.; Hiller, A.; Scheunemann, M.; Deuther-Conrad, W.; et al. (7 authors)

Congenital hyperinsulinism: [18F]DOPA PET/CT scan of a focal lesion in the head of the pancreas

Kapoor, R. R.; Gilbert, C.; Mohnike, K.; Blankenstein, O.; Füchtner, F.; et al. (6 authors)

Rhenium and technetium complexes bearing quinazoline derivatives: progress towards a 99mTc biomarker for EGFR-TK imaging

Fernandes, C.; Santos, I. C.; Santos, I.; Pietzsch, H.-J.; Künstler, J.-U.; et al. (12 authors)

Effects of pioglitazone and/or simvastatin on low density lipoprotein subfractions in non-diabetic patients with high cardiovascular risk: A sub-analysis from the PIOSTAT study

Leonhardt, W.; Pfützner, A.; Müller, J.; Pietzsch, J.; Forst, T.; et al. (8 authors)

Factors affecting the specific activity of [18F]fluoride from a [18O]water target

Füchtner, F.; Preusche, S.; Mäding, P.; Zessin, J.; Steinbach, J.

First CoMFA Characterization of Vesamicol Analogs as Ligands for the Vesicular Acetylcholine Transporter

Szymoszek, A.; Wenzel, B.; Scheunemann, M.; Steinbach, J.; Schüürmann, G.

Synthesis and in vitro evaluation of new diphenyl ether derivatives as serotonin transporter ligands

Guo, Y.; Chen, X.; Jia, H.; Deuther-Conrad, W.; Brust, P.; et al. (8 authors)

Radiosynthesis of novel 18F-labelled derivatives of indiplon as potential GABAA receptor imaging tracers for PET

Fischer, S.; Hiller, A.; Scheunemann, M.; Deuther-Conrad, W.; Hoepping, A.; et al. (9 authors)

  • Journal of Labelled Compounds and Radiopharmaceuticals 51(2008), 123-131
    DOI: 10.1002/jlcr.1473

Synthesis and evaluation in vitro and in vivo of a 11C-labeled cyclooxygenase-2 (COX-2) inhibitor

Wüst, F.; Knieß, T.; Bergmann, R.; Pietzsch, J.

Factfile: S100A12

Pietzsch, J.

  • Open Access Logo Calcium Binding Proteins 3(2008), 18-21

Correlates of local cerebral blood flow (CBF) in normal pressure hydrocephalus patients before and after shunting—A retrospective analysis of [15O]H2O PET-CBF studies in 65 patients

Klinge, P. M.; Brooks, D. J.; Samii, A.; Weckesser, E.; van den Hoff, J.; et al. (9 authors)

PET und Bestrahlungsplanung - technische Aspekten / PET and Radiation Treatment Planning - Technical Aspects

Wolf, U.; Hofheinz, F.; Oehme, L.; van den Hoff, J.

PET in der Strahlentherapie: Perspektiven / PET in Radiation Oncology - Perspectives

Baumann, M.; Beuthien-Baumann, B.; Zips, D.

Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila; substrate specificity and requirement for virulence

Sansom, F. M.; Riedmaier, P.; Newton, H. J.; Dunstone, M. A.; Müller, C. E.; et al. (13 authors)

  • Journal of Biological Chemistry 283(2008)19, 12909-12918

Yttrium-86-labelled human serum albumin microspheres: relation of surface structure with in vivo stability

Schiller, E.; Bergmann, R.; Pietzsch, J.; Noll, B.; Sterger, A.; et al. (8 authors)

Synthesis and Application of [18F]FDG-maleimidehexyloxime ([18F]FDG-MHO): A [18F]FDG-based Prosthetic Group for the Chemoselective 18F-Labeling of Peptides and Proteins

Wüst, F.; Berndt, M.; Bergmann, R.; van den Hoff, J.; Pietzsch, J.

  • Bioconjugate Chemistry 19(2008)6, 1202-1210

Hydrophilic oxybathophenanthroline ligands: Synthesis and copper(II) complexation

Stephan, H.; Juran, S.; Born, K.; Comba, P.; Geipel, G.; et al. (8 authors)

An 86Y-Labeled Mirror-Image Oligonucleotide: Influence of Y-DOTA Isomers on the Biodistribution in Rats

Schlesinger, J.; Közle, I.; Bergmann, R.; Tamburini, S.; Bolzati, C.; et al. (12 authors)

Facile synthesis of various nitro-substituted derivatives of semaxinib (SU 5416)

Knieß, T.; Kuchar, M.; Wüst, F.

Radiolabeled glucocorticoids as molecular probes for imaging brain glucocorticoid receptors by means of positron-emission-tomography (PET)

Steiniger, B.; Knieß, T.; Bergmann, R.; Pietzsch, J.; Wüst, F.

  • Mini-Reviews in Medicinal Chemistry 8(2008)7, 728-739
    ISSN: 1389-5575

Radiosynthesis of n.c.a. sodium [18F]fluoroacetate and radiopharmacological characterization in rats and tumour-xenografted mice

Richter, S.; Bergmann, R.; Pietzsch, J.; Beuthien-Baumann, B.; Wüst, F.

  • Current Radiopharmaceuticals 1(2008)2, 103-109
    ISSN: 1874-4710

Evaluation of 18F- L-DOPA PET-CT for surgery in focal congenital hyperinsulinism

Barthlen, W.; Mau, H.; Koch, M.; Höhne, C.; Blankenstein, O.; et al. (10 authors)

  • Journal of Clinical Endocrinology and Metabolism 93(2008)3, 869-875

18F-DOPA Positron Emission Tomography for Preoperative Localization in Congenital Hyperinsulinism

Mohnike, K.; Blankenstein, O.; Minn, H.; Mohnike, W.; Füchtner, F.; et al. (6 authors)

Synthesis, Copper(II) Complexation, 64Cu-Labeling and Bioconjugation of a New Bis(2-pyridylmethyl) Derivative of 1,4,7-Triazacyclononane

Gasser, G.; Tjioe, L.; Graham, B.; Belousoff, M. J.; Juran, S.; et al. (10 authors)

  • Bioconjugate Chemistry 19(2008)3, 719-730

Expression, purification and fluorine-18 radiolabeling of recombinant S100 proteins - potential probes for molecular imaging of receptor for advanced glycation endproducts (RAGE) in vivo

Hoppmann, S.; Haase, C.; Richter, S.; Pietzsch, J.

Glycoxidation of low-density lipoprotein in impaired glucose tolerance: implications for the pathogenesis of diabetic vascular disease

Kopprasch, S.; Graessler, J.; Bornstein, S. R.; Pietzsch, J.

  • Vascular Disease Prevention 5(2008), 24-28
    ISSN: 1567-2700

Multicenter standardized FDG-PET diagnosis of mild cognitive impairment, Alzheimer's disease and other dementias

Mosconi, L.; Tsui, W. H.; Herholz, K.; Pupi, A.; Drzezga, A.; et al. (18 authors)

  • Journal of Nuclear Medicine 49(2008)3, 390-398

Investigations to the synthesis of n.c.a. [18F]FClO3 as electrophilic fluorinating agent

Hiller, A.; Fischer, C.; Jordanova, A.; Patt, J. T.; Steinbach, J.

Localized proton magnetic resonance spectroscopy of lipids in adipose tissue at high spatial resolution in mice in vivo

Strobel, K.; van den Hoff, J.; Pietzsch, J.

Fragmentation Reactions of Singly and Doubly Protonated Thiourea- and Sugar-substituted Cyclams and their Transition Metal Complexes

Felder, T.; Röhrich, A.; Stephan, H.; Schalley, C. A.

Labeling of Fatty Acid Ligands with the Strong Electrophilic Metal Fragment [99mTc(N)(PNP)]2+ (PNP = Diphosphane Ligand)

Cazzola, E.; Benini, E.; Pasquali, M.; Mirtschink, P.; Walther, M.; et al. (10 authors)

Modified “4+1” Mixed Ligand Technetium Labeled Fatty Acids for Myocardial Imaging: Evaluation of Myocardial Uptake and Biodistribution

Mirtschink, P.; Stehr, S. N.; Pietzsch, H.-J.; Bergmann, R.; Pietzsch, J.; et al. (12 authors)

Aspects of 6-[18F]fluoro-L-DOPA preparation: Deuterochloroform as a substitute solvent for Freon 11

Füchtner, F.; Zessin, J.; Mäding, P.; Wüst, F.

Practical experiences with the synthesis of [11C]CH3 trough gas phase iodination reaction using a TRACERlabFXC synthesis module

Knieß, T.; Rode, K.; Wüst, F.

2007

FDG-PET/CT in oncology: German Guideline

Krause, B. J.; Beyer, T.; Bockisch, A.; Delbeke, D.; Kotzerke, J.; et al. (24 authors)

Role of P2 purinergic receptors in synaptic transmission under normoxic and ischaemic conditions in the CA1 region of rat hippocampal slices

Coppi, E.; Pugliese, A. M.; Stephan, H.; Müller, C. E.; Pedata, F.

Experimental Evaluation of Functional Imaging for Radiotherapy

Zips, D.; Yaromina, A.; Schütze, C.; Wüllrich, K.; Krause, M.; et al. (16 authors)

Two mononuclear Tc complexes: [2,2′-(3-phenylpropylimino)- and [2,2′-(propylimino)-bis(ethanethiolato)](4-methoxybenzenethiolato)-oxidotechnetate(V)

Emmerling, F.; Kraus, W.; Noll, B.; Noll, S.; Pietzsch, H.-J.

(4-Methoxybenzenethiolato-κS)oxido-[2,2’-propylimino)-bis(ethanethiolato)- κ3S,N,S’]rhenium(V)

Kraus, W.; Emmerling, F.; Noll, B.; Noll, S.; Pietzsch, H.-J.

Fifty Years of radiopharmacy at Rossendorf

Spies, H.; Steinbach, J.

  • Journal of Labelled Compounds and Radiopharmaceuticals 50(2007), 895-902
    DOI: 10.1002/jlcr.1431

Factors influencing the formation of small dense low-density lipoprotein particles in dependence on the presence of the metabolic syndrome and on the degree of glucose intolerance

Julius, U.; Dittrich, M.; Pietzsch, J.

Correlations between MRS alterations and cerebral ammonia and glucose metabolism in citthotic patients with and without hepatic encephalopathy

Weissenborn, K.; Ahl, B.; Fischer-Wasels, D.; van den Hoff, J.; Hecker, H.; et al. (7 authors)

  • Journal of Gastroenterology and Hepatology 56(2007)12, 1736-1742
    ISSN: 1468-3288

PET/CT demonstrates increased myocardial FDG uptake following irradiation therapy

Zöphel, K.; Hölzel, C.; Dawel, M.; Hölscher, T.; Evers, C.; et al. (6 authors)

Carbohydration of 1,4,8,11-tetraazacyclotetradecane (cyclam): synthesis and binding properties toward concanavalin A

Stephan, H.; Röhrich, A.; Noll, S.; Steinbach, J.; Kirchner, R.; et al. (6 authors)

Expeditious synthesis of steroids containing a 2-methylsulfanyl-acetyl side chain as potential glucocorticoid receptor imaging agents

Wüst, F.; Carlson, K. E.; Katzenellenbogen, J. A.

Myocardial uptake and biodistribution of newly designed technetium-labelled fatty acid analogues

Heintz, A. C.; Jung, C. M.; Stehr, S. N.; Mirtschink, P.; Walther, M.; et al. (12 authors)

  • Nuclear Medicine Communications 28(2007)8, 637-647
    ISSN: 0143-3636

Aneuploidy and DNA Replication in the Normal Human Brain and Alzheimer’s Disease

Mosch, B.; Morawski, M.; Mittag, A.; Lenz, D.; Tarnok, A.; et al. (6 authors)

Tetrahydroquinoline and tetrahydroisoquinoline mixed ligand rhenium complexes with the SNS/S donor atom set

Zablotskaya, A.; Segal, I.; Lukevics, E.; Belyakov, S.; Spies, H.

Experimental hypoxia is a potent stimulus for radiotracer uptake in vitro: Comparison of different tumor cells and primary endothelial cells

Oswald, J.; Treite, F.; Haase, C.; Kampfrath, T.; Mäding, P.; et al. (8 authors)

Effect of increase of radiation dose on local control relates to pre-treatment FDG uptake in FaDu tumours in nude mice

Schütze, C.; Bergmann, R.; Yaromina, A.; Hessel, F.; Kotzerke, J.; et al. (8 authors)

Magnetic resonance imaging of bone metastases in patients with nonseminomatous germ cell tumors

Froehner, M.; Aikele, P.; Beuthien-Baumann, B.; Kittner, T.; Oehlschlaeger, S.; et al. (6 authors)

[18F]FBAM and [18F]FBOM: Novel Thiol-reactive prosthetic groups derived from 4-[18F]fluorobenzaldehyde

Vogler, L.; Berndt, M.; Pietzsch, J.; Wüst, F.

  • Journal of Labelled Compounds and Radiopharmaceuticals 50(2007), 1276-1286

Diagnostic impact of PET with 18F-FDG, 18F-DOPA and 3-O-methyl-6-[18F]fluoro-DOPA in recurrent or metastatic medullary thyroid carcinoma

Beuthien-Baumann, B.; Strumpf, A.; Zessin, J.; Bredow, J.; Kotzerke, J.

L-Type Amino Acid Transporters LAT1 and LAT4 in Cancer: Uptake of 3-O- Methyl-6-18F-Fluoro-L-Dopa (18F-OMFD) in Human Adenocarcinoma and Squamous Cell Carcinoma in vitro and in vivo

Haase, C.; Bergmann, R.; Füchtner, F.; Hoepping, A.; Pietzsch, J.

Cluster Core Controlled Reactions of Substitution of Terminal Bromide Ligands by Triphenylphosphine in Octahedral Rhenium Chalcobromide Complexes

Shestopalov, M. A.; Brylev, K. A.; Kozlova, S. G.; Fedorov, V. E.; Spies, H.; et al. (9 authors)

  • Journal of the American Chemical Society 129(2007), 3714-3721

Glycoxidised LDL isolated from subjects with impaired glucose tolerance increases CD36 and peroxisome proliferator-activator receptor gamma gene expression in macrophages

Graessler, J.; Pietzsch, J.; Westendorf, T.; Julius, U.; Bornstein, S. R.; et al. (6 authors)

Very stable 188Re-S4 chelates for labelling biomolecules, prepared with highly concentrated perrhenate eluates

Seifert, S.; Jentschel, C.; Bergmann, R.; Pietzsch, H.-J.; Wunderlich, G.; et al. (7 authors)

  • Nuklearmedizin 5(2007), 181-184
    ISSN: 0029-5566

Prefrontal Cortex Dysfunction and Depression in Atypical Parkinsonian Syndromes

Herting, B.; Beuthien-Baumann, B.; Pöttrich, K.; Donix, M.; Triemer, A.; et al. (10 authors)

[1-11C]Acetate uptake is not increased in renal cell carcinoma

Kotzerke, J.; Linné, C.; Meinhardt, M.; Steinbach, J.; Wirth, M.; et al. (8 authors)

Organometallic 99mTc(III) ‘4+1’ Bombesin(7-14) Conjugates: Synthesis, Radiolabeling and In Vitro/In Vivo Studies

Künstler, J.-U.; Veerendra, B.; Figueroa, S. D.; Sieckmann, G. L.; Rold, T. L.; et al. (8 authors)

  • Bioconjugate Chemistry 18(2007), 1651-1661

Azaspirovesamicols-Regioselective Synthesis and Crystal Structure Analysis of a Novel Class of Vesamicol Analogues as Potential Ligands for the Vesicular Acetylcholine Transporter

Wenzel, B.; Bats, J. W.; Scheunemann, M.; Steinbach, J.

Lipid transfer protein activities in subjects with impaired glucose tolerance

Julius, U.; Jauhiainen, M.; Ehnholm, C.; Pietzsch, J.

  • Clinical Chemistry and Laboratory Medicine 45(2007)2, 237-243
    ISSN: 1434-6621

Synthesis of 18F-labeled neurotensin(8-13) via copper-mediated 1,3-dipolar [3+2]cycloaddition reaction

Ramenda, T.; Bergmann, R.; Wüst, F.

  • Letters in Drug Design & Discovery 4(2007)4, 279-285
    ISSN: 1570-1808

Labeling of low-density lipoproteins using the 18F-labeled thiol-reactive reagent N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide [18F]FBAM

Berndt, M.; Pietzsch, J.; Wüst, F.

Effect of pseudophosphorylation and cross-linking by lipid peroxidation and advanced glycation end product precursors on tau aggregation and filament formation

Kuhla, B.; Haase, C.; Flach, K.; Lüth, H.-J.; Arendt, T.; et al. (6 authors)

Quantification of beta+ activity generated by hard photons by means of PET

Möckel, D.; Müller, H.; Pawelke, J.; Sommer, M.; Will, E.; et al. (6 authors)

Radiolabelling of multimeric neurotensin(8-13) analogues with the short-lived positron emitter fluorine-18

Hultsch, C.; Berndt, M.; Bergmann, R.; Wüst, F.

Synthesis of 18F-labelled stilbenes from 4-[18F]fluorobenzaldehyde using the Horner-Wadsworth-Emmons reaction

Gester, S.; Pietzsch, J.; Wüst, F.

  • Journal of Labelled Compounds and Radiopharmaceuticals 50(2007)2, 105-113
    DOI: 10.1002/jlcr.1172

Synthesis and radiopharmacological characterization of [11C]AL-438 as a nonsteroidal ligand for imaging brain glucocorticoid receptors

Wüst, F.; Knieß, T.; Bergmann, R.; Henry, B.; Pietzsch, J.

  • Bioorganic & Medicinal Chemistry Letters 17(2007), 4035-4039

Assessment of Lung Cancer Perfusion by Using Patlak Analysis: What Do We Measure?

van den Hoff, J.

  • Radiology 243(2007)3, 907-908

Blood Flow Quantification with Permeable Contrast Agents: A Valid Technique?

van den Hoff, J.

  • Radiology 243(2007)3, 909-910

Extraction of radio-labelled xanthine derivatives by artificial receptors – deep insight into the association behaviour

Bomkamp, M.; Siering, C.; Landrock, K.; Stephan, H.; Fröhlich, R.; et al. (6 authors)

Comparison of in vitro and in vivo properties of 99mTc-cRGD peptides labelled using different novel Tc-cores

Decristoforo, C.; Santos, I.; Pietzsch, H.-J.; Duatti, A.; Smith, C. J.; et al. (9 authors)

  • Quarterly Journal of Nuclear Medicine and Molecular Imaging 51(2007), 33-41

Synthesis and radiopharmacological characterization of 2β-carbo-2’-[18F]fluoroethoxy-3β-(4-bromo-phenyl)tropane ([18F]MCL-322) as a potential PET radiotracer for imaging the dopamine transporter (DAT)

Wüst, F.; Berndt, M.; Strobel, K.; van den Hoff, J.; Peng, X.; et al. (7 authors)

Synthesis and biological evaluation of a new type of 99mTechnetium-labeled fatty acid for myocardial metabolism imaging

Walther, M.; Jung, C.; Bergmann, R.; Pietzsch, J.; Rode, K.; et al. (15 authors)

  • Bioconjugate Chemistry 18(2007), 216-230
    ISSN: 10.1021/bc0601222

2006

Polarization of Human Hematopoietic Progenitors During Contact with Multipotent Mesenchymal Stromal Cells: Effects on Proliferation and Clonogenicity

Freund, D.; Bauer, N.; Boxberger, S.; Feldmann, S.; Streller, U.; et al. (10 authors)

  • Stem Cells and Development 15(2006), 815-829
    ISSN: 1547-3287

Advances in the Production, Processing and MicroPET Image Quality of Technetium-94m

Bigott, H. M.; Laforest, R.; Liu, X.; Ruangma, A.; Wüst, F.; et al. (6 authors)

  • Nuclear Medicine and Biology 33(2006)7, 923-933

Orbitofrontal Dysfunction Related to Both Apathy and Disinhibition in Frontotemporal Dementia

Peters, F.; Perani, D.; Herholz, K.; Holthoff, V.; Beuthien-Baumann, B.; et al. (11 authors)

  • Dementia and Geriatric Cognitive Disorders 21(2006), 373-379
    DOI: 10.1159/000091898

11C-Acetat positron-emission-tomography for occult prostate cancer

Froehner, M.; Beuthien-Baumann, B.; Wirth, M. P.

  • Urologic Oncology 24(2006), 410-411

Decomposition of metabolic brain clusters in the frontal variant of frontotemporal dementia

Salmon, E.; Kerrouche, N.; Herholz, K.; Perani, D.; Holthoff, V.; et al. (12 authors)

Neurotensin Receptors in Adeno- and Squamous Cell Carcinoma

Haase, C.; Bergmann, R.; Oswald, J.; Zips, D.; Pietzsch, J.

  • Open Access Logo Anticancer Research 26(2006), 3527-3534

Biodistribution and catabolism of 18F-labeled N-epsilon-fructoselysine as a model of Amadori products

Hultsch, C.; Hellwig, M.; Pawelke, B.; Bergmann, R.; Rode, K.; et al. (8 authors)

Fluorescein-labeled stable neurotensin derivatives

Maes, V.; Hultsch, C.; Kohl, S.; Bergmann, R.; Hanke, T.; et al. (6 authors)

  • Journal of Peptide Science 12(2006), 505-508

NMR-study on the structure and stability of 4-substituted aromatic iodosyl compounds

Hiller, A.; Patt, J. T.; Steinbach, J.

Polyoxometalates – a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors

Müller, C. E.; Iqbal, J.; Baqi, Y.; Zimmermann, H.; Röllich, A.; et al. (6 authors)

One-step reductive etherification of 4-[18F]fluoro-benzaldehyde with decaborane

Funke, U.; Jia, H.; Fischer, S.; Scheunemann, M.; Steinbach, J.

  • Journal of Labelled Compounds and Radiopharmaceuticals 49(2006), 745-755
    DOI: 10.1002/jlcr.1087

Synthesis and evaluation of novel multimeric neurotensin(8-13) analogs

Hultsch, C.; Pawelke, B.; Bergmann, R.; Wüst, F.

  • Bioorganic & Medicinal Chemistry 14(2006)17, 5913-5920

Preparation and Biological Characterization of Isomeric 188Re(V) Oxocomplexes with Tetradentate S4 Ligands Derived from DMSA for Labeling of Biomolecules

Seifert, S.; Heinrich, T.; Jentschel, C.; Smuda, C.; Bergmann, R.; et al. (6 authors)

Synthesis and biological evaluation of tricarbonyl Re(I) and Tc(I) complexes anchored by poly(azolyl)borates: application on the design of radiopharmaceuticals for the targeting of 5-HT1A receptors

Garcia, R.; Gano, L.; Maria, L.; Paulo, A.; Santos, I.; et al. (6 authors)

Bromo(tricarbonyl) (15-{[2-(methylthio-S)ethylthio-S} pentadecanoic acid)rhenium(l)

Kraus, W.; Walther, M.; Jung, C. M.; Emmerling, F.; Pietzsch, H.-J.

Tetrabutylammonium bis(2-amidobenzenethiolato-k2S,N)oxorhenate(V)

Gniazdowska, E.; Kraus, W.; Emmerling, F.; Spies, H.; Stephan, H.

Synthesis of 18F-labelled biphenyls via Suzuki cross-coupling with 4-[18F]fluoroiodobenzene

Steiniger, B.; Wüst, F.

  • Journal of Labelled Compounds and Radiopharmaceuticals 49(2006), 817-827

Two- and Threefold Intramolecular Bridging p-tert- Butylcalix[8]arene Triphosphates – Synthesis, Structure and Stereochemistry

Gloede, J.; Ozegowski, S.; Keitel, I.; Gruner, M.; Costisella, B.; et al. (8 authors)

  • Zeitschrift für Anorganische und Allgemeine Chemie (2006)632, 123-132

Chitosan-encapsulated Keggin anion [Ti2W10PO40]7-: Synthesis, characterization and cellular uptake studies

Meißner, T.; Bergmann, R.; Oswald, J.; Rode, K.; Richter, W.; et al. (10 authors)

Lack of efficacy of imatinib in a patient with metastatic Leydig cell tumor

Froehner, M.; Beuthien-Baumann, B.; Dittert, D.-D.; Schuler, U.; Wirth, M. P.

Synthesis and Radiopharmacological Characterisation of 86Y- and 68Ga-Labelled L-RNA Oligonucleotides as Molecular Probes for Positron Emission Tomography (PET)

Schlesinger, J.; Bergmann, R.; Klussmann, S.; Wüst, F.

  • Letters in Drug Design & Discovery 3(2006)5, 330-335

Optimized List-Mode Acquisition and Data Processing Procedures for ACS2 Based PET Systems

Langner, J.; Bühler, P.; Just, U.; Pötzsch, C.; Will, E.; et al. (6 authors)

Novel and Efficient Preparation of Precursor [188Re(OH2)3(CO)3]+ for the Labeling of Biomolecules

Park, S. H.; Seifert, S.; Pietzsch, H.-J.

  • Bioconjugate Chemistry 17(2006), 223-225

Synthesis of Azolyl Carboximidamides as Ligands for Zn(II) andCu(II): Application of the Zn(II) Complexes as Catalysts for theCopolymerization of Carbon Dioxide and Epoxides

Walther, M.; Wermann, K.; Lutsche, M.; Günther, W.; Görls, H.; et al. (6 authors)

  • Journal of Organic Chemistry 71(2006)4, 1399-1406

Neural correlates of anosognosia for cognitive impairment in Alzheimer's disease.

Salmon, E.; Perani, D.; Herholz, K.; Marique, P.; Kalbe, E.; et al. (12 authors)

Synthesis of a 11C-labelled taxane derivative by [1-11C]acetylation

Mäding, P.; Zessin, J.; Pleiß, U.; Füchtner, F.; Wüst, F.

  • Journal of Labelled Compounds and Radiopharmaceuticals 49(2006), 357-365
    DOI: 10.1002/jlcr.1059

11C-C bond formation by palladium-mediated cross-coupling of alkenylzirconocenes with [11C]methyl iodide

Wüst, F. R.; Berndt, M.

  • Journal of Labelled Compounds and Radiopharmaceuticals 49(2006)2, 91-100

A new molecular mechanics force field for the design of oxotechnetium(V) and oxorhenium(V) radiopharmaceuticals

Comba, P.; Daubinet, A.; Martin, B.; Pietzsch, H.-J.; Stephan, H.

  • Journal of Organometallic Chemistry 691(2006)11, 2495-2502

Octahedral rhenium cluster complexes with inner organic ligands: synthesis, structure and properties of [Re6Q8(3,5-Me2PzH)6]Br2·2(3,5-Me2PzH) (Q = S, Se)

Mironov, Y.; Bryleva, K.; Shestopalova, M.; Yarovoia, S.; Fedorova, V.; et al. (11 authors)

  • Inorganica Chimica Acta (2006)359, 1129-1134

188Re(III)-EDTA - a Multipurpose Starting Material for the Preparation of Relevant 188Re Complexes under Mild Conditions

Seifert, S.; Pietzsch, H.-J.

  • Applied Radiation and Isotopes 64(2006), 223-227

[11C]SMe-ADAM, an imaging agent for the brain serotonin transporter: Synthesis, pharmacological characterization and microPET studies in rats

Zessin, J.; Deuther-Conrad, W.; Kretzschmar, M.; Wüst, F.; Pawelke, B.; et al. (8 authors)

  • Nuclear Medicine and Biology 33(2006)1, 53-63

18F-Labelling of a potent nonpeptide CCR1 antagonist: Synthesis of 1-(5-chloro-2-{2-[(2R)-4-(4-[18F]fluorobenzyl)-2methylpiperazin-1-yl]-2-oxoethoxy}phenyl)urea in an automated module

Mäding, P.; Füchtner, F.; Johannsen, B.; Steinbach, J.; Hilger, C. S.; et al. (9 authors)

  • Journal of Labelled Compounds and Radiopharmaceuticals 49 (2006) 253-262

2005

[Re6Q7O(3,5-Me2PzH)6]Br2·3,5-Me2PzH (Q = S, Se) – new octahedral rhenium cluster complexes with organic ligands: original synthetic approach and unexpected ligand exchange in cluster core

Mironov, Y. V.; Shestopalov, M. A.; Brylev, K. A.; Yarovoi, A. S.; Romanenko, G. V.; et al. (12 authors)

  • European Journal of Inorganic Chemistry (2005), 657-661

Effect of Moderate Hypercapnic Hypoxia on Cerebral Dopaminergic Activity and Brain O2 Uptake in Intrauterine Growth–Restricted Newborn Piglets

Bauer, R.; Walter, B.; Vorwieger, G.; Fritz, A.; Füchtner, F.; et al. (7 authors)

Radioimmunotherapy of solid tumors by targeting extra domain B fibronectin: identification of the best-suited radioimmunoconjugate.

Berndorff, D.; Borkowski, S.; Sieger, S.; Rother, A.; Friebe, M.; et al. (10 authors)

  • Clinical Cancer Research 11(2005), 7053s-7063s

Heterogeneity of brain glucose metabolism in mild cognitive impairment and clinical progression to Alzheimer disease

Anchisi, D.; Borroni, B.; Franceschi, M.; Kerrouche, N.; Kalbe, E.; et al. (23 authors)

  • Archives of Neurology 62(2005)11, 1728-1733

Positron emission tomography in food sciences

Pietzsch, J.; van den Hoff, J.

Metabolite analysis in positron emission tomography studies: examples from food sciences

Pawelke, B.

Small animal positron emission tomography in food sciences

Bergmann, R.; Pietzsch, J.

Principles of quantitative positron emission tomography

van den Hoff, J.

Biodistribution and catabolism of 18F-labelled isopeptide N (varepsilon)-(gamma-glutamyl)-L-lysine

Hultsch, C.; Bergmann, R.; Pawelke, B.; Pietzsch, J.; Wüst, F.; et al. (7 authors)

Catabolism of native and oxidized low density lipoproteins (LDL): in vivo insights from small animal positron emission tomography studies

Pietzsch, J.; Bergmann, R.; Wüst, F.; Pawelke, B.; Hultsch, C.; et al. (6 authors)

Glucose-Induced Enhancement of Hemin-Catalyzed LDL Oxidation In Vitro and In Vivo

Julius, U.; Pietzsch, J.

  • Antioxidants and Redox Signaling 7(2005)11-12, 1507-1512

Pathological consequenses of systemic oxidative stress and dyslipidemia in impaired glucose tolerance and diabetes mellitus

Kopprasch, S.; Grässler, J.; Pietzsch, J.

  • Trends in Cell & Molecular Biology 1(2005), 1-14

Radiopharmakaforschung: Trends und neue Konzepte

Wüst, F.

In vivo metabolism of oxidized low density lipoproteins: Insights from small animal positron emission tomography (PET) studies

Pietzsch, J.; Bergmann, R.; Wüst, F.; van den Hoff, J.

  • Recent Research Developments in Molecular & Cellular Biochemistry 2(2005), 153-177

Novel triazinium-imidothioate zwitterions: intermediates in the reaction of [1,3,4]thiadiazolo[2,3-d][1,2,4]triazolo[1,5-a][1,3,5]-triazinium cations with amines

Wermann, K.; Walther, M.; Günther, W.; Görls, H.; Anders, E.

  • Tetrahedron 61(2005)3, 673-685

Kortikobasale Degeneration. Asymmetrisch mit Dystonie, Myoklonus und Apraxie

Herting, B.; Beuthien-Baumann, B.; Reichmann, H.

  • Der Neurologe und Psychiater 1-2(2005), 41-44

Module-assisted synthesis of the bifunctional labelling agent N-succinimidy 4-[18F]fluorobenzoate ([18F]SFB)

Mäding, P.; Füchtner, F.; Wüst, F.

  • Applied Radiation and Isotopes 63(2005), 329-332

{2-Carboxy-2-{bis[(2-thiolato-_S)ethyl]amino-_N}ethanthiolato-_S} (triphenylphosphin-_P)rhenium(III)

Schiller, E.; Kraus, W.; Reck, G.; Spies, H.; Pietzsch, H.-J.

  • Open Access Logo Acta Crystallographica Section E 61(2005), M1373-M1375
    ISSN: 1600-5368

A novel rhenium chelate system derived from dimercaptosuccinic acid for the selective labeling of biomolecules

Heinrich, T.; Kraus, W.; Pietzsch, H.-J.; Smuda, C.; Spies, H.

  • Inorganic Chemistry 44(2005)26, 9930-9937

Synthesis and biodistribution of an 18F-labelled resveratrol derivative for small animal positron emission tomography (PET)

Gester, S.; Wüst, F.; Pawelke, B.; Bergmann, R.; Pietzsch, J.

Aspects of positron emission tomography (PET) radiochemistry as relevant for food chemistry

Wüst, F.

Dramatic effect of the tridentate ligand on the stability of Tc-99m "3+1" oxo complexes bearing arylpiperazine derivatives

Fernandes, C.; Correia, D. G.; Gano, L.; Santos, I.; Seifert, S.; et al. (8 authors)

  • Bioconjugate Chemistry 16(2005)3, 660-668
    ISSN: 1043-1802

Disruption of unprecedented B-H...M agostic interactions: An alternative approach for labeling bioactive molecules

Garcia, R.; Paulo, A.; Domingos, A.; Santos, I.; Pietzsch, H.-J.

  • Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry 35(2005)1, 35-42

Synthesis and radiopharmacological evaluation of 2´-(4-fluorophenyl)-21-[18F]fluoro-20-oxo-11β,17α-dihydroxy-pregn-4-eno[3,2-c]pyrazole as potential glucocorticoid receptor ligand for positron emission tomography (PET)

Wüst, F.; Knieß, T.; Kretzschmar, M.; Bergmann, R.

  • Bioorganic & Medicinal Chemistry Letters 15(2005), 1303-1306

Synthesis and biological evaluation of S-[11C]methylated mercaptoimidazolde piperazinyl derivatives as potential radioligands for imaging 5-HT1A receptors by positron emission tomography (PET)

Garcia, R.; Xavier, C.; Paulo, A.; Santos, I.; Knieß, T.; et al. (7 authors)

  • Journal of Labelled Compounds and Radiopharmaceuticals 48(2005), 301-315

Synthesis and Binding Properties of Dendritic Oxybathophenanthroline Ligands towards Copper(II)

Stephan, H.; Geipel, G.; Bernhard, G.; Comba, P.; Rajaraman, G.; et al. (7 authors)

K6H2[TiW11CoO40]×13H2O, with a monotitanoundecatungstocobaltate(II) anion

Kraus, W.; Stephan, H.; Röllich, A.; Matéjka, Z.; Reck, G.

  • Open Access Logo Acta Crystallographica Section E 61(2005), i35-i37
    ISSN: 1600-5368

Synthesis of 18F-labelled COX-2 inhibitors via Stille Reaction with 4-[18F]fluoro-iodobenzene.

Wüst, F.; Höhne, A.; Metz, P.

  • Organic & Biomolecular Chemistry 3(2005), 503-507

Synthesis of 18F-labeled acyclic purine and pyrimidine nucleosides intended for monitoring gene expression

Grote, M.; Noll, B.; Noll, S.

  • Radiochimica Acta 93(2005)9-10, 585-588

N-Arylation of indoles with 4-[18F]fluoroiodobenzene: synthesis of 18F-labelled σ2 receptor ligands for positron emission tomography (PET)

Wüst, F.; Knieß, T.

  • Journal of Labelled Compounds and Radiopharmaceuticals 48(2005), 31-43
    DOI: 10.1002/jlcr.893

Regional cerebral metabolism in early Alzheimer’s disease with clinically significant apathy or depression

Holthoff, V.; Beuthien-Baumann, B.; Kalbe, E.; Lüdecke, S.; Lenz, O.; et al. (10 authors)

  • Biological Psychiatry 57(2005) 412-421

Functional imaging of vegetative state applying Single Photon Emission Tomography and Positron Emission Tomography

Beuthien-Baumann, B.; Holthoff, V. A.; Rudolf, J.

  • Neuropsychological Rehabilitation 15(2005)3/4, 276-282

Mixed-Ligand Rhenium-188 Complexes with Tetradentate/Monodentate NS3/P (‘4+1’) Coordination: Relation of structure with antioxidation stability

Schiller, E.; Seifert, S.; Tisato, F.; Refosco, F.; Bolzati, C.; et al. (8 authors)

  • Bioconjugate Chemistry 16(2005), 634-643

[Re6Q7O(3,5-Me2PzH)6]Br2*3,5-Me2PzH (Q = S, Se) - new octahedral rhenium cluster complexes with organic ligands: original synthetic approach and unexpected ligand exchange in cluster core

Mironov, Y. V.; Shestopalov, M. A.; Brylev, K. A.; Yarovoi, S. S.; Romanenko, G.; et al. (12 authors)

  • European Journal of Inorganic Chemistry (2005)4, 657-661

Pegylation of 1,4,8,11-Tetraazacyclotetradecane (Cyclam) and its Copper(II) Complexation

Stephan, H.; Geipel, G.; Bernhard, G.; Appelhans, D.; Tabuani, D.; et al. (7 authors)

  • Tetrahedron Letters 46(2005), 3209-3212

Messung von Phasen- und Konzentrationsverteilungen in Blasensäulen mit Positronen-Emissions-Tomographie

Zippe, C.; Hoppe, D.; Fietz, J.; Hampel, U.; Hensel, F.; et al. (8 authors)

2004

Functional Imaging of the Brain in Patients with Liver Cirrhosis.

Weissenborn, K.; Bokemeyer, M.; Ahl, B.-R.; Fischer-Wasels, D.; Giewekemeyer, K.; et al. (8 authors)

  • Metabolic Brain Disease 19(2004), 269-280

Effect of the hypoxic cell sensitizer isometronidazole on local control of two human Squamous Cell Carcinomas after fractionated irradiation.

Schreiber, A.; Krause, M.; Zips, D.; Dörfler, A.; Richter, K.; et al. (10 authors)

  • Strahlentherapie und Onkologie 180(2004), 1196-1201

Peritoneal strumosis.

Brogsitter, C.; Wonsak, A.; Würl, K.; Kotzerke, J.

  • European Journal of Nuclear Medicine and Molecular Imaging 31(2004), 1057-1058

Fluorine-18 radiolabeling of low-density lipoproteins: a potential approach for characterization and differentiation of metabolism of native and oxidized low-density lipoproteins in vivo.

Pietzsch, J.; Bergmann, R.; Rode, K.; Hultsch, C.; Pawelke, B.; et al. (7 authors)

  • Nuclear Medicine and Biology 31(2004), 1043-1050

Rhenium and technetium tricarbonyl complexes anchored by 5-HT1A receptor-binding ligands containing P,O/N donor atom sets

Palma, E.; Correia, J.; Domingos, A.; Santos, I.; Alberto, R.; et al. (6 authors)

Can [F18]FDG Positron emission tomography replace bone marrow biopsy in staging of patients with malignant lymphoma?

Naumann, R.; Beuthien-Baumann, B.

  • Clinical Lymphoma 5(2004), 127

The Influx of Neutral Amino Acids into the Porcine Brain During Development: A Positron Emission Tomography Study

Brust, P.; Vorwieger, G.; Walter, B.; Füchtner, F.; Stark, H.; et al. (8 authors)

  • Developmental Brain Research 152(2004), 241-253

The crucial role of the diphosphine heteroatom X in the stereochemistry and stabilization of the substitution-inert [M(N)(PXP)]2+ metal fragments (M = Tc, Re; PXP = diphosphine ligand)

Tisato, F.; Refosco, F.; Porchia, M.; Bolzati, C.; Bandoli, G.; et al. (11 authors)

  • Inorganic Chemistry 43(2004), 8617-8625

3-O-Methyl-6-18F-Fluoro-L-Dopa, a New Tumor Imaging Agent: Investigation of Transport Mechanism In Vitro

Bergmann, R.; Pietzsch, J.; Füchtner, F.; Pawelke, B.; Beuthien-Baumann, B.; et al. (7 authors)

  • Journal of Nuclear Medicine 45(2004), 2116-2122

Mikromilieu und Hypoxie im Bild

Baumann, M.; Krause, M.; Eicheler, W.; Petersen, C.; Zips, D.; et al. (9 authors)

  • Nova Acta Leopoldina NF 89, Nr. 337 (2004) 119-125

Is C-11-choline the most appropriate tracer for prostate cancer?

Zophel, K.; Kotzerke, J.

Regional differences in cerebral blood flow and cerebral ammonia metabolism in patients with cirrhosis

Ahl, B.; Weissenborn, K.; van den Hoff, J.; Fischer-Wasels, D.; Köstler, H.; et al. (7 authors)

Synthesis and biological evaluation of silylated mixed-ligand 99mTc complexes with the [PNS/S] donor atom set

Fernandes, C.; Knieß, T.; Gano, L.; Seifert, S.; Spies, H.; et al. (6 authors)

Cyclopentadienyl tricarbonyl complexes of 99mTC for the in vivo imaging of the serotonin 5-HT1A receptor in the brain

Saidi, M.; Kretzschmar, M.; Seifert, S.; Bergmann, R.; Pietzsch, H.-J.

Synthesis of 4-([18F]fluoromethyl)-2-chlorophenylisothiocyanate: A novel bifunctional 18F-labelling agent

Wüst, F.; Müller, M.; Bergmann, R.

  • Radiochimica Acta 92(2004)4-6, 349-353

No-carrier added synthesis of 18F-labelled nucleosides using Stille cross-coupling reactions with 4-[18F]fluoroiodobenzene

Wüst, F.; Knieß, T.

  • Journal of Labelled Compounds and Radiopharmaceuticals 47(2004), 457-468
    DOI: 10.1002/jlcr.834

Developmental changes in the activity of aromatic amino acid decarboxylase and catechol-O-methyl transferase in pigs: a positron emission tomography study

Brust, P.; Walter, B.; Hinz, R.; Füchtner, F.; Müller, M.; et al. (7 authors)

  • Neuroscience Letters, 364(2004)3, 159-163

Age-dependent effects of severe traumatic brain injury on cerebral dopaminergic activity in newborn and juvenile pigs

Walter, B.; Brust, P.; Füchtner, F.; Müller, M.; Hinz, R.; et al. (9 authors)

  • Journal of Neurotrauma 21(2004)8, 1076-1089

Neutral oxorhenium(V) and oxotechnetium(V) complexes with novel amide thioether dithiolate ligands derived from cysteine

Noll, B.; Hilger, C. S.; Leibnitz, P.; Spies, H.

  • Radiochimica Acta 92(2004)4-6, 271-276

Substantial impact of FDG PET imaging on the therapy decision in patients with early-stage Hodgkin´s lymphoma

Naumann, R.; Beuthien-Baumann, B.; Reiß, A.; Schulze, J.; Hänel, A.; et al. (12 authors)

  • British Journal of Cancer 90(2004), 620-625

Rhenium- and technetium-complexes with steroids as ligands for the estrogen receptor, progesterone receptor and androgen receptor

Wüst, F.

  • Current Topics in Steroid Research 4(2004), 197-205

The effect of garlic on arteriosclerotic nanoplaque formation and size

Siegel, G.; Malmsten, M.; Pietzsch, J.; Schmidt, A.; Buddecke, E.; et al. (8 authors)

  • Phytomedicine 11(2004), 24-35

Coexpression of Herpesviral Thymidine Kinase Reporter Gene for Nonivasive Monitoring of Therapeutic Gene Transfer - In Vivo- and Initial In Vivo-Evaluation

Anton, M.; Wittermann, C.; Haubner, R.; Simoes, M.; Reder, S.; et al. (15 authors)

  • Journal of Nuclear Medicine 45(2004)10, 1743-1746

Positron Emission Tomography of Cardiac Transgene Expression - Comparison of two Approaches Based on Herpesviral Thymidine Kinase Reporter Gene

Miyagawa, M.; Anton, M.; Haubner, R.; Simoes, M. S.; Städele, C.; et al. (16 authors)

  • Journal of Nuclear Medicine 45(2004) 11, 1917-1923

Changes in brain metabolism associated with remission in unipolar major depression

Holthoff, V.; Beuthien-Baumann, B.; Zündorf, G.; Triemer, A.; Lüdecke, S.; et al. (9 authors)

  • Acta Psychiatrica Scandinavica 110(2004), 184-194

An accurate method for correction of head movement in PET

Bühler, P.; Just, U.; Will, E.; Kotzerke, J.; van den Hoff, J.

  • IEEE Transaction on Medical Imaging 23(2004)9, 1176-1185

Novel Procedures for Preparing 99mTc(III) Complexes with Tetradentate/Monodentate Coordination of Varying Lipophilicity and Adaptation to 188Re Analogues

Seifert, S.; Künstler, J.-U.; Pietzsch, H.-J.; Pawelke, B.; Bergmann, R.; et al. (6 authors)

Modifications in cell cycle kinetics and in expression of G1 phase-regulating proteins in human amniotic cells after exposure to electromagnetic fields and ionizing radiation

Lange, S.; Viergutz, T.; Simkó, M.

  • Cell Proliferation 37(2004)5, 337-349

Synthesis, Characterization, and Biological Evaluation of Neutral Nitrido Technetium(V) Mixed Ligand Complexes Containing Dithiolates and Aminodiphosphines. A Novel System for Linking Technetium to Biomolecules

Bolzati, C.; Benini, E.; Cazzola, E.; Jung, C.; Tisato, F.; et al. (10 authors)

  • Bioconjugate Chemistry 15(2004), 628-637

Oxidativ modifizierte Lipoproteine und deren Antikörper bei Patienten mit Antiphospholipid-Syndrom

Roch, B.; Kopprasch, S.; Pietzsch, J.; Schröder, H.

The pivotal role of scavenger receptor CD36 and phagocyte-derived oxidants in oxidized low density lipoprotein-induced adhesion to endothelial cells

Kopprasch, S.; Pietzsch, J.; Westendorf, T.; Kruse, H.-J.; Graessler, J.

  • International Journal of Biochemistry and Cell Biology 36(2004)3, 460-471

The protective effects of HDL and its constituents against neutrophil respiratory bust activation by hypochlirite-oxidized LDL

Kopprasch, S.; Pietzsch, J.; Graessler, J.

  • Molecular and Cellular Biochemistry 258(2004), 121-127

Analysis of non-protein amino acids as specific markers of low density lipoprotein apolipoprotein B-100 oxidation in human atherosclerotic lesions: the use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and GC-MS

Pietzsch, J.; Bergmann, R.; Kopprasch, S.

  • Spectroscopy 18(2004),177-183

Analysis of 6-hydroxy-2-aminocaproic acid (HACA) as a specific marker of protein oxidation: The use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and gas chromatography/mass spectrometry

Pietzsch, J.; Bergmann, R.

  • Amino Acids 26(2004), 45-51

Therapy of malignant ascites in vivo by 211At-labelled microspheres

Bredow, J.; Kretzschmar, M.; Wunderlich, G.; Dörr, W.; Pohl, T.; et al. (7 authors)

  • Nuklearmedizin 43(2004), 63-68

Syntheses of Novel Modified Acyclic Purine and Pyrimidine Nucleosides as Potential Substrates of Herpes Simplex Type-1 Thymidine Kinase for Monitoring Gene Expression

Grote, M.; Noll, S.; Noll, B.; Johannsen, B.; Kraus, W.

2003

[N-methyl(11)C]meta-Hydroxyephedrine positron emission tomography in Parkinson's disease and multiple system atrophy

Berding, G.; Schrader, C. H.; Peschel, T.; van den Hoff, J.; Kolbe, H.; et al. (8 authors)

Brain perfusion and cerebral glucose metabolism in patients in persistent vegetative state

Beuthien-Baumann, B.; Handrick, W.; Schmidt, T.; Burchert, W.; Oehme, L.; et al. (9 authors)

  • Nucl. Med. Commun. 24 (2003) 643-650

What is evidence for positron emission tomography in the management of patients with indolent non-Hodgkin's lymphoma?

Naumann, R.; Beuthien-Baumann, B.

  • Clinical Lymphoma 4 (2003) 50-51

Differentiation between recurrent tumor or radiation necrosis in a child with anaplastic ependymoma after chemotherapy and radiation therapy

Beuthien-Baumann, B.; Hahn, G.; Winkler, C.; Heubner, G.

  • Strahlentherapie Onkologie (2003) 179: 819-822

Impact of asymmetric intrauterine growth restriction on organ function in newborn piglets

Bauer, R.; Walter, B.; Brust, P.; Füchtner, F.; Zwiener, U.

  • European Journal of Obstetrics and Gynecology and Reproductive Biology 110 (2003) S40-S49

3-O-Methyl-6-[18F]Fluoro-L-DOPA and its Evaluation in Brain Tumour Imaging

Beuthien-Baumann, B.; Bredow, J.; Burchert, W.; Füchtner, F.; Bergmann, R.; et al. (12 authors)

  • European Journal of Nuclear Medicine and Molecular Imaging (2003) 30: 1004-1008

S-[18F]fluoromethyl-(+)-McN5652, a PET Tracer for the Serotonin Transporter: Evaluation in Rats

Marjamäki, P.; Zessin, J.; Eskola, O.; Grönroos, T.; Haaparanta, M.; et al. (11 authors)

  • Synapse (2003) 47: 45-53

In vivo Measurement of the Serotonin Transporter with (S)-([18F]fluoromenthyl)-(+)-McN5652

Brust, P.; Hinz, R.; Kuwabara, H.; Hesse, S.; Zessin, J.; et al. (10 authors)

  • Neuropsychopharmacology (2003) 28, 2010-2019

Positron Emission Tomography Imaging of the Serotonin Transporter in the Pig Brain Using [11C](+)-McN5652 and S-([18F]fluoromethyl)-(+)-McN5652

Brust, P.; Zessin, J.; Kuwabara, H.; Pawelke, B.; Kretzschmar, M.; et al. (11 authors)

  • Synapse (2003) 47: 143-151

Autoradiographic analyses of 5-HT1A and 5-HT2A receptors after social isolation in mice

Schiller, L.; Jähkel, M.; Kretzschmar, M.; Brust, P.; Oehler, J.

  • Brain Research 980 (2003) 169-178

Validation of different chemilumigenic substrates for detecting extracellular generation of reactive oxygen species by phagocytes and endothelial cells

Kopprasch, S.; Pietzsch, J.; Graessler, J.

  • Luminescence (2003) 18: 268-273

Fortschritte in der Aminosäureanalytik: N(O,S)-Ethoxycarbonyl-(trifluoro)ethylester-Derivate

Pietzsch, J.

  • Bioforum 10/2003, 643-645

Measurement of 5-hydroxy-2-aminovaleric acid as a specific marker of iron-mediated oxidation of proline and arginine residues of low density lipoprotein aplipoprotein B-100 in human atherosclerotic lesions

Pietzsch, J.; Bergmann, R.

  • J Clin Pathol (2003) 56: 622-623

Flavonoide: Wirkmechanismen und neue Anwendungsmöglichkeiten (Teil 2)

Pietzsch, J.; Bergmann, R.; Wüst, F.

  • Bioforum (2003) 6:384-385

Flavonoide: Wirkmechanismen und neue Anwendungsmöglichkeiten (Teil 1)

Pietzsch, J.; Bergmann, R.; Wüst, F.

  • Bioforum (2003) 5: 289-291

Intraindividual comparison of [11C]acetate and [11C]choline PET for detection of metastases of prostate cancer

Kotzerke, J.; Volkmer, B. G.; Glatting, G.; van den Hoff, J.; Gschwend, J. E.; et al. (8 authors)

  • Nuklearmedizin (2003); 42 (1): 25-30

Improved Statistical Power of the Multilinear Reference Tissue Approach to the Quantification of Neuroreceptor Ligand Binding by Regularization

Buchert, R.; Wilke, F.; van den Hoff, J.; Mester, J.

  • Journal of Cerebral Blood Flow and Metabolism (2003) 23: 612-620

Accurate determination of metabolic rates from dynamic positron emission tomography data with very-low temporal resolution

Buchert, R.; van den Hoff, J.; Mester, J.

  • Journal of Computer Assisted Tomography (2003) 27 (4): 597-605

Möglichkeiten und Trends in Diagnostik und Therapie

Johannsen, B.

  • Pharm. Zeitg. 148, 2003, 2884-2893

Synthesis and Enzymatic Evaluation of Nucleosides Derived from 5-Iodo-2'-deoxyuridines

Knieß, T.; Grote, M.; Noll, B.; Johannsen, B.

  • Z. Naturforsch. 58b, 226-230 (2003)

Silylated mixed-ligand rhenium complexes with the [PNS/S] donor atom set

Knieß, T.; Fernandes, C.; Santos, I.; Kraus, W.; Spies, H.

  • Inorganica Chimica Acta 348 (2003) 237-241

Radiolabelling of isopeptide NEpsilon-(Gamma-glutamyl)-L-lysine by conjugation with N-succinimidyl-4-[18F]fluorobenzoate

Wüst, F.; Hultsch, C.; Bergmann, R.; Johannsen, B.; Henle, T.

  • Applied Radiation and Isotopes 59 (2003) 43-48

Increased cholesteryl ester transfer protein (CETP) activity in impaired glucose tolerance: relationship to high density lipoprotein metabolism

Pietzsch, J.; Fücker, K.

  • Croatian Medical Journal 44 (2): 171-177, 2003

Lack of association between serum paraoxonase (PON1) activities and increased oxidized LDL levels in impaired glucose tolerance and newly diagnosed diabetes mellitus

Kopprasch, S.; Pietzsch, J.; Kuhlisch, E.; Gräßler, J.

  • Journal of Clinical Endocrinology & Metabolism 2003; 88: 1711-1716

Analysis of 3-chlorotyrosine as a specific marker of protein oxidation: The use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and gas chromatography/mass spectrometry

Pietzsch, J.; Kopprasch, S.; Bergmann, R.

  • Rapid Commun. Mass Spectrom 17 (2003):767-770

Therapie mit Radionukliden

Wiegrebe, W.; Johannsen, B.

  • Pharm. Ztg. 148, 2003, 1610-1611

Radiopharmazie - Herausforderung und Chance für Apotheker

Wiegrebe, W.; Johannsen, B.

  • Pharm. Ztg. 148, 2003, 1526-1530

Alkyl-Substituted 2,6-Dioxadiazolylpyridines as Selective Extractants for Trivalent Actinides

Weigl, M.; Müllich, U.; Geist, A.; Gompper, K.; Zevaco, T.; et al. (6 authors)

  • Journal of Radioanalytical and Nuclear Chemistry, 256/3 (2003) 403-412

Where the anion extraction is going?

Gloe, K.; Stephan, H.; Grotjahn, M.

  • Chem. Eng. Technol. 26 (2003) 1107-1117

Towards promising oxoanion extractants: azacages and open-chain counterparts

Farrell, D.; Gloe, K.; Gloe, K.; Goretzki, G.; Mckee, V.; et al. (11 authors)

  • J. Chem. Soc., Dalton Trans. (2003) 1961-1968

Organic chemistry with the short-lived positron emitters 11C and 18F

Wüst, F. R.

  • Trends in Organic Chemistry (2003) 10: 61-70

A new Cryptophane Receptor Featuring Three endo-Carboxylic Acid Groups: Synthesis, Host Behavior and Structural Study

Roesky, C. E. O.; Weber, E.; Rambusch, T.; Stephan, H.; Gloe, K.; et al. (6 authors)

  • Chemistry, A European Journal 9/5 (2003) 1104-1112

Tumour specificity of 11C-acetate and 18F-FDG positron emission tomography in prostate cancer patients

Fricke, E.; Machtens, S.; Hofmann, M.; van den Hoff, J.; Bergh, S.; et al. (10 authors)

Aqueous synthesis of derivatized cyclopentadienyl complexes of technetium and rhenium directed towards radiopharmaceutical application

Bernard, J.; Ortner, K.; Spingler, B.; Pietzsch, H.-J.; Alberto, R.

  • Inorganic Chemistry 42 (2003) 1014-1022

Autoradiographic imaging of the serotonin ransporter in the brain of rats and pigs using S-([18F]Fluoromethyl)-(+)-McN5652

Kretzschmar, M.; Brust, P.; Zessin, J.; Cumming, P.; Bergmann, R.; et al. (6 authors)

  • European Neuropsychopharmacology 13 (2003) 387-397

Synthesis of 4-[18F]fluoroiodobenzene and its application in Sonogashira cross-coupling reactions

Wüst, F.; Knieß, T.

  • Journal of Labelled Compounds and Radiopharmaceuticals 2003, 46: 699-713

Efficient synthesis of the 18F-labelled amino acid 3-O-methyl-6-[18F]fluoro-L-DOPA

Füchtner, F.; Steinbach, J.

  • Applied Radiation and Isotopes 58 (2003) 575-578

Novel tumourtropic ester derivatives of 99mTc(V)-mesoDMSA with low affinity for bone tissue

Seifert, S.; Syhre, R.; Spies, H.; Johannsen, B.

  • Nuclear Medicine Communications (2003) 24: 1175-1183

Synthesis, characterization and biological evaluation of technetium(III) complexes with tridendate/bidendate S,E,S/P,S coordination (E = O, N(CH3), S): A novel approach to robust technetium chelates suitable for linking the metal to biomolecules

Pietzsch, H.-J.; Seifert, S.; Syhre, R.; Tisato, F.; Refosco, F.; et al. (7 authors)

  • Bioconjugate Chemistry 14 (2003) 136-143

A New Approach for a 11C-C Bond Formation: Synthesis of 17alpha-(3'-[11C]Prop-1-yn-1-yl)-3-Methoxy-3,17beta-Estradiol

Wüst, F.; Zessin, J.; Johannsen, B.

  • Journal of Labelled Compounds and Radiopharmaceuticals 46 (2003) 333-342

Synthesis of novel arylpyrazolo corticosteroids as potential ligands for imaging brain glucocorticoid receptors

Wüst, F.; Carlson, K. E.; Katzenellenbogen, J. A.

  • Steroids, 68 (2) (2003) 177-191

Molecular cloning and functional characterization of the OCTN2 transporter at the RBE4 cells, an in vitro model of the blood-brain barrier

Friedrich, A.; Prasad, P. D.; Freyer, D.; Et, A.

  • Brain Research 968: 69-79 2003

2002

Intraindividual comparison of two extracorporeal LDL apheresis methods: lipidfiltration and HELP

Julius, U.; Metzler, W.; Pietzsch, J.; Fassbender, T.; Klingel, R.

  • Int J Artif Organs 25 (2002): 1180-1188

Homocystein: Von der Spezialanalyse zum Routineparameter

Pietzsch, J.

  • Bioforum 9 (2002) 577-580

Fundamentals of quantitative PET data analysis

Willemsen, A. T. M.; van den Hoff, J.

  • Curr Pharm Des 8 (16) (2002) 1513-1526

Impaired glucose phosphorylation and transport in skeletal muscle cause insulin resistance in HIV-1-infected patients with lipodystrophy

Behrens, G. M. N.; Boerner, A.-R.; Weber, K.; van den Hoff, J.; Ockenga, J.; et al. (7 authors)

  • The Journal of Clinical Investigation 110 (2002) 1319-1327

Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET

Herholz, K.; Salmon, E.; Perani, D.; Baron, J.-C.; Holthoff, V.; et al. (25 authors)

  • NeuroImage 17 (2002) 302-316

FDG-PET in the pretherapeutic evaluation of primary squamous cell carcinoma of the oral cavity and the involvement of cervical lymph nodes

Hlawitschka, M.; Neise, E.; Bredow, J.; Beuthien-Baumann, B.; Haroske, G.; et al. (7 authors)

  • Molecular Imaging and Biology Vol. 4, No. 1 (2002) 91-98

Diagnostic value of 18F-FDG positron emission tomography for detection and treatment control of malignant germ cell tumors

Tsatalpas, P.; Beuthien-Baumann, B.; Kropp, J.; Manseck, A.; Tiepolt, C.; et al. (9 authors)

  • Urologia Internationalis 68 (2002) 157 - 163

Simultaneous occurrence of Hodgkin's lymphoma and eosinophilic granuloma: A potential pitfall in positron emission tomography imaging

Naumann, R.; Beuthien-Baumann, B.; Fischer, R.; Kittner, T.; Bredow, J.; et al. (8 authors)

  • Clinical Lymphoma Vol. 3, No. 2 (2002) 121-124

Synthesis and biological activity of ‚3+1' mixed ligand (3-thiapentane-1,5-dithiolato)oxorhenium(V) complexes bearing 1,2,3,4-tetrahydro(iso)quinoline and quinoline

Zablotskaya, A.; Segal, I.; Germane, S.; Shestakova, I.; Lukevics, E.; et al. (7 authors)

  • Applied Organometallic Chemistry 16 (2002) 550-555

In vivo evidence for increased oxidation of circulating LDL in impaired glucose tolerance

Kopprasch, S.; Pietzsch, J.; Kuhlisch, E.; Fuecker, K.; Temelkova-Kurktschiev, T.; et al. (9 authors)

  • Diabetes 51 (2002) 3102-3106

Synthesis of hydroxyl silylated rhenium and (99mTc)technetium ‚3+1'mixed ligand complexes

Knieß, T.; Spies, H.; Santos, I.; Zablotskaya, A.

  • J Label Compd Radiopharm 45 (2002) 629-636

Identification of tumor tissue by FTIR spectroscopy in combination with positron emission tomography

Richter, T.; Steiner, G.; Abu-Id, M. H.; Salzer, R.; Bergmann, R.; et al. (7 authors)

  • Vibrational Spectroscopy 28 (2002) 103-110

Quo vadis Anionenextraktion?

Gloe, K.; Stephan, H.; Grotjahn, M.

  • Chemie Ingenieur Technik 74 (2002) 767-777

Effect of hypoxia/hypercapnia on metabolism of 6-[18F]fluoro-L-DOPA in newborn piglets

Bauer, R.; Brust, P.; Walter, B.; Vorwieger, G.; Bergmann, R.; et al. (12 authors)

  • Brain Research 934 (2002) 22-33

Strahlende Stützen - Radioaktiv markierte Stents verhindern die Re-Stenose von Blutgefäßen

Ottow, S.; Noll, B.

  • Leibniz 1 (2002) 13-14

Tc and Re chelates of 8alpha-amino-6-methyl-ergoline: synthesis and affinity to the dopamine D2 receptor

Spies, H.; Noll, B.; Noll, S.; Findeisen, M.; Brust, P.; et al. (7 authors)

  • Bioorganic and Medicinal Chemistry 10 (2002) 3523-3528

Impaired glucose tolerance is not associated with lipid intolerance

Henkel, E.; Temelkova-Kurtschiev, T.; Köhler, C.; Pietzsch, J.; Leonhardt, W.; et al. (6 authors)

  • Diab Nutr Metab 15 (2002) 84-90

Synthese, Struktur, physikochemische und biologische Eigenschaften einiger schwefelhaltiger "3+1" Oxorhenium(V)-Komplexe

Zablotskaya, A.; Segal, I.; Kemme, A.; Germane, S.; Popelis, J.; et al. (8 authors)

  • Chem. Heterocycl. Compds. 4 (2002) 543-555

A novel technetium-99m radioligand for the 5-HT1A receptor derived from desmethyl-WAY-100635 (DWAY)

Heimbold, I.; Drews, A.; Syhre, R.; Kretzschmar, M.; Pietzsch, H.-J.; et al. (6 authors)

  • European Journal of Nuclear Medicine 29 (2002) 82-87

Syntheses and first crystal structures of rhenium complexes derived from omega-functionalized fatty acids as model compounds of technetium tracers for myocardial metabolism imaging

Jung, C. M.; Kraus, W.; Leibnitz, P.; Pietzsch, H.-J.; Kropp, J.; et al. (6 authors)

  • European Journal of Inorganic Chemistry (2002) 1219-1225

Synthesis and biological evaluation of technetium(III) mixed-ligand complexes with high affinity for the cerebral 5-HT1A receptor and the alpha1-adrenergic receptor

Drews, A.; Pietzsch, H.-J.; Syhre, R.; Seifert, S.; Varnäs, K.; et al. (12 authors)

  • Nuclear Medicine and Biology 29 (2002) 389-398

Development of technetium-99m-based CNS receptor ligands: have there been any advances?

Johannsen, B.; Pietzsch, H.-J.

  • Eur. J. Nucl. Med. 29 (2002) 263-275

Distribution of estrone sulfatase in rat brain determined by in vitro autoradiography with 16alpha-[18F]fluoroestradiol-3,17beta-disulfamate

Rodig, H.; Brust, P.; Römer, J.; Kasch, H.; Bergmann, R.; et al. (8 authors)

  • Applied Radiation and Isotopes 56 (2002) 773-780

Aspects of 6-[18F]fluoro-L-DOPA preparation: Precursor synthesis, preparative HPLC purification and determination of radiochemical purity

Füchtner, F.; Angelberger, P.; Kvaternik, H.; Hammerschmidt, F.; Peric Simovc, B.; et al. (6 authors)

  • Nuclear Medicine and Biology, 29 (2002) 477-481

Distribution of 16alpha-[18F]fluoro-estradiol-3,17beta-disulfamate (FESDS) in rats, tumour-bearing mice and piglets

Brust, P.; Rodig, H.; Römer, J.; Kasch, H.; Bergmann, R.; et al. (10 authors)

  • Applied Radiation and Isotopes 57 (2002) 687-695

Synthesis , biological and autoradiographic evaluation of a novel Tc-99m radioligand derived from WAY 100635 with high-affinity for the 5-HT1A receptor and the alpha1-adrenergic receptor

Heimbold, I.; Drews, A.; Kretzschmar, M.; Varnäs, K.; Hall, H.; et al. (12 authors)

  • Nuclear Medicine and Biology 29 (2002) 375-387

Biodistribution and catabolism of 18F-labeled neurotensin(8-13) analogs

Bergmann, R.; Scheunemann, M.; Heichert, C.; Mäding, P.; Wittrisch, H.; et al. (13 authors)

  • Nuclear Medicine and Biology 29 (2002) 61-72

2001

Synthesis and properties of triethyl(triphenyl)siloxyalkyl(aryl)thiolato(3-thiapentane-1,5-dithialato)oxorhenium(V)- potential brain seeking agents

Abedin, M. Z.; Spies, H.; Pietzsch, H.-J.; Zablotskaya, A.

  • Bangladesh Journal of Nuclear Medicine (2001) 1-6.

Synthesis and physico-chemical characterization of triorganylsiloxyalkyl monodentate ligands with free mercapto group.

Zablotskaya, A.; Segal, I.; Lukevics, E.; Knieß, T.; Spies, H.

  • Latv. Kim. Z. N4 (2001) 339-342

Prognostic value of positron emission tomography in the evaluation of post-treatment residual mass in patients with Hodgkin's disease and non-Hodgkin's lymphoma

Naumann, R.; Vaic, A.; Beuthien-Baumann, B.; Bredow, J.; Kropp, J.; et al. (8 authors)

  • British Journal of Haematology 115 (2001) 793-800

Synthesis and structural characterization of two cis-dioxorhenium(V) ReO2[SN][P] mixed-ligand complexes

Bouziotis, P.; Papagiannopoulou, D.; Pirmettis, I.; Pelecanou, M.; Raptopoulou, C. P.; et al. (11 authors)

  • Inorganica Chimica Acta 320 (2001) 174-177

Prophylaxis of restenosis with 186Re-labeled stents in a rabbit model

Tepe, G.; Dinkelborg, L. M.; Brehme, U.; Muschick, P.; Noll, B.; et al. (10 authors)

  • Circulation 104 (2001) 480-485

Synthesis and characterization of mixed-ligand oxorhenium(V) complexes with new [(PNO/S)(S)] donor atom sets

Correia, J. D. G.; Domingos, A.; Santos, I.; Spies, H.

  • J. Chem. Soc., Dalton Trans. (2001) 2245-2250

Simultaneous preparation of 16alpha-[18F]fluoroestradiol-sulphamates in an automated module. A high-yield procedure for 16alpha-[18F]fluoroestradiol-17beta-sulphamate

Römer, J.; Füchtner, F.; Steinbach, J.; Kasch, H.

  • Journal of Labelled Compounds and Radiopharmaceuticals 44 (2001) 689-700

Synthesis and host-guest properties of multi-crown-dendrimers towards sodium pertechnetate and mercury(II) chloride

Stephan, H.; Spies, H.; Johannsen, B.; Gloe, K.; Gorka, M.; et al. (6 authors)

  • Eur. J. Inorg. Chem. (2001) 2957-2963

Comparison of [18F]FHPG and [124/125I]FIAU for imaging herpes simplex virus type 1 tymidine kinase gene expression

Brust, P.; Haubner, R.; Friedrich, A.; Scheunemann, M.; Anton, M.; et al. (14 authors)

  • European Journal of Nuclear Medicine Vol.28, No. 6, (2001) 721-729

Synthesis of S-([18F]fluoromethyl)-(+)-McN5652 as a potential PET radioligand for the serotonin transporter

Zessin, J.; Eskola, O.; Brust, P.; Bergman, J.; Steinbach, J.; et al. (8 authors)

  • Nuclear Medicine and Biology 28 (2001) 857-863

Radio fluorination and positron emission tomography (PET) as a new approach to study the in vivo distribution and elimination of the advanced glycation endproducts Nepsilon-carboxymethyllysine (CML) and Nepsilon-carboxyethyllysine (CEL)

Bergmann, R.; Helling, R.; Heichert, C.; Scheunemann, M.; Mäding, P.; et al. (8 authors)

  • Nahrung/Food 45 (2001) 182-188

Reactivity of Technetium(I) Thioether Carbonyl Complexes towards Histidine - An EXAFS Study in Solution

Seifert, S.; Künstler, J.-U.; Gupta, A.; Funke, H.; Reich, T.; et al. (8 authors)

  • Inorganica Chimica Acta 322 (2001) 79-86

Mixed-ligand technetium(III) complexes with tetra-dendate/monodendate NS3/isocyanide coordination: A new nonpolar Technetium chelate system for the design of neutral and lipophilic complexes stable in vivo

Pietzsch, H.-J.; Gupta, A.; Syhre, R.; Leibnitz, P.; Spies, H.

  • Bioconjugate Chem. Vol.12 Nr. 4 (2001) 538-544

Synthesis and characterization of novel trigonal-bipyramidal technetium(III) mixed-ligand complexes with SES/S/P coordination (E = O, N(CH3), S)

Pietzsch, H.-J.; Tisato, F.; Refosco, F.; Leibnitz, P.; Drews, A.; et al. (7 authors)

  • Inorg. Chem. 40 (2001), 40, 59-64

Quantitative Radioluminography of Serotonin Uptake Sites in the Porcine Brain

Cumming, P.; Kretzschmar, M.; Brust, P.; Smith, D. F.

  • Synapse 39 (2001) 351-355

Intrauterine growth restriction induces up-regulation of cerebral aromatic amino acid decarboxylase activity in newborn piglets: [18F]fluorodopa positron-emission-tomographic study

Bauer, R.; Walter, B.; Vorwieger, G.; Bergmann, R.; Füchtner, F.; et al. (6 authors)

  • Pediatric Research 49 (2001) 474-480

Automated Synthesis of 16alpha-[18F]fluoroestradiol-3,17beta-disulphamate

Römer, J.; Füchtner, F.; Steinbach, J.; Kasch, H.

  • Applied Radiation and Isotopes 55 (2001) 631-639.

Ligand-Exchange Reaction of Labile "3+1" 99mTc(V) Complexes with SH Group-Containing Proteins

Seifert, S.; Gupta, A.; Syhre, R.; Spies, H.; Johannsen, B.

  • Appl. Radiat. Isot. 54 (2001) 637-644

Reactivity of 99mTc(V) "3+1" mixed-ligand complexes towards glutathione

Gupta, A.; Seifert, S.; Syhre, R.; Scheunemann, M.; Brust, P.; et al. (6 authors)

  • Radiochimica Acta 89 (2001) 43-49

2000

Permeation studies in vitro and in vivo of potential radiopharmaceuticals with affinity to neuro receptors

Friebe, M.; Suda, K.; Spies, H.; Syhre, R.; Berger, R.; et al. (9 authors)

  • Pharmaceutical Research, Vol. 17, No. 6 (2000) 754-760

'3+1' Mixed-ligand oxotechnetium(V) complexes with affinity for melanoma: Synthesis and Evaluation in vitro and in vivo

Friebe, M.; Mahmood, A.; Spies, H.; Berger, R.; Johannsen, B.; et al. (10 authors)

  • Journal of Medicinal Chemistry 43 (2000) 2745-2752

Neutral '3+1' mixed-ligand oxorhenium(V) complexes with tridentate [S,N,S] chelates and aminoalkanethiols: synthesis, characterization and structure determination

Friebe, M.; Spies, H.; Seichter, W.; Leibnitz, P.; Johannsen, B.

  • J. Chem. Soc, Dalton Trans. (2000) 2471-2475

Radiochemical synthesis and tissue distribution of Tc-99-labeled 7alpha-substituted estradiol complexes

Skaddan, M. B.; Wüst, F. R.; Jonson, S.; Syhre, R.; Welch, M. J.; et al. (7 authors)

  • Nuclear Medicine & Biology 27 (2000) 269-278

pH-controlled inclusion and release of oxyanions by denrimers bearing methyl orange moieties

Stephan, H.; Spies, H.; Johannsen, B.; Kaufmann, C.; Vögtle, F.

  • Organic Letters 2 (15) (2000) 2343-2346

Synthesis of 16alpha-[18F]fluorestradiol-3,17beta-disulphamate

Römer, J.; Füchtner, F.; Steinbach, J.

  • J. Labelled Cpd. Radiopharm. 43 (2000) 425-436

Glutathione interaction with SNS/S mixed ligand complexes of oxorhenium(V): Kinetic aspects and characterization of the products

Nock, B.; Maina, T.; Tsortos, A.; Pelecanou, M.; Raptopoulou, C. P.; et al. (12 authors)

  • Inorganic Chemistry 39 (2000) 4433-4441

EXAFS Analyses of Technetium(I) Carbonyl Complexes - Stability Studies in Solutions

Seifert, S.; Kuenstler, J.-U.; Gupta, A.; Funke, H.; Reich, T.; et al. (10 authors)

  • Radiochim. Acta 88 (2000) 239-245

Chemical and biological characterization of technetium(I) and rhenium(I) tricarbonyl complexes with dithioether ligands serving as linkers for coupling the Tc(CO)3 and Re(CO)3 moieties to biologically active molecules

Pietzsch, H.-J.; Gupta, A.; Reisgys, M.; Drews, A.; Seifert, S.; et al. (10 authors)

  • Bioconjugate Chem. 11 (2000) 414-424

Oxorhenium mixed-ligand complexes with the 2,6-dimercaptomethylpyridine ligand. Crystal structure of [2,6-dimercaptomethylpyridinato][p-methoxybenzenethiolato]oxorhenium(V)

Nock, B.; Pietzsch, H.-J.; Tisato, F.; Maina, T.; Leibnitz, P.; et al. (7 authors)

  • Inorg. Chim. Acta 304 (2000) 26-32

Untersuchung zur Strahlenbelastung des medizinischen Personals bei [18F]FDG-PET-Studien

Linemann, H.; Will, E.; Beuthien-Baumann, B.

  • Nuklearmedizin 39, 3/2000 (2000) 77-81

Stability Studies on 99mTechnetium(III) Complexes with Tridentate/Monodentate Thiol Ligands and Phosphine ("3+1+1" Complexes)

Seifert, S.; Drews, A.; Gupta, A.; Pietzsch, H.-J.; Spies, H.; et al. (6 authors)

  • Appl. Radiat. Isot. 53 (2000) 431-438

Preparation of Fluorine-18 labelled Sugars and Derivatives and their Application as Tracer for Positron-Emission-Tomography

Beuthien-Baumann, B.; Hamacher, K.; Oberdorfer, F.; Steinbach, J.

  • Carbohydrate Research 327 (2000) 107-118

Assessment of the in vitro and in vivo properties of a 99mTc-labeled inhibitor of the multidrug resistant gene product P-glycoprotein.

Bergmann, R.; Brust, P.; Scheunemann, M.; Pietzsch, H.-J.; Seifert, S.; et al. (7 authors)

  • Nucl. Med. Biol. 27 (2000) 135-141

Relation between brain tissue pO2 and dopamine synthesis of basal ganglia - A 18FDOPA-PET study in newborn piglets

Bauer, R.; Brust, P.; Walter, B.; Vorwieger, G.; Bergmann, R.; et al. (11 authors)

  • J. Perinat. Med. 28 (2000) 54-60

No-carrier-added 11C-labelling of benzenoid compounds in ring positions by condensation of nitro-[11C]methane with pyrylium salts

Mäding, P.; Steinbach, J.; Johannsen, B.

  • J. Labelled Cpd. Radiopharm. 43 (2000) 565-583

Synthesis of [1-11C]phenol

Mäding, P.; Steinbach, J.

  • J. Labelled Cpd. Radiopharm. 43 (2000) 557-563

Functional expression of the serotonin transporter in immortalized rat brain microvessel endothelial cells

Brust, P.; Friedrich, A.; Krizbai, I. A.; Bergmann, R.; Roux, F.; et al. (7 authors)

1999

Synthesis and binding affinities of novel Re-containing 7alpha-substituted estradiol complexes: Models for breast cancer imaging agents

Skaddan, M. B.; Wüst, F. R.; Katzenellenbogen, J. A.

  • J. Org. Chem. 64 (1999) Nr. 22, pp. 8108-8121

Study on the formation of mixed ligand oxorhenium and oxotechnetium complexes (SNS/S combination)

Papadopoulos, M.; Pirmettis, I.; Tsoukalas, C.; Nock, B.; Maina, T.; et al. (12 authors)

  • Inorg. Chim. Acta 295 (1999) 1-8

Lipophilic urea-functionalized dendrimers as efficient carriers for oxyanions

Stephan, H.; Spies, H.; Johannsen, B.; Klein, L.; Vögtle, F.

  • Chem. Commun., 1999, 1875-1876

Nicotinamide-substituted complexes as redox markers. 2. Synthesis of a 99Tc-dihydropyridine mixed-ligand complex and investigation of the stability in tissue homogenates

Rother, A.; Kniess, T.; Pütz, M.; Jungclas, H.; Spies, H.; et al. (6 authors)

  • Journal of Labelled Compounds and Radiopharmaceuticals 42, 673-681(1999)

First Application of fac-[99mTc(OH2)3(CO)3]+ in Bioorganometallic Chemistry: Design, Structure, and in Vitro Affinity of a 5-HT1A Receptor Ligand Labeled with 99mTc

Alberto, R.; Schibli, R.; Schubiger, P. A.; Abram, U.; Pietzsch, H.-J.; et al. (6 authors)

  • J. Am. Chem. Soc. 121, 25, 1999, 6076-6077

Nitridorhenium(V)-Komplexe mit Dimercaptobernsteinsäuredimethylester. Präparation, Charakterisierung und Kristallstruktur von [Re{NC(CH3)2PPhMe2}(DMSMe2)2]

Seifert, S.; Leibnitz, P.; Spies, H.

  • Zeitschrift fuer anorganische und allgemeine Chemie 1999, 625, 1037-1040

The stability of 2-[18F]fluoro-deoxy-D-glucose towards epimerisation under alkaline conditions

Meyer, G. J.; Matzke, K. H.; Hamacher, K.; Füchtner, F.; Steinbach, J.; et al. (7 authors)

  • Applied Radiation and Isotopes 51 (1999) 37-41

Effective coupling of Re/Tc-MAG3 complexes with amines and nucleobases in aprotic solvents.

Kniess, T.; Noll, S.; Noll, B.; Spies, H.; Johannsen, B.

  • Journal of Radioanalytical and Nuclear Chemistry, 240, No. 2 (1999), 657-660
    DOI: 10.1007/BF02349428

Melanoma affine Tc-99m complexes of N-(2-diethylaminoethyl)benzamides.

Eisenhut, M.; Mohammed, A.; Mier, W.; Friebe, M.; Haberkorn, U.

  • The Journal of Nuclear Medicine, 40 (1999) 120-121

Upregulation of the Aromatic Amino Acid Decarboxylase under Neonatal Asphyxia

Brust, P.; Bauer, R.; Vorieger, G.; Walter, B.; Bergmann, R.; et al. (9 authors)

Crystal and solution structure of oxo rhenium(V) complexes with cysteine and cysteine methyl ester

Kirsch, S.; Jankowsky, R.; Leibnitz, P.; Spies, H.; Johanssen, B.

Regional distribution of cerebral blood volume and cerebral blood flow in newborn piglets - effect of hypoxia / hypercapnia

Bauer, R.; Bergmann, R.; Walter, B.; Brust, P.; Zwiener, U.; et al. (6 authors)

Capillary electrophoresis of 99mtechnetium radiopharmaceuticals

Jankowsky, R.; Noll, B.; Johannsen, B.

  • Journal of Chromatography B, 724 (1999) 365-371

Synthesis and preliminary pharmacological investigations of 1-(1,2-dihydro-2-acenaphthylenyl)piperazine derivatives as potential atypical antipsychotic agents in mice

Srinivas, P.; Subramanian, A. R.; Brust, P.; Raghavan, S. A. V.; Rangisetty, J. B.; et al. (9 authors)

  • IL FARMACO 54 (1999) 567-572

Efficient phase transfer of pertechnetate with bicyclic guanidinium compounds

Stephan, H.; Berger, R.; Spies, H.; Johannsen, B.; Schmidtchen, F.-P.

  • Journal of Radioanalytical and Nuclear Chemistry 242 (2) (1999) 399-403

Long-distance transport of radionuclides between PET cyclotron and PET radiochemistry

Preusche, S.; Füchtner, F.; Steinbach, J.; Zessin, J.; Krug, H.; et al. (6 authors)

  • Appl. Rad. Isot. 51 (1999) 625-630

Synthesis and Autoradiographical Evaluation of a Novel High-Affinity Tc-99m Ligand for the 5-HT2A Receptor

Pietzsch, H.-J.; Scheunemann, M.; Kretzschmar, M.; Elz, S.; Pertz, H. H.; et al. (10 authors)

  • Nuclear Medicine and Biology, 26 (1999) 865-875

Synthesis and preliminary binding affinities of 1(1,2-dihydro-2-acenaphthylenyl)piperazine - a new arylpiperazine

Srinivas, P.; Brust, P.; Subramanian, A. R.; Raghavan, S. A. V.; Rangisetty, J. B.; et al. (7 authors)

  • Pharmaceutica Acta Helvetiae 74 (1999) 73-73

Synthesis of triphenylarsonium [11C ]methylide, a new 11C-Precursor. Application in the preparation of [2-11C]indole

Zessin, J.; Steinbach, J.; Johannsen, B.

  • Journal of Labelled Compounds and Radiopharmaceuticals 42 (1999) 725-736

Herstellung und Charakterisierung der Sulfamate von Estra-3,17xi-diolen. Schnelle Umsetzung von 16alpha-Fluorestradiol zum 16alpha-Fluorestradiol-3,17beta-disulfamat (Preparation and Characterization of the sulphamates of estra-3,17xi-diols. Rapid conversion of 16alpha-fluoroestradiol into 16alpha-fluoroestradiol-3,17beta-disulfamate)

Römer, J.; Steinbach, J.; Kasch, H.; Scheller, D.

  • J. Prakt. Chem. 341 (1999) 574-587

Nicotinamide-substituted complexes as redox markers 2. Synthesis of a 99Tc dihydropyridine mixed-ligand complex and investigation of the stability in tissue homogenates

Rother, A.; Knieß, T.; Pütz, M.; Jungclas, H.; Spies, H.; et al. (6 authors)

  • J. Labelled Cpd. Radiopharm. 42 (1999) 673-681

Synthesis of Novel Progestin-Rhenium Conjugates as Potential Ligands for the Progesterone Receptor

Wüst, F.; Skaddan, M. B.; Leibnitz, P.; Spies, H.; Katzenellenbogen, J. A.; et al. (6 authors)

Efficient Synthesis of Enantiomerically Pure Thioester Precursors of [11C] MCN-5652 from Racemic MCN-5652

Zessin, J.; Gucker, P.; Ametamey, S. M.; Steinbach, J.; Brust, P.; et al. (8 authors)

  • J. Labelled Cpd. Radiopharm. 42 (1999) 1301-1312

Automated Production of the PET Tracer 16 alpha-[18F] Fluoroestradiol for Breast Cancer Imaging

Römer, J.; Füchtner, F.; Steinbach, J.; Johannsen, B.

  • Nucl. Med. Biol. 26 (1999) 473-479

Synthesis and Reactions of New Oxorhenium(V) Complexes with Re-Halogen Bonds. X-Ray Crystal Structure of 3-(Benzyl)azapentane-1.5-dithiolato)iodo-Oxorhenium(V).

Fietz, T.; Leibnitz, P.; Spies, H.; Johannsen, B.

  • Polyhedron 18 (1999) 1793-1797

Radioligands for the Study of the 5-HT Transporter in Vivo

Brust, P.; Scheffel, U.; Szabo, Z.

  • IDrugs 1999 Vol 2 No 2 , Review Radioligands 129-145

Determination of Dissociation Constants of 99mTechnetium Radiopharmaceuticals by Capillary Electrophoresis

Jankowsky, R.; Friebe, M.; Noll, B.; Johannsen, B.

1998

Preparation and structural studies of neutral oxorhenium(V) complexes with D-pencillamine methyl ester

Kirsch, S.; Noll, B.; Spies, H.; Leibnitz, P.; Scheller, D.; et al. (7 authors)

  • J. Chem. Soc., Dalton Trans. (1998) 455-460

TROTEC-1 a new high affinity ligand for Labeling of the dopamine transporter

Hoepping, A.; Reisgys, M.; Brust, P.; Seifert, S.; Spies, H.; et al. (7 authors)

  • Journal of Medicinal Chemistry, 41(23) (1998) 4429-4432

Synthesis, Structure, Lipophilicity and Protonation Behaviour of Mixed Ligand Rhenium Chelates Functionalized by Amine Groups

Papadopoulos, M.; Pirmettis, I.; Raptopoulou, C.; Chiotellis, E.; Friebe, M.; et al. (8 authors)

Solution Structures of Rhenium (V) Oxo Peptide Complexes of Glycylglycylcysteine and Cysteinglycine as Studied by Capillary Electrophoresis and X-Ray Absorption Spectroscopy

Jankowsky, R.; Kirsch, S.; Reich, T.; Spies, H.; Johannsen, B.

Mrp1 Multidrug Resistance-Associated Protein and P-Glykoprotein Expression in Rat Brain Microvessel Endothelial Cells

Regina, A.; Koman, A.; Piciotti, M.; El Hafny, B.; Center, M. S.; et al. (8 authors)

Synthesis and Binding Affinities of New 17a-Substituted Estradiol-Rhenium n+1 Mixed-Ligand and Thioether-Carbonyl Complexes

Wüst, F.; Carlson, K. E.; Katzenellenbogen, J. A.; Spies, H.; Johannsen, B.

A Mixed-Ligand P,S,N-cis-Dioxorhenium(V) Complex by Ligand Exchange Reaction on trans-monooxo-trichloro-bis(triphenylphosphine)rhenium(V): Formation and Structural Studies

Friebe, M.; Jankowsky, R.; Spies, H.; Seichter, W.; Papadopoulos, M.; et al. (7 authors)

No Carrier Added Preparations of '3+1' Mixed-Ligand 99mTc Complexes

Seifert, S.; Pietzsch, H.-J.; Scheunemann, M.; Spies, H.; Syhre, R.; et al. (6 authors)

Differentiation Between Specific and Nonspecific Effects Related to P-Glycoprotein Inhibition in Immortalized Rat Brain Endothelial Cells

Bergmann, R.; Brust, P.; Johannsen, B.

  • International Journal of Clinical Pharmacology and Therapeutics, Vol. 36, No. 1, 1998 (46-49)

Stability versus Reactivity of "3+1" Mixed-Ligand Technetium-99m Complexes in Vitro and in Vivo

Syhre, R.; Seifert, S.; Spies, H.; Gupta, A.; Johannsen, B.

N.C.A.11C-Labelling of Benzenoid Compounds in Ring Positions: Synthesis of 3-Nitro-/ 3-11C/ Toluene and 4-Nitro-/ 4-11C/ Toluene and Their Corresponding Toluidines

Mäding, P.; Steinbach, J.

Nicotinamide-Substituted Complexes as Redox Marker

Knieß, T.; Spies, H.; Brandau, W.; Johannsen, B.

Simultaneous Measurement of 18F-FDOPA Metabolism and Cerebral Blood Flow in Newborn Piglets

Brust, P.; Bauer, R.; Walter, B.; Bergmann, R.; Füchtner, F.; et al. (9 authors)

11C-Labelling of Heterocyclic Aromatic Compounds in Ring Positions: Synthesis of 2-11C Indole

Zessin, J.; Steinbach, J.

  • Journal of Labelled Compounds and Radiopharmaceuticals XLI, 669-676 (1998)

Synthesis of Oxorhenium(V) Complexes Derived from 7-alpha-Functionalized Testosterone: First Rhenium-Containing Testosterone Derivatives

Wüst, F.; Scheller, D.; Spies, H.; Johannsen, B.

Novel Rhenium Complexes Derived from ALPHA-Tropanol as Potential Ligands for the Dopamin Transporter

Hoepping, A.; Brust, P.; Berger, R.; Leibnitz, P.; Spies, H.; et al. (8 authors)

1997

Technetium and rhenium complexes with thioether ligands. VI. Synthesis and structural characterization of mixed-ligand oxorhenium(V) complexes containing bidentate dithioethers and monothiolato ligands.

Reisgys, M.; Spies, H.; Johannsen, B.; Leibnitz, P.; Pietzsch, H.-J.

  • Chem. Ber. 130 (1997) 1343-1347

Uptake of 169Yb complexes in normal and tumour cells: influence of ligand and metabolic cell activity and stabilityx of cellular association

Kampf, G.; Knop, G.; Franke, W.-G.; Bergmann, R.; Johannsen, B.

  • Nucl. Med. Biol. 24 (1997) 349-355

Different response of cerebral and non-cerebral endothelial cells to cytotoxic hypoxia

Ahlemeyer, B.; Brust, P.; Johannsen, B.

  • Neurochem. Int. 31 (1997) 39-44

Technetium Coordination Ability of Cysteine-containing Peptides: X-ray Absorption Spectroscopy of a 99Tc Labeled Endothelin Derivate

Johannsen, B.; Jankowsky, R.; Noll, B.; Spies, H.; Reich, T.; et al. (9 authors)

  • Applied Radiation and Isotopes 48,1045 (1997)

N.C.A.11C-Labelling of Benzenoid Compounds in Ring Positions: [11C]Anisole Derivatives

Mäding, P.; Steinbach, J.; Johannsen, B.

  • Journal of Labelled Compounds and Radiopharmaceuticals 39 (7): 585-599 JUL 1997

Synthesis of Rhenium(I) and Technetium(I) Carbonyl/Dithioether Ligand Complexes Bearing 3,17-BETA-Estradiol

Reisgys, M.; Wüst, F.; Alberto, R.; Schibli, R.; Schubiger, P. A.; et al. (8 authors)

Synthesis and Structural Characterization of Neutral Oxorhenium(V) Complexes with Tridentate Dithioethers

Pietzsch, H.-J.; Reisgys, M.; Spies, H.; Leibnitz, P.; Johannsen, B.

  • Chemische Berichte 130 (1997) pp. 357-361

Technetium Coordination Ability of Cysteine-containing Peptides: X-ray Absorption Spectroscopy of a 99 Tc Labelled Endothelin Derivative

Johannsen, B.; Jankowsky, R.; Noll, B.; Spies, H.; Reich, T.; et al. (9 authors)

  • Applied Radiation and Isotopes Vol. 48, No. 8, pp. 1045-1050, 1997

Synthesis and Molecular Structure of a Rhenium Complex derived from 6-Methyl-8 Alpha-amino-ergoline

Spies, H.; Noll, B.; Noll, S.; Findeisen, A.; Leibnitz, P.; et al. (7 authors)

  • Chemische Berichte, Recueil 1997, 130, 839-841

Advances in technetium chemistry towards 99m Tc receptor imaging agents

Johannsen, B.; Spies, H.

  • Transition Metal Chemistry, 22. 318-320 (1997)

Synthesis of 17 Alpha-Substituted Mercaptoalkynyl Derivatives of 3,17 Beta-Estradiol

Wüst, F.; Spies, H.; Johannsen, B.

  • Tetrahedron Letters 38 (1997) 17 pp. 2931-2932

EXAFS Investigations on the Interaction of Uranium(VI) with Natural and Synthetic Humic Acids

Denecke, M. A.; Pompe, S.; Reich, T.; Moll, H.; Bubner, M.; et al. (8 authors)

  • Radiochimica Acta 79 (1997), 151-159

A Simple and Effecient Synthesis of a Derivatized Pseudotripeptide containing a Methylene Thioether Isoster and its Use for the Design of Bifunctional Rhenium and Technetium Chelating Agents

Scheunemann, M.; Johannsen, B.

  • Tetrahedron Letters 38 (1997) 1371-1372

Synthesis and Molecular Structure of a Rhenium Complex Derived from 8-alpha-Amino-6-methyl-ergoline

Spies, H.; Noll, B.; Noll, S.; Findeisen, M.; Leibnitz, P.; et al. (7 authors)

  • Chemische Berichte, Recueil 1997, 130, 839-841

Enzymatic Hydrolysis of Ester Groups of Mixed-Ligand Oxorhenium (V) and Oxotechnetium (V) Complexes

Seifert, S.; Syhre, R.; Spies, H.; Johannsen, B.

  • Applied Radiation and Isotopes Vol. 48, No. 8, pp. 1051-1057, 1997

Structural modification of receptor binding 99m-Tc complexes in order to improve brain uptake

Johannsen, B.; Berger, R.; Brust, P.; Pietzsch, H.-J.; Scheunemann, M.; et al. (8 authors)

  • European Journal of Nuclear Medicine 24 (1997) 3 pp. 316-319

Technetium and Rhenium Complexes with Thioether Ligands, 5 Synthesis and Structural Characterization of Neutral Oxorhenium (V) Complexes with Tridentate Dithioethers

Pietzsch, H.-J.; Reisgys, M.; Spies, H.; Leibnitz, P.; Johannsen, B.

  • Chemische Berichte, Recueil 1997, 130, 357-361

Preparation and Characterization of Novel Mixed-Ligand Complexes Bearing up to Four Ester Groups

Seifert, S.; Hoepping, A.; Klostermann, K.; Spies, H.; Johannsen, B.

  • Applied Radiation and Isotopes, 48 (1997) 943-948

Unexpected formation of the new oxorhenium (V) complex [ReO(NH(CH2CH2S)2)(SC6H5)] obtained by N-C cleavage of the tripodal ligand N(CH2CH2SH)3

Glaser, M.; Spies, H.; Berger, R.; Hahn, F. E.; Lügger, T.; et al. (6 authors)

  • Inorganica Chimica Acta 257 (1997) 143-147

Technetium and rhenium complexes of mercaptoacetyl glycine ligands 2. Formation and molecular structure of Re(V) complexes with mercaptoacetyl glycine and mercaptoacetyl glycine ethylester

Noll, B.; Noll, S.; Leibnitz, P.; Spies, H.; Schulze, P. E.; et al. (7 authors)

  • Inorganica Chimica Acta 255 (1997) 399-403

1996

A Comparison of Natural Humic Acids with Synthetic Humic Acid Model Substances: Characterization and Interaction with Uranium (VI)

Pompe, S.; Bubner, M.; Denecke, M. A.; Reich, T.; Brachmann, A.; et al. (9 authors)

  • Radiochimica Acta 74 (1996) pp. 135-140

Synthesis of "3+1"-mixed-ligand oxorhenium(V) complexes containing modified 3,17ß-Estradiol

Wüst, F.; Spies, H.; Johannsen, B.

  • Bioorganic and Medicinal Chemistry Letters 6 (1996) 22 pp.2729-2734

Retropane - a new Rhenium-Complex as a potential Ligand to label the Dopamin-Transporter

Hoepping, A.; Spies, H.; Johannsen, B.

  • Bioorganic and Medicinal Chemistry Letters 6 (1996) 23 pp. 2871-2874

Aufnahme und Verteilung von Trichloressigsäure in Trieben Norwegischer Fichte

Uhlirova, H.; Matucha, M.; Kretzschmar, M.; Bubner, M.

  • Umweltwissenschaften und Schadstoff-Forschung: Zeitschrift für Umweltchemie und Ökotoxikologie 8 (1996) 3 pp. 138-142

High-affinity binding of [3H]paroxetine to caudate nucleus and microvessels from porcine brain

Brust, P.; Bergmann, R.; Johannsen, B.

Mixed-Ligand Oxorhenium(V) comlexes with Rhenium-Selenium bonds. Molecular structure of (3-Oxapentane-1.5-Dithiolato)-(Benzeneselenolato)Oxorhenium(V)

Fietz, T.; Spies, H.; Leibnitz, P.; Scheller, D.

Studies to the Synthesis of 16 alpha-[18F] Fluoroestradiol

Römer, J.; Steinbach, J.; Kasch, H.

Technetium(V) and Rhenium(V) Complexes for 5-HT2A Serotonin Receptor Binding: Structure-Affinity Considerations

Johannsen, B.; Scheunemann, M.; Spies, H.; Brust, P.; Wober, J.; et al. (7 authors)

Rhenium(V) gluconate, a suitable precursor for the preparation of rhenium(V) complexes

Noll, B.; Knieß, T.; Friebe, M.; Spies, H.; Johannsen, B.

Basic Hydrolysis of 2-(18F)Fluoro-1,3,4,6-tetra-0-acetyl-D-glucose in the Preparation of 2-(18F)Fluoro-2-deoxy-D-glucose

Füchtner, F.; Steinbach, J.; Mäding, P.; Johannsen, B.

1995

Synthesis and reactions of trigonal-bipyramidal rhenium and technetium complexes with a tripodal, tetradentate NS3 ligand*

Spies, H.; Glaser, M.; Pietzsch, H.-J.; Hahn, F. E.; Lügger, T.

  • Inorganica Chimica Acta 240 (1995) pp. 465-478

Sources of radiochemical impurities in the 99mTc/S-unprotected MAG3 system

Noll, B.; Johannsen, B.; Spies, H.

Specific binding of (3H)imipramine indicates the presence of a specific serotonin transport system on endothelial cells of porcine brain

Brust, P.; Bergmann, R.; Johannsen, B.

Neutral Oxorhenium(V) Complexes with Tridentate Dithiolates and Monodentate Alkane- or Arene-thiolate Coligands

Spies, H.; Fietz, T.; Pietzsch, H.-J.; Johannsen, B.; Leibnitz, P.; et al. (8 authors)

  • Journal of the Chemical Society Dalton Transactions (1995) 13 pp. 2277-2280
    DOI: 10.1039/dt9950002277

Synthesis and characterization of isocyanide containing rhenium(III) complexes trans-[ReCl3(CNR)(PPh3)2] and crystal structure of trans-[ReCl3(CN-t-C4H9)(PPh3)2]

Spies, H.; Glaser, M.; Hahn, F. E.; Lügger, T.; Scheller, D.

Evaluation of Radioselenium Labeled Selenomethionine, a Potential Tracer for Brain Protein Synthesis by PET

Bergmann, R.; Brust, P.; Kampf, G.; Coenen, H. H.; Stöcklin, G.

Technetium- and Rhenium Complexes with Thioether Ligands-IV. Synthesis and Structural Characterization of Binuclear Oxorhenium (V) Complexes with Bidentate Thioether Coordination

Pietzsch, H.-J.; Spies, H.; Leibnitz, P.; Reck, G.

Functionalization of Technetium Complexes to Make Them Active in Vivo

Spies, H.; Johannsen, B.

Synthesis and molecular structure of chlore(3-thiapentane-1.5-dithiolato)oxorhenium(V)

Fietz, T.; Spies, H.; Pietzsch, H.-J.; Leibnitz, P.

High Specific Activity 17alpha-Cyanomethyl-17ß-hydroky-[14alpha, 15alpha-3H]estra-4,9-dien-3-one

Droescher, P.; Römer, J.

1994

Entwicklungen in der Technetiumchemie für die Nuklearmedizin

Johannsen, B.

  • Nuclear Medizin 33 (1994) A 90 (Abstract)

The fractal dimension of young colonies of macrophomina phaseolina produced from microsclerotia

Mihail, J. D.; Obert, M.; Taylor, S. J.; Bruhn, J. N.

  • Mycologia 86 (1994) pp. 350

Studies of radiometal uptake by cultured normal and tumor cells

Kampf, G.; Knop, G.; Wenzel, U.; Wunderlich, G.; Bergmann, R.; et al. (6 authors)

  • European Journal of Nuclear Medicine 21 (1994) pp. 874

Beziehungen zwischen der 169Yb-Aufnahme in Normal- und Tumorzellen und deren metabolischer Aktivität in Abhängigkeit von der Ligandspezies

Kampf, G.; Knop, G.; Matys, S.; Kunz, G.; Wenzel, U.; et al. (7 authors)

  • Nuklearmedizin 33 (1994) A 82

Characterization of serotonin uptake sites on the blood brain barrier

Brust, P.; Bergmann, R.

  • Journal of Neurochemistry 63 (1994) (Suppl. 1) S13C

Compartmental analysis of blood brain transfer and protein incorporation of L-[75Se]seleno methionine in rat brain

Bergmann, R.; Brust, P.; Coenen, H. H.; Stöcklin, G.

  • Journal of Neurochemistry 63 (1994) (Suppl. 1) S78C

N.C.A. 11C-labelling of aromatic compounds in the ring-position: synthesis of nitro-[1-11C]benzene and [1-11C]aniline

Steinbach, J.; Mäding, P.; Füchtner, F.; Johannsen, B.

Developmental changes of enzymes involved in peptide degradation in isolated rat brain microvessels

Brust, P.; Bech, A.; Kretzschmar, R.; Bergmann, R.

Trigonal-bipyramidale Technetium- und Rhenium-Komplexe mit vierzähnigen tripodalen NS3-Liganden

Spies, H.; Glaser, M.; Pietzsch, H.-J.; Hahn, F. E.; Kintzel, O.; et al. (6 authors)

  • Angewandte Chemie 106 (1994) 13 pp. 1416-1419

High Concentrated [99mTc] Pertechnetate Solutions from (n,y) 99Mo/99mTc Generators for Nuclear Medical Use

Seifert, S.; Wagner, G.; Eckardt, A.

  • Applied Radiation and Isotopes 45 (1994) 5, pp. 577-579

1993

Technetium Complexes with Thioether Ligands

Pietzsch, H.-J.; Spies, H.; Leibnitz, P.; Reck, G.; Johannsen, B.

Occurence and Nature of Different Tc(V) and Re(V) Complexes with Mercapto/Amide Ligands

Johannsen, B.; Noll, B.; Leibnitz, P.; Reck, G.; Noll, S.; et al. (6 authors)

Technetium and rhenium complexes of mercapto-containing peptides - 1. Tc(V) and Re(V) complexes with mercaptoacetyl diglycine (MAG2) and X-ray structure of AsPh4[TcO(MAG2)] x C2H5OH

Johannsen, B.; Noll, B.; Noll, S.; Spies, H.; Leibnitz, P.; et al. (6 authors)

Technetium Complexes with Thioether Ligands - III. Synthesis and Structural Characterization of Cationic Nitridotechnetium(V) Complexes with Thiacrown ethers

Pietzsch, H.-J.; Spies, H.; Leibnitz, P.; Reck, G.

  • Polyhedron 12 (1993) 24 pp. 2995-3002

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